tetrandrine
(WVTKBKWTSCPRNU-KYJUHHDHSA-N)
Structure
- SMILES
- COc1c(OC)cc2c3c1Oc1cc4c(cc1OC)CCN([C@H]4Cc1ccc(Oc4cc(C[C@@H]3N(CC2)C)ccc4OC)cc1)C
- Type(s)
- Experimental
- Molecular Formula:
- C38H42N2O6
- Molecular Weight:
- 622.750
- Log P:
- 7.0382
- Hydrogen Bond Acceptor:
- 8
- Hydrogen Bond Donor:
- 0
- TPSA:
- 61.86
- CAS Number(s):
- 477-57-6; 518-34-3; 23495-89-8
Synonym(s)
1.
tetrandrine
2.
6,6',7,12-tetramethoxy-2,2'-dimethyl-1 beta-berbaman
3.
NSC-77037
4.
d-tetrandrine
5.
hanjisong
6.
isotetrandrine
7.
isotetrandrine dihydrochloride
8.
tetradrine
9.
tetrandrine dihydrochloride, (1beta)-isomer
10.
tetrandrine, (1'beta)-isomer
External Link(s)
| MeSH | C009438 |
| PubChem Compound | 73078 |
| ChEBI | 49 |
| CHEMBL | CHEMBL176045 |
| DrugBank | DB14066 |
| KEGG | cpd:C09654 |
| Therapeutic Target Database | D0AN2Q D0G4ES |
| ZINC | 28116057 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Arthritis | 26640276 | CTD | |
| 2 | Bone Marrow Diseases | 16219352 | CTD | |
| 3 | Heart Diseases | 3712522 20845809 | CTD | |
| 4 | Hemorrhage | 21992520 | CTD | |
| 5 | Hypoxia | 3712522 | CTD | |
| 6 | Infection | 16219352 | CTD | |
| 7 | Ischemia | 20554997 | CTD | |
| 8 | Liver Cirrhosis, Experimental | 17201889 | CTD | |
| 9 | Lung Injury | 21992520 | CTD | |
| 10 | Mitochondrial Diseases | 20845809 | CTD | |
| 11 | Myocardial Infarction | 20554997 | CTD | |
| 12 | Necrosis | 3712522 20554997 | CTD | |
| 13 | Pleural Effusion, Malignant | 18495333 | CTD | |
| 14 | Stomatitis | 16219352 | CTD | |
| 15 | Thrombosis | 10193204 | CTD |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120262
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.