PepDiana
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Primary experimental recordPositive observation

PMC12474311::ACT027060

NY-ESO-1 157-165 epitope

Evidence text

Paper-level observation

Endogenous NY-ESO-1 peptide presented by HLA-A*02:01, HLA-A*02:03, HLA-A*02:05, HLA-A*02:06, and HLA-A*02:10 significantly induced TCR-T cells to secrete higher levels of IFN-γ than control T cells (Section 3.2, Figure 2b).
textConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
T-cell activation
Measure
qualitative
Comparator
=
Raw observation
active
Normalized measurement
=1
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
COS-7-NY-A*02:01
Assay method
Not reported by source
Sequence
SLLMWITQC
Standardization
ready simple

Source publication

TCR-T Cell Recognition of an NY-ESO-1 Epitope Presented by HLA-A2 Supertype: Implications for Cancer Immunotherapy

Vaccines · 2025

DOI 10.3390/vaccines13090898 PMC12474311
Parent mention

Related peptide identities

PEPDIA-PLP-002699

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.