MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

cefditoren

(KMIPKYQIOVAHOP-YLGJWRNMSA-N)

Structure

SMILES: CO/N=C(\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)/C=C\c1scnc1C)/c1csc(n1)N
Type(s): Approved; Investigational
ATC code(s): J01DD16
Molecular Formula:: C19H18N6O5S3
Molecular Weight:: 506.578
Log P:: 2.2027
Hydrogen Bond Acceptor:: 14
Hydrogen Bond Donor:: 3
TPSA:: 241.88
CAS Number(s):: 104145-95-1

Synonym(s)

cefditoren

ME 1206

ME-1206

cefditoren, sodium salt, (6R-(3(Z),6alpha,7beta(Z)))-isomer

External Link(s)

MeSH	C073460
PubChem Compound	9870843
ChEBI	59343
CHEMBL	CHEMBL1743
DrugBank	DB01066
KEGG	cpd:C21546 dr:D01628 dr:D07639

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Arthritis	FAERS: 1		OFFSIDES US FAERS
2	Pallor	FAERS: 1		US FAERS
3	Pruritus	FAERS: 1		SIDER US FAERS
4	Rash erythematous	FAERS: 1		US FAERS
5	Abdominal Pain			OFFSIDES SIDER
6	Abdominal tenderness			OFFSIDES
7	Acid reflux			OFFSIDES
8	Agitation			SIDER
9	Agranulocytosis			SIDER
10	Alanine Aminotransferase Increased			SIDER
11	Anaphylactic shock			SIDER
12	Anaphylactoid Reaction			SIDER
13	Anhedonia			OFFSIDES
14	Anorexia			SIDER
15	Anxiety			OFFSIDES
16	Arthralgia			SIDER
17	Aspartate Aminotransferase Increased			SIDER
18	Asthenia			SIDER
19	Asthma			SIDER
20	Bacteria stool identified			OFFSIDES
21	Blood albumin decreased			SIDER
22	Blood alkaline phosphatase increased			SIDER
23	Blood creatinine increased			SIDER
24	Blood glucose increased			SIDER
25	Blood lactate dehydrogenase increased			SIDER
26	Blood potassium increased			SIDER
27	Blood urea increased			SIDER
28	Calcium low			SIDER
29	Catheter related infection			OFFSIDES
30	Cellulitis			OFFSIDES
31	Cholestasis			SIDER
32	Chronic sinusitis			OFFSIDES
33	Clostridium colitis			OFFSIDES
34	Cold sweat			OFFSIDES
35	Colitis			OFFSIDES SIDER
36	Constipation			SIDER
37	Creatinine increased			SIDER
38	Culture wound positive			OFFSIDES
39	Cyanosis			OFFSIDES
40	Demyelination			OFFSIDES
41	Dermatitis			SIDER
42	Diarrhea			OFFSIDES
43	Disability			SIDER
44	Disease recurrence			OFFSIDES
45	Diverticulum			OFFSIDES
46	Dizziness			SIDER
47	Drug ineffective			OFFSIDES
48	Dysgeusia			SIDER
49	Dyspepsia			OFFSIDES SIDER
50	Endodontic procedure			OFFSIDES
51	Eosinophilia			SIDER
52	Eosinophilic Pneumonia			SIDER
53	Epidural Abscess			OFFSIDES
54	Eructation			SIDER
55	Erythema Multiforme			SIDER
56	Eustachian tube disorder			OFFSIDES
57	Eyelid Diseases			OFFSIDES
58	Fatigue			OFFSIDES
59	Fibromyalgia			OFFSIDES
60	Flatulence			SIDER
61	Gastritis			SIDER
62	Gastrointestinal Pain			SIDER
63	General physical health deterioration			OFFSIDES
64	Glucose increased			SIDER
65	Headache			SIDER
66	Hyperkinesia			SIDER
67	Hypersensitivity			SIDER
68	Hypotension			SIDER
69	Initial insomnia			OFFSIDES
70	Intervertebral Disc Degeneration			OFFSIDES
71	Intraocular pressure test			OFFSIDES
72	Lactic dehydrogenase activity increased			SIDER
73	Leukopenia			SIDER
74	Leukorrhea			SIDER
75	Lymphocyte count increased			SIDER
76	Muscle strain			OFFSIDES
77	Musculoskeletal discomfort			SIDER
78	Myalgia			SIDER
79	Nasal discomfort			OFFSIDES
80	Nausea			OFFSIDES SIDER
81	Nervousness			SIDER
82	Neutropenia			SIDER
83	Nodule			OFFSIDES
84	Oral candidiasis			SIDER
85	Pain			OFFSIDES SIDER
86	Pancytopenia			SIDER
87	Phlebitis			OFFSIDES
88	Postoperative infection			OFFSIDES
89	Potassium increased			SIDER
90	Protein urine present			SIDER
91	Proteinuria			SIDER
92	Pulmonary Eosinophilia			SIDER
93	Purulent discharge			OFFSIDES
94	Renal cyst			OFFSIDES
95	Retinal Vasculitis			OFFSIDES
96	Rhinitis			SIDER
97	Septic Shock			OFFSIDES
98	Serum sickness-like reaction			SIDER
99	Sinus headache			OFFSIDES
100	Sinusitis			SIDER
101	Sodium decreased			SIDER
102	Somnolence			SIDER
103	Staphylococcal abscess			OFFSIDES
104	Stevens-Johnson Syndrome		25811541	CTD SIDER
105	Stomatitis			SIDER
106	Superinfection			SIDER
107	Sweating			SIDER
108	Tension			SIDER
109	Thirst			SIDER
110	Thrombocytopenia			SIDER
111	Thrombocytosis			SIDER
112	Tinea cruris			OFFSIDES
113	Toxic Epidermal Necrolysis			SIDER
114	Urticaria			SIDER
115	Vaginal Discharge			SIDER
116	Vomiting			SIDER
117	Vulvovaginal mycotic infection			SIDER
118	Weight decreased			SIDER
119	White blood cell count decreased			SIDER
120	pseudomembranous colitis			SIDER

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