PepDiana
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Primary experimental recordPositive observation

PMC10668963::ACT002843

A45-LNA

Evidence text

Paper-level observation

Table 1: A45-LNA EC50/IC50 0.3 ± 0.1 µM (EMSA).
tableConfidence: medium

Assay observation

Activity
Antiviral
Subtype
General Antiviral
Measure
EC50
Comparator
=
Raw observation
0.3 ± 0.1 µM (EMSA)
Normalized measurement
=0.3 µM
Value minimum
0.2 µM
Value maximum
0.4 µM
Target
SARS-CoV-2
Assay method
Not reported by source
Sequence
Not reported by source
Standardization
insufficient information

Source publication

Unwinding the SARS-CoV-2 Ribosomal Frameshifting Pseudoknot with LNA and G-Clamp-Modified Phosphorothioate Oligonucleotides Inhibits Viral Replication

Biomolecules · 2023

DOI 10.3390/biom13111660 PMC10668963
Parent mention

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.