PepDiana
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Primary experimental recordPositive observation

PMC12677653::ACT031868

Insig1/2 loop 1 peptide

Evidence text

Paper-level observation

combination of semaglutide and the Insig1/2 loop 1 peptide demonstrated additive antitumor effects in mice fed a high-fat diet (Figure 5a-c)
textConfidence: medium

Assay observation

Activity
Anticancer
Subtype
Antibacterial
Measure
percent_inhibition
Comparator
=
Raw observation
additive antitumor effects
Normalized measurement
=2
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Mus musculus
Assay method
Not reported by source
Sequence
LYPCIDSHLGEPHKFKRE
Standardization
ready simple

Source publication

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science · 2025

DOI 10.1002/advs.202508111 PMC12677653
Parent mention

Related peptide identities

PEPDIA-PLP-001956

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.