Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1057
Aptamer sequence: CATGGTGTCAATACTATACCTTTTGCCGATGGTAACAGTTGGTGGTATCC
Target unique ID: Other-41
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_974 | H3.5 | Other | HIV reverse transcriptase (HIV RT) | 37.2 nM | 20 mM Tris-HCl [pH 7.4], 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, and 1 mM CaCl2 | 32298104 |
Structure information of aptamer
| Aptamer Sequence: | CATGGTGTCAATACTATACCTTTTGCCGATGGTAACAGTTGGTGGTATCC |
| The optimal secondary structure in dot-bracket notation: | ..........(((((((..((.(((((...))))).))...))))))).. |
| The centroid secondary structure in dot-bracket notation: | ...(((......)))..(((....(((((.(....)..)))))))).... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_974 | Description | H3.5 |
| Aptamer chemistry | DNA | Length | 50 nt |
| GC content | 44.0% | Molecular weight | 15,396.88 Da |
| Molarity of 1 μg/μl solution | 64.95 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target recognition |
| Sequence | CATGGTGTCAATACTATACCTTTTGCCGATGGTAACAGTTGGTGGTATCC | ||
| Applications | Binding to target proteins | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-41 | Name | HIV reverse transcriptase (HIV RT) |
Activity data
|
No relevant experimental diagram |
Interaction ID | 1057 |
| Target type | Other | |
| Target unique ID | Other-41 | |
| Activity | 37.2 nM | |
| Binding Conditions/Buffer | 20 mM Tris-HCl [pH 7.4], 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, and 1 mM CaCl2 |
|
| Assay | N/A |
|
| PubMed ID | 32298104 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_977 | DNA | CAATCTGCTAAAACTTAAAGCCTATTAATGAAATTGTTAAGGTGGTATCC | |
| Apta_970 | DNA | TTATGTAGCATTTATGAAATTTTTAAATCAATTTACTATTGGTGGTATCC | |
| Apta_973 | DNA | TATGTAATGTTGACGTAATTTATCTCTGTGAGAATAAGCAGGTGGTATCC | |
| Apta_1231 | DNA | ACCACCGGCCCGAGATAGTCTAGACCACTATGTTGTTGTGCTTACTGCTGTGTGGTGTGG | |
| Apta_160 | DNA | CGGTGCAGTGGATACATGCCAGCCGTAGCCATCGTGGATA | |
| Apta_852 | DNA | CATCTGTGTGAAGACTATATGGCGCTCACATATTTCTTTC | |
| Apta_971 | DNA | TAGTCTAGGAACGGTACGATCGTATTCCAAGGACTTTGCTGGTGGTATCC | |
| Apta_975 | DNA | AGACATAGTACATAACCGATCAATGAACATTTAATTAAATGGTGGTATCC | |
| Apta_1087 | DNA | CTTACGACTCAGGCATTTTGCCGGGTAACGAAGTTACTGTCGTAAG | |
| Apta_1097 | DNA | AGGCCCTACACGCCTTTTAGCGAGGGCGTTCCGTGGAGGA | |
| Apta_738 | DNA | ATCGTCTGCTCCGTCCAATACCTGCATATACACTTTGCATGTGGTTTGGTGTGAGGTCGTGC | |
| Apta_740 | DNA | ATCGTCTGCTCCGTCCAATAAACCTGCATAATTTATAAGTCTAGACTGCTGCATTTGGTGTGAGGTCGTGC | |
| Apta_159 | DNA | GCGTGCAGCATGACCACCGATGTCACACTTAATGAGAAT | |
| Apta_267 | DNA | GAGTGCGTAATGGTACGATTTGGGAAGTGGCTTGGGGTGG | |
| Apta_586 | DNA | GGGAGACAAGGAAAATCCTTCAATGAAGTGGGTCGACA | |
| Apta_640 | DNA | CAATGGACCTATTCGAGTACTGAATAGAACAGTCGGCGCTCTGGG | |
| Apta_641 | DNA | TTCAAGACGATGCCTGGCGCGAGTTACACACTTGCATGGAGCTGG | |
| Apta_776 | DNA | AGTGGTCGAACTACACATCCTTGAACTGCGGAATTATCTAC | |
| Apta_835 | DNA | TATGGCGTGGCAAGCTTGGCCCGCTTCTCAAGCATGGTTATCTAC | |
| Apta_853 | DNA | TGACCGAGTGTCTGGTCATTTTCGATGTCTGTTGTTAGGC |
DEV TOOL
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