MetaADEDB 2.0 @ LMMD
Micafungin
(KOOAFHGJVIVFMZ-WZPXRXMFSA-M)
Structure
SMILES
CCCCCOc1ccc(cc1)c1onc(c1)c1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@H](CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC1=O)[C@H](O)C)C[C@@H](C2)O)[C@@H]([C@H](c1ccc(c(c1)OS(=O)(=O)[O-])O)O)O)[C@@H](CC(=O)N)O)C.[Na+]
Molecular Formula:
C56H70N9NaO23S
Molecular Weight:
1292.260
Log P:
-0.8816
Hydrogen Bond Acceptor:
32
Hydrogen Bond Donor:
15
TPSA:
521.35
CAS Number(s):
208538-73-2
Synonym(s)
1.
Micafungin
2.
FK 463
3.
FK-463
4.
FK463
5.
Micafungin Sodium
6.
Mycamine
External Link(s)
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 9US FAERS
2AgranulocytosisFAERS: 3US FAERS
3Bronchopulmonary AspergillosisFAERS: 3US FAERS
4Alanine Aminotransferase IncreasedFAERS: 2SIDER
US FAERS
5Candida endophthalmitisFAERS: 2US FAERS
6Peritoneal effluent abnormalFAERS: 2US FAERS
7PneumoniaFAERS: 2SIDER
US FAERS
8RhabdomyolysisFAERS: 2US FAERS
9SepsisFAERS: 2SIDER
US FAERS
10Toxic Epidermal NecrolysisFAERS: 2SIDER
US FAERS
11AcidosisFAERS: 1SIDER
US FAERS
12Altered state of consciousnessFAERS: 1US FAERS
13Aspartate Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
14Blood creatine phosphokinase increasedFAERS: 1US FAERS
15Blood creatinine increasedFAERS: 1SIDER
US FAERS
16Blood potassium decreasedFAERS: 1US FAERS
17Blood urea increasedFAERS: 1SIDER
US FAERS
18Candida sepsisFAERS: 1US FAERS
19CellulitisFAERS: 1US FAERS
20DeafnessFAERS: 1US FAERS
21Disseminated Intravascular CoagulationFAERS: 1SIDER
US FAERS
22Drug ineffective for unapproved indicationFAERS: 1US FAERS
23Febrile NeutropeniaFAERS: 1SIDER
US FAERS
24HeadacheFAERS: 1SIDER
US FAERS
25InfectionFAERS: 1SIDER
US FAERS
26Infusion Site ExtravasationFAERS: 1US FAERS
27Intentional drug misuseFAERS: 1US FAERS
28Liver AbscessFAERS: 1US FAERS
29Maternal exposure during pregnancyFAERS: 1US FAERS
30Oral fungal infectionFAERS: 1US FAERS
31PalpitationsFAERS: 1SIDER
US FAERS
32Peritoneal fluid analysis abnormalFAERS: 1US FAERS
33Pulmonary necrosisFAERS: 1US FAERS
34Rectal tenesmusFAERS: 1US FAERS
35Renal abscessFAERS: 1US FAERS
36Respiratory FailureFAERS: 1US FAERS
37StillbirthFAERS: 1US FAERS
38Systemic mycosisFAERS: 1US FAERS
39TinnitusFAERS: 1US FAERS
40Urinary tract infection fungalFAERS: 1US FAERS
41VomitingFAERS: 1SIDER
US FAERS
42X-ray abnormalFAERS: 1US FAERS
43Abdominal PainSIDER
44Acquired Immunodeficiency SyndromeSIDER
45Acute Coronary SyndromeSIDER
46Anaemia NOS aggravatedSIDER
47Anaphylactic shockSIDER
48Anaphylactoid ReactionSIDER
49AnorexiaSIDER
50AnuriaSIDER
51AnxietySIDER
52ArthralgiaSIDER
53AspergillosisSIDER
54AstheniaSIDER
55Atrial FibrillationSIDER
56Back PainSIDER
57Blood alkaline phosphatase increasedSIDER
58Blood and lymphatic system disordersSIDER
59Blood lactate dehydrogenase increasedSIDER
60BradycardiaSIDER
61Cardiac ArrestSIDER
62ChillsSIDER
63CholestasisSIDER
64ConstipationSIDER
65CyanosisSIDER
66Deep Vein ThrombosisSIDER
67DeliriumSIDER
68DermatitisSIDER
69DizzinessSIDER
70Drug level increasedSIDER
71Drug resistanceCanada Vigilance: 1Canada Vigilance
72DysgeusiaSIDER
73DyspepsiaSIDER
74EosinophiliaSIDER
75EpistaxisSIDER
76Erythema MultiformeSIDER
77ErythemaSIDER
78FatigueSIDER
79Feeling abnormalSIDER
80Fluid overloadSIDER
81FlushingSIDER
82Gamma-Glutamyltransferase IncreasedSIDER
83Gastrointestinal PainSIDER
84HepatitisSIDER
85HepatomegalySIDER
86HypersensitivitySIDER
87HypotensionSIDER
88InfestationSIDER
89InflammationSIDER
90Infusion site inflammationSIDER
91Injection Site ReactionSIDER
92Injection site painSIDER
93Injection site thrombosisSIDER
94LeukopeniaSIDER
95LymphopeniaSIDER
96MalnutritionSIDER
97Musculoskeletal discomfortSIDER
98Myocardial InfarctionSIDER
99NauseaSIDER
100NeutropeniaSIDER
101OliguriaSIDER
102PancytopeniaSIDER
103Pericardial effusionSIDER
104PhlebitisSIDER
105PruritusSIDER
106Pulmonary EmbolismSIDER
107Renal failure aggravatedSIDER
108Renal tubular necrosisSIDER
109Septic ShockSIDER
110ShockSIDER
111Skin necrosisSIDER
112SomnolenceSIDER
113Stevens-Johnson SyndromeSIDER
114TachycardiaSIDER
115ThrombocytopeniaSIDER
116ThrombophlebitisSIDER
117Transaminases increasedSIDER
118TremorSIDER
119UrticariaSIDER
120White blood cell count decreasedSIDER
121jaundiceSIDER
122nervous system disorderSIDER
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