MetaADEDB 2.0 @ LMMD
Fondaparinux
(KANJSNBRCNMZMV-ABRZTLGGSA-N)
Structure
SMILES
CO[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1NS(=O)(=O)O)O)O[C@@H]1O[C@@H](C(=O)O)[C@H]([C@@H]([C@H]1OS(=O)(=O)O)O)O[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1NS(=O)(=O)O)OS(=O)(=O)O)O[C@@H]1O[C@H](C(=O)O)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1NS(=O)(=O)O)O)O
Type(s)
Approved; Investigational
ATC code(s)
B01AX05
Molecular Formula:
C31H53N3O49S8
Molecular Weight:
1508.260
Log P:
-3.9310
Hydrogen Bond Acceptor:
52
Hydrogen Bond Donor:
19
TPSA:
872.52
CAS Number(s):
104993-28-4
Synonym(s)
1.
Fondaparinux
2.
Arixtra
3.
Fondaparinux Sodium
4.
Quixidar
External Link(s)
MeSHD000077425
PubChem Compound5282448
49852292
ChEBI61033
CHEMBLCHEMBL1201202
DrugBankDB00569
DrugCentral1236
IUPHAR/BPS Guide to PHARMACOLOGY6819
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1ThrombosisFAERS: 1216148626CTD
SIDER
US FAERS
2Pulmonary EmbolismFAERS: 10US FAERS
3Deep Vein ThrombosisFAERS: 9US FAERS
4ThrombocytopeniaFAERS: 9

View details

CTD
SIDER
US FAERS
5Drug ineffectiveFAERS: 7US FAERS
6Product quality issueFAERS: 7US FAERS
7Injection site bruisingFAERS: 6US FAERS
8Cerebrovascular accidentFAERS: 4US FAERS
9Needle issueFAERS: 4US FAERS
10AstheniaFAERS: 3SIDER
US FAERS
11HypotensionFAERS: 3SIDER
US FAERS
12Incorrect dose administeredFAERS: 3US FAERS
13MalaiseFAERS: 3US FAERS
14DizzinessFAERS: 2SIDER
US FAERS
15Drug administered at inappropriate siteFAERS: 2US FAERS
16Drug dose omissionFAERS: 2US FAERS
17Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
18HeadacheFAERS: 2SIDER
US FAERS
19Heparin-induced thrombocytopeniaFAERS: 2SIDER
US FAERS
20Incorrect product storageFAERS: 2US FAERS
21Memory impairmentFAERS: 2US FAERS
22OverdoseFAERS: 2US FAERS
23PalpitationsFAERS: 2US FAERS
24Product substitution issueFAERS: 2US FAERS
25PruritusFAERS: 2SIDER
US FAERS
26Skin UlcerFAERS: 2US FAERS
27SyncopeFAERS: 2SIDER
US FAERS
28Venous ThrombosisFAERS: 216123915
19129690
CTD
US FAERS
29Abdominal PainFAERS: 1SIDER
US FAERS
30Accidental overdoseFAERS: 1US FAERS
31Adverse eventFAERS: 1US FAERS
32AgitationFAERS: 1US FAERS
33Alanine Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
34AlopeciaFAERS: 1US FAERS
35Anaphylactic shockFAERS: 1SIDER
US FAERS
36AngioedemaFAERS: 1SIDER
US FAERS
37Antiphospholipid SyndromeFAERS: 1US FAERS
38Atrial FibrillationFAERS: 1SIDER
US FAERS
39Back PainFAERS: 1SIDER
US FAERS
40Blood creatinine increasedFAERS: 1US FAERS
41Blood fibrinogen increasedFAERS: 1US FAERS
42Blood lactate dehydrogenase increasedFAERS: 1US FAERS
43Blood urea increasedFAERS: 1US FAERS
44BronchospasmFAERS: 1US FAERS
45Cardiac ArrestFAERS: 1SIDER
US FAERS
46Cardiac TamponadeFAERS: 1SIDER
US FAERS
47Cardiac procedure complicationFAERS: 1US FAERS
48Cerebral PalsyFAERS: 1US FAERS
49Cholecystitis infectiveFAERS: 1US FAERS
50Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
51ConstipationFAERS: 1SIDER
US FAERS
52Creatinine renal clearance decreasedFAERS: 1US FAERS
53Dandy-Walker SyndromeFAERS: 1US FAERS
54Depressed moodFAERS: 1US FAERS
55Device FailureFAERS: 1US FAERS
56DisabilityFAERS: 1US FAERS
57Disseminated Intravascular CoagulationFAERS: 1US FAERS
58Drug administered to patient of inappropriate ageFAERS: 1US FAERS
59Drug cross-reactivityFAERS: 1US FAERS
60Drug ineffective for unapproved indicationFAERS: 1US FAERS
61DysarthriaFAERS: 1US FAERS
62EnteritisFAERS: 1US FAERS
63EpistaxisFAERS: 1SIDER
US FAERS
64FatigueFAERS: 1SIDER
US FAERS
65Fibrin D dimer increasedFAERS: 1US FAERS
66FormicationFAERS: 1US FAERS
67HypersensitivityFAERS: 1SIDER
US FAERS
68Injection Site ReactionFAERS: 1US FAERS
69Injection site painFAERS: 1US FAERS
70Intentional product use issueFAERS: 1US FAERS
71Manufacturing issueFAERS: 1US FAERS
72Maternal exposure during pregnancyFAERS: 1US FAERS
73Megakaryocytes increasedFAERS: 1US FAERS
74MeningiomaFAERS: 1US FAERS
75Muscle strainFAERS: 1US FAERS
76NauseaFAERS: 1SIDER
US FAERS
77NecrosisFAERS: 1US FAERS
78No adverse eventFAERS: 1US FAERS
79Oropharyngeal blisteringFAERS: 1US FAERS
80PainFAERS: 1SIDER
US FAERS
81PancytopeniaFAERS: 1US FAERS
82PhlebitisFAERS: 1US FAERS
83Platelet factor 4 increasedFAERS: 1US FAERS
84PneumoniaFAERS: 1US FAERS
85PneumonitisFAERS: 1US FAERS
86Postoperative thrombosisFAERS: 1US FAERS
87Product contamination physicalFAERS: 1US FAERS
88Product use issueFAERS: 1US FAERS
89Renal ColicFAERS: 1US FAERS
90Respiratory distressFAERS: 1US FAERS
91Right ventricular failureFAERS: 1US FAERS
92Sciatic Nerve PalsyFAERS: 1US FAERS
93SepsisFAERS: 1US FAERS
94Skin necrosisFAERS: 1US FAERS
95Splenic RuptureFAERS: 1US FAERS
96Suspected transmission of an infectious agent via productFAERS: 1US FAERS
97SwellingFAERS: 1US FAERS
98Syringe issueFAERS: 1US FAERS
99Therapy cessationFAERS: 1US FAERS
100ThrombocytosisFAERS: 1SIDER
US FAERS
101Transaminases increasedFAERS: 1US FAERS
102Tumour haemorrhageFAERS: 1US FAERS
103Urinary RetentionFAERS: 1SIDER
US FAERS
104Urinary tract infectionFAERS: 1SIDER
US FAERS
105UrticariaFAERS: 1US FAERS
106Vena cava injuryFAERS: 1US FAERS
107Venous thrombosis limbFAERS: 1US FAERS
108Visual ImpairmentFAERS: 1US FAERS
109intensive careFAERS: 1US FAERS
110Acute Coronary SyndromeSIDER
111AnxietySIDER
112Aspartate Aminotransferase IncreasedSIDER
113Blood and lymphatic system disordersSIDER
114Budd-Chiari Syndrome20160369CTD
115Bullous eruptionSIDER
116Chest PainSIDER
117DermatitisSIDER
118DyspepsiaSIDER
119Embolism and Thrombosis16084352CTD
120Feeling abnormalSIDER
121FlushingSIDER
122GastritisSIDER
123Gastrointestinal PainSIDER
124InfectionSIDER
125InfestationSIDER
126Local reactionSIDER
127MalnutritionSIDER
128Postoperative HemorrhageSIDER
129Procedural site reactionSIDER
130Prothrombin level decreasedSIDER
131PurpuraSIDER
132ShockSIDER
133SomnolenceSIDER
134Surgical site reactionSIDER
135Thrombosis in deviceSIDER
136Vascular purpuraSIDER
137VertigoSIDER
138VomitingSIDER
139Wound discharge increasedSIDER
140nervous system disorderSIDER
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