MetaADEDB 2.0 @ LMMD
Tolmetin
(UPSPUYADGBWSHF-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C
Type(s)
Approved
ATC code(s)
M01AB03; M02AA21
Molecular Formula:
C15H15NO3
Molecular Weight:
257.285
Log P:
2.1916
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
59.3
CAS Number(s):
26171-23-3
Synonym(s)
1.
Tolmetin
2.
McN-2559
3.
Tolectin
4.
Tolmetin Sodium
5.
Tolmetin Sodium Anhydrous
6.
Tolmetin Sodium, Anhydrous
7.
Tolmetin Sodium, Dihydrate
8.
Anhydrous Tolmetin Sodium
9.
Anhydrous, Tolmetin Sodium
10.
Dihydrate Tolmetin Sodium
11.
McN 2559
12.
McN2559
13.
Sodium Anhydrous, Tolmetin
14.
Sodium, Tolmetin
External Link(s)
MeSHD014046
PubChem Compound5509
BindingDB50295287
ChEBI71941
CHEMBLCHEMBL1020
DrugBankDB00500
DrugCentral2699
IUPHAR/BPS Guide to PHARMACOLOGY7311
KEGGcpd:C07149
dr:D02355
Therapeutic Target DatabaseD09BHB
ZINC2191
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1UrticariaFAERS: 2
Canada Vigilance: 2		81404
4006743
11792017		CTD
SIDER
Canada Vigilance
US FAERS
2Capillary FragilityFAERS: 1US FAERS
3Gastric ulcerFAERS: 1US FAERS
4PoisoningFAERS: 1US FAERS
5Therapeutic response unexpectedFAERS: 1US FAERS
6Abdominal PainCanada Vigilance: 1Canada Vigilance
SIDER
7Abdominal discomfortSIDER
8Acute kidney injury2773031
3738663
6375363		CTD
9AgranulocytosisSIDER
10Anaphylactic shockSIDER
11Anaphylactoid ReactionSIDER
12Anemia, Hemolytic17381629CTD
13AngioedemaCanada Vigilance: 14006743CTD
Canada Vigilance
14AnxietyCanada Vigilance: 1Canada Vigilance
15Arthritis3684403
6473688		CTD
16AstheniaCanada Vigilance: 1Canada Vigilance
SIDER
17Bipolar Disorder6473688CTD
18Blood urea increasedSIDER
19Chemical and Drug Induced Liver Injury24085192CTD
20Chest PainSIDER
21Chest discomfortCanada Vigilance: 1Canada Vigilance
22ChillsCanada Vigilance: 2Canada Vigilance
23ConstipationSIDER
24Distress gastrointestinalSIDER
25DizzinessCanada Vigilance: 1Canada Vigilance
SIDER
26DrowsinessSIDER
27Drug Eruptions11792017CTD
28Duodenal UlcerCanada Vigilance: 1Canada Vigilance
29DyspepsiaSIDER
30DysuriaSIDER
31EpistaxisSIDER
32Erythema MultiformeSIDER
33Exfoliative rashCanada Vigilance: 1Canada Vigilance
34FatigueCanada Vigilance: 1Canada Vigilance
35Fatty Liver1863194CTD
36Fetal Growth Retardation15505808CTD
37FlatulenceSIDER
38GastritisSIDER
39Gastrointestinal PainSIDER
40GlossitisSIDER
41HeadacheSIDER
42Heart Septal Defects15505808CTD
43HepatitisSIDER
44HypotensionCanada Vigilance: 1Canada Vigilance
45Inflammation3291741CTD
46Juvenile pauciarticular chronic arthritis6829384CTD
47LymphadenopathySIDER
48MalaiseCanada Vigilance: 1Canada Vigilance
49Memory Disorders17266991CTD
50Multiple Organ Failure1863194CTD
51NauseaSIDER
52Nephritis, Interstitial3738663
3975749
6375363		CTD
53Nephrotic Syndrome2773972
6738768
7277633		CTD
54Pain3291741
3931315		CTD
55Protein urine presentSIDER
56Proteinuria6375363
8343194		CTD
SIDER
57PruritusCanada Vigilance: 6Canada Vigilance
58PurpuraSIDER
59Rash erythematousCanada Vigilance: 1Canada Vigilance
60Serum SicknessSIDER
61Skin irritationSIDER
62SomnolenceSIDER
63Stevens-Johnson Syndrome25811541CTD
64StomatitisCanada Vigilance: 1Canada Vigilance
SIDER
65SwellingCanada Vigilance: 1Canada Vigilance
66SyncopeCanada Vigilance: 2Canada Vigilance
67ThrombocytopeniaCanada Vigilance: 1Canada Vigilance
SIDER
68TinnitusSIDER
69Toxic Epidermal NecrolysisSIDER
70Urinary IncontinenceCanada Vigilance: 1Canada Vigilance
71Urinary tract infectionSIDER
72Vascular purpuraSIDER
73Visual ImpairmentSIDER
74Visual disturbanceSIDER
75VomitingSIDER
76Weight decreasedSIDER
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