Hydralazine
(ZUXNZUWOTSUBMN-UHFFFAOYSA-N)
Structure
- SMILES
- NNc1nncc2c1cccc2.Cl
- Molecular Formula:
- C8H9ClN4
- Molecular Weight:
- 196.637
- Log P:
- 2.4907
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 3
- TPSA:
- 63.83
- CAS Number(s):
- 304-20-1; 81411-23-6; 1044569-46-1
Synonym(s)
1.
Hydralazine
2.
Hydrallazin
3.
Apresoline
4.
Apressin
5.
Apressoline
6.
Hydralazine Hydrochloride
7.
Hydralazine mono-Hydrochloride
8.
Hydrazinophthalazine
9.
Nepresol
10.
Hydralazine mono Hydrochloride
11.
Hydrochloride, Hydralazine
12.
mono-Hydrochloride, Hydralazine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Anti-neutrophil cytoplasmic antibody positive vasculitis | FAERS: 80 | US FAERS | |
| 2 | Vasculitis | FAERS: 30 | US FAERS | |
| 3 | Lupus-like syndrome | FAERS: 27 | US FAERS | |
| 4 | Glomerulonephritis | FAERS: 26 | US FAERS | |
| 5 | Hypotension | FAERS: 19 | US FAERS | |
| 6 | Acute kidney injury | FAERS: 15 | US FAERS | |
| 7 | Drug ineffective | FAERS: 15 | US FAERS | |
| 8 | Dizziness | FAERS: 14 | US FAERS | |
| 9 | Nausea | FAERS: 14 | US FAERS | |
| 10 | Headache | FAERS: 12 | US FAERS | |
| 11 | Maternal exposure during pregnancy | FAERS: 12 | US FAERS | |
| 12 | Proteinuria | FAERS: 12 | US FAERS | |
| 13 | Chest Pain | FAERS: 11 | US FAERS | |
| 14 | Arthralgia | FAERS: 9 | US FAERS | |
| 15 | Low birth weight baby | FAERS: 9 | US FAERS | |
| 16 | Lupus Nephritis | FAERS: 9 | US FAERS | |
| 17 | Toxicity to various agents | FAERS: 9 | US FAERS | |
| 18 | Flushing | FAERS: 8 | US FAERS | |
| 19 | Asthenia | FAERS: 7 | US FAERS | |
| 20 | Blood pressure inadequately controlled | FAERS: 7 | US FAERS | |
| 21 | Fatigue | FAERS: 7 | US FAERS | |
| 22 | Palpitations | FAERS: 7 | US FAERS | |
| 23 | Pulmonary renal syndrome | FAERS: 7 | US FAERS | |
| 24 | Renal vasculitis | FAERS: 7 | US FAERS | |
| 25 | Vomiting | FAERS: 7 | US FAERS | |
| 26 | Anxiety | FAERS: 6 | US FAERS | |
| 27 | Autoimmune hepatitis | FAERS: 6 | US FAERS | |
| 28 | Drug dispensing error | FAERS: 6 | US FAERS | |
| 29 | Drug exposure during pregnancy | FAERS: 6 | US FAERS | |
| 30 | Medication Error | FAERS: 6 | US FAERS | |
| 31 | Myalgia | FAERS: 6 | US FAERS | |
| 32 | Nephritis | FAERS: 6 | US FAERS | |
| 33 | Angioedema | FAERS: 5 | US FAERS | |
| 34 | Cardiac Arrest | FAERS: 5 | US FAERS | |
| 35 | Hepatic necrosis | FAERS: 5 | US FAERS | |
| 36 | Hypersensitivity | FAERS: 5 | US FAERS | |
| 37 | Malaise | FAERS: 5 | US FAERS | |
| 38 | Respiratory distress | FAERS: 5 | US FAERS | |
| 39 | Tremor | FAERS: 5 | US FAERS | |
| 40 | Blood creatinine increased | FAERS: 4 | US FAERS | |
| 41 | Chills | FAERS: 4 | US FAERS | |
| 42 | Epiglottis ulcer | FAERS: 4 | US FAERS | |
| 43 | Gangrene | FAERS: 4 | US FAERS | |
| 44 | Pericardial effusion | FAERS: 4 | US FAERS | |
| 45 | Product quality issue | FAERS: 4 | US FAERS | |
| 46 | Supraventricular tachycardia | FAERS: 4 | US FAERS | |
| 47 | Angina Pectoris | FAERS: 3 | US FAERS | |
| 48 | Arthritis | FAERS: 3 | US FAERS | |
| 49 | Chest discomfort | FAERS: 3 | US FAERS | |
| 50 | Erythema | FAERS: 3 | US FAERS | |
| 51 | Histone antibody positive | FAERS: 3 | US FAERS | |
| 52 | Hypocomplementaemia | FAERS: 3 | US FAERS | |
| 53 | Live Birth | FAERS: 3 | US FAERS | |
| 54 | Pericarditis | FAERS: 3 | US FAERS | |
| 55 | Product label issue | FAERS: 3 | US FAERS | |
| 56 | Respiratory Failure | FAERS: 3 | US FAERS | |
| 57 | Tachycardia | FAERS: 3 | US FAERS | |
| 58 | Antiphospholipid antibodies positive | FAERS: 2 | US FAERS | |
| 59 | Atrial Fibrillation | FAERS: 2 | US FAERS | |
| 60 | C3 glomerulopathy | FAERS: 2 | US FAERS | |
| 61 | Cardiac Tamponade | FAERS: 2 | US FAERS | |
| 62 | Cheilitis | FAERS: 2 | US FAERS | |
| 63 | Circumstance or information capable of leading to medication error | FAERS: 2 | US FAERS | |
| 64 | Dehydration | FAERS: 2 | US FAERS | |
| 65 | Dysphonia | FAERS: 2 | US FAERS | |
| 66 | Eclampsia | FAERS: 2 | US FAERS | |
| 67 | Eyelid rash | FAERS: 2 | US FAERS | |
| 68 | Feeling Cold | FAERS: 2 | US FAERS | |
| 69 | Feeling abnormal | FAERS: 2 | US FAERS | |
| 70 | Hypertensive emergency | FAERS: 2 | US FAERS | |
| 71 | Hypoxia | FAERS: 2 | US FAERS | |
| 72 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 73 | Joint swelling | FAERS: 2 | US FAERS | |
| 74 | Leukocytoclastic vasculitis | FAERS: 2 | US FAERS | |
| 75 | Lupus pneumonitis | FAERS: 2 | US FAERS | |
| 76 | Mucocutaneous rash | FAERS: 2 | US FAERS | |
| 77 | Pain | FAERS: 2 | US FAERS | |
| 78 | Pancytopenia | FAERS: 2 | US FAERS | |
| 79 | Physical product label issue | FAERS: 2 | US FAERS | |
| 80 | Pleuritic pain | FAERS: 2 | US FAERS | |
| 81 | Pneumonia | FAERS: 2 | US FAERS | |
| 82 | Product dispensing error | FAERS: 2 | US FAERS | |
| 83 | Purpura | FAERS: 2 | US FAERS | |
| 84 | Retinal Vasculitis | FAERS: 2 | US FAERS | |
| 85 | Septic Shock | FAERS: 2 | US FAERS | |
| 86 | Swelling | FAERS: 2 | US FAERS | |
| 87 | Tinnitus | FAERS: 2 | US FAERS | |
| 88 | Tongue eruption | FAERS: 2 | US FAERS | |
| 89 | Urticaria | FAERS: 2 | US FAERS | |
| 90 | Wrong drug administered | FAERS: 2 | US FAERS | |
| 91 | jaundice | FAERS: 2 | US FAERS | |
| 92 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 93 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 94 | Accidental overdose | FAERS: 1 | US FAERS | |
| 95 | Acquired porphyria | FAERS: 1 | US FAERS | |
| 96 | Activities of daily living impaired | FAERS: 1 | US FAERS | |
| 97 | Agitation | FAERS: 1 | US FAERS | |
| 98 | Agranulocytosis | FAERS: 1 | US FAERS | |
| 99 | Alanine Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 100 | Alopecia | FAERS: 1 | US FAERS | |
| 101 | Anaphylactoid syndrome of pregnancy | FAERS: 1 | US FAERS | |
| 102 | Anger | FAERS: 1 | US FAERS | |
| 103 | Antinuclear antibody increased | FAERS: 1 | US FAERS | |
| 104 | Aphasia | FAERS: 1 | US FAERS | |
| 105 | Arterial thrombosis | FAERS: 1 | US FAERS | |
| 106 | Ascites | FAERS: 1 | US FAERS | |
| 107 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 108 | Atrial Flutter | FAERS: 1 | US FAERS | |
| 109 | Autoimmune nephritis | FAERS: 1 | US FAERS | |
| 110 | Back Pain | FAERS: 1 | US FAERS | |
| 111 | Bicuspid aortic valve | FAERS: 1 | US FAERS | |
| 112 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 113 | Blood urea increased | FAERS: 1 | US FAERS | |
| 114 | Blood urine present | FAERS: 1 | US FAERS | |
| 115 | Cardiac enzymes increased | FAERS: 1 | US FAERS | |
| 116 | Cardiac infection | FAERS: 1 | US FAERS | |
| 117 | Carotid artery occlusion | FAERS: 1 | US FAERS | |
| 118 | Cerebrovascular accident | FAERS: 1 | US FAERS | |
| 119 | Cholecystitis | FAERS: 1 | US FAERS | |
| 120 | Cholelithiasis | FAERS: 1 | US FAERS | |
| 121 | Cholestasis | FAERS: 1 | US FAERS | |
| 122 | Chromaturia | FAERS: 1 | US FAERS | |
| 123 | Complement factor C3 decreased | FAERS: 1 | US FAERS | |
| 124 | Complement factor C4 decreased | FAERS: 1 | US FAERS | |
| 125 | Congenital anomaly in offspring | FAERS: 1 | US FAERS | |
| 126 | Constipation | FAERS: 1 | US FAERS | |
| 127 | Contraindicated drug administered | FAERS: 1 | US FAERS | |
| 128 | Cyanosis | FAERS: 1 | US FAERS | |
| 129 | Depressed Level of Consciousness | FAERS: 1 | US FAERS | |
| 130 | Diffuse alveolar damage | FAERS: 1 | US FAERS | |
| 131 | Disseminated Intravascular Coagulation | FAERS: 1 | US FAERS | |
| 132 | Diverticular perforation | FAERS: 1 | US FAERS | |
| 133 | Double stranded DNA antibody positive | FAERS: 1 | US FAERS | |
| 134 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 135 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 136 | Dry gangrene | FAERS: 1 | US FAERS | |
| 137 | Electrocardiogram U-wave abnormality | FAERS: 1 | US FAERS | |
| 138 | Emotional disorder | FAERS: 1 | US FAERS | |
| 139 | Epistaxis | FAERS: 1 | US FAERS | |
| 140 | Gastrointestinal melanosis | FAERS: 1 | US FAERS | |
| 141 | Gout | FAERS: 1 | US FAERS | |
| 142 | Granulomatosis with polyangiitis | FAERS: 1 | US FAERS | |
| 143 | HELLP Syndrome | FAERS: 1 | US FAERS | |
| 144 | Hepatic infection bacterial | FAERS: 1 | US FAERS | |
| 145 | Hepatitis | FAERS: 1 | US FAERS | |
| 146 | Hypophagia | FAERS: 1 | US FAERS | |
| 147 | IgM nephropathy | FAERS: 1 | US FAERS | |
| 148 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 149 | Impaired work ability | FAERS: 1 | US FAERS | |
| 150 | Infection | FAERS: 1 | US FAERS | |
| 151 | Inflammation | FAERS: 1 | US FAERS | |
| 152 | Leukopenia | FAERS: 1 | US FAERS | |
| 153 | Livedo Reticularis | FAERS: 1 | US FAERS | |
| 154 | Mental status changes | FAERS: 1 | US FAERS | |
| 155 | Mesangioproliferative glomerulonephritis | FAERS: 1 | US FAERS | |
| 156 | Mood swings | FAERS: 1 | US FAERS | |
| 157 | Multiple Myeloma | FAERS: 1 | US FAERS | |
| 158 | Myocarditis | FAERS: 1 | US FAERS | |
| 159 | Nephrosclerosis | FAERS: 1 | US FAERS | |
| 160 | Nephrotic Syndrome | FAERS: 1 | US FAERS | |
| 161 | Night sweats | FAERS: 1 | US FAERS | |
| 162 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 163 | Pallor | FAERS: 1 | US FAERS | |
| 164 | Paranoia | FAERS: 1 | US FAERS | |
| 165 | Peripartum cardiomyopathy | FAERS: 1 | US FAERS | |
| 166 | Petechiae | FAERS: 1 | US FAERS | |
| 167 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 168 | Productive Cough | FAERS: 1 | US FAERS | |
| 169 | Pruritus | FAERS: 1 | US FAERS | |
| 170 | Quality of life decreased | FAERS: 1 | US FAERS | |
| 171 | Rales | FAERS: 1 | US FAERS | |
| 172 | Rash erythematous | FAERS: 1 | US FAERS | |
| 173 | Rheumatoid Arthritis | FAERS: 1 | US FAERS | |
| 174 | Sepsis | FAERS: 1 | US FAERS | |
| 175 | Serositis | FAERS: 1 | US FAERS | |
| 176 | Skin Ulcer | FAERS: 1 | US FAERS | |
| 177 | Skin lesion | FAERS: 1 | US FAERS | |
| 178 | Syncope | FAERS: 1 | US FAERS | |
| 179 | Tension Headache | FAERS: 1 | US FAERS | |
| 180 | Tension | FAERS: 1 | US FAERS | |
| 181 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 182 | Transaminases increased | FAERS: 1 | US FAERS | |
| 183 | Troponin increased | FAERS: 1 | US FAERS | |
| 184 | Vanishing bile duct syndrome | FAERS: 1 | US FAERS | |
| 185 | Venous Thrombosis | FAERS: 1 | US FAERS | |
| 186 | Vertigo | FAERS: 1 | US FAERS | |
| 187 | Weight decreased | FAERS: 1 | US FAERS | |
| 188 | Wheezing | FAERS: 1 | US FAERS | |
| 189 | nervous system disorder | FAERS: 1 | US FAERS |
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