PepDiana
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Primary experimental recordPositive observation

PMC12677653::ACT031863

Insig1/2 loop 1 peptide

Evidence text

Paper-level observation

peptide treatment ... induced cell death in HCT116 human colon cancer cells (Figure S1i)
textConfidence: medium

Assay observation

Activity
Anticancer
Subtype
Cytotoxic
Measure
cell_viability
Comparator
=
Raw observation
induced cell death
Normalized measurement
=16
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Homo sapiens
Assay method
Not reported by source
Sequence
LYPCIDSHLGEPHKFKRE
Standardization
ready simple

Source publication

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science · 2025

DOI 10.1002/advs.202508111 PMC12677653
Parent mention

Related peptide identities

PEPDIA-PLP-001956

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.