MetaADEDB 2.0 @ LMMD
Gemifloxacin
(ZRCVYEYHRGVLOC-HYARGMPZSA-N)
Structure
SMILES
NCC1CN(C/C/1=N\OC)c1nc2c(cc1F)c(=O)c(cn2C1CC1)C(=O)O
Type(s)
Approved; Investigational
ATC code(s)
J01MA15
Molecular Formula:
C18H20FN5O4
Molecular Weight:
389.381
Log P:
1.7313
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
2
TPSA:
123.04
CAS Number(s):
175463-14-6; 204519-64-2
Synonym(s)
1.
Gemifloxacin
2.
7-(3-aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)-naphthyridine-3-carboxylic acid
3.
Factive
4.
Gemifloxacin Mesylate
5.
LB 20304
6.
LB-20304
7.
LB20304
8.
SB 265805
9.
SB-265805
10.
SB265805
External Link(s)
MeSHD000077735
PubChem Compound9571107
BindingDB50178917
ChEBI101853
CHEMBLCHEMBL430
DrugBankDB01155
DrugCentral1286
KEGGdr:D08012
Therapeutic Target DatabaseD0VR7W
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1HypersensitivityFAERS: 12US FAERS
2PruritusFAERS: 5SIDER
US FAERS
3Burning sensationFAERS: 2US FAERS
4ErythemaFAERS: 2US FAERS
5FatigueFAERS: 2SIDER
US FAERS
6HeadacheFAERS: 2SIDER
US FAERS
7SwellingFAERS: 2US FAERS
8UrticariaFAERS: 2SIDER
US FAERS
9ArthralgiaFAERS: 1SIDER
US FAERS
10AstheniaFAERS: 1SIDER
US FAERS
11Atrial FibrillationFAERS: 1US FAERS
12Blood glucose decreasedFAERS: 1US FAERS
13BradyphreniaFAERS: 1US FAERS
14Drug administration errorFAERS: 1US FAERS
15Drug dose omissionFAERS: 1US FAERS
16Drug ineffectiveFAERS: 1OFFSIDES
US FAERS
17Impaired driving abilityFAERS: 1US FAERS
18Impaired work abilityFAERS: 1US FAERS
19LethargyFAERS: 1US FAERS
20Lip swellingFAERS: 1US FAERS
21MalaiseFAERS: 1US FAERS
22MeaslesFAERS: 1US FAERS
23Myocardial InfarctionFAERS: 1US FAERS
24MyositisFAERS: 1US FAERS
25Nasal herpesFAERS: 1US FAERS
26Night sweatsFAERS: 1US FAERS
27PainFAERS: 1SIDER
US FAERS
28PalpitationsFAERS: 1SIDER
US FAERS
29Product quality issueFAERS: 1US FAERS
30Skin reactionFAERS: 1US FAERS
31TachycardiaFAERS: 1SIDER
US FAERS
32TremorFAERS: 1SIDER
US FAERS
33Unresponsive to stimuliFAERS: 1US FAERS
34Abdominal PainSIDER
35Abnormal visionSIDER
36AcarodermatitisOFFSIDES
37Acute prerenal failureOFFSIDES
38Acute psychosisOFFSIDES
39AgranulocytosisSIDER
40Alanine Aminotransferase IncreasedSIDER
41Anaphylactic shockSIDER
42AnorexiaSIDER
43AphasiaSIDER
44Aspartate Aminotransferase IncreasedSIDER
45Aspartate aminotransferase decreasedOFFSIDES
46Back PainSIDER
47Band neutrophil percentage increasedOFFSIDES
48Blood albumin decreasedSIDER
49Blood alkaline phosphatase increasedSIDER
50Blood creatine abnormalOFFSIDES
51Blood creatine increasedOFFSIDES
52Blood creatine phosphokinase increasedSIDER
53Blood creatinine increasedSIDER
54Blood lactate dehydrogenase increasedSIDER
55Blood potassium decreasedSIDER
56Blood potassium increasedSIDER
57Blood sodium increasedSIDER
58Blood urea abnormalOFFSIDES
59Blood urea increasedSIDER
60Ca++ increasedSIDER
61Calcium lowSIDER
62Clostridium colitisOFFSIDES
63Clostridium difficile colitisSIDER
64ConstipationSIDER
65Cramps of lower extremitiesSIDER
66Creatine Phosphokinase IncreasedSIDER
67DermatitisSIDER
68DiaphragmalgiaOFFSIDES
69DizzinessSIDER
70DysgeusiaSIDER
71DyspepsiaSIDER
72EczemaSIDER
73EosinophiliaSIDER
74EructationSIDER
75Erythema MultiformeSIDER
76Feeling ColdOFFSIDES
77FlatulenceSIDER
78FlushingSIDER
79Foreign body traumaOFFSIDES
80Gamma-Glutamyltransferase IncreasedSIDER
81GastritisSIDER
82GastroenteritisSIDER
83Gastrointestinal PainSIDER
84GlossitisSIDER
85HyperparathyroidismOFFSIDES
86HyperpigmentationOFFSIDES
87IncoherentOFFSIDES
88Infectious MononucleosisOFFSIDES
89InfestationSIDER
90Lactic dehydrogenase activity increasedSIDER
91LeukopeniaSIDER
92MegacolonSIDER
93Moniliasis genital femaleSIDER
94Muscle strainOFFSIDES
95Musculoskeletal discomfortSIDER
96MyalgiaSIDER
97Myasthenia GravisSIDER
98NauseaSIDER
99NervousnessSIDER
100Neutrophil count decreasedSIDER
101Oropharyngeal swellingOFFSIDES
102PancreatitisSIDER
103PharyngitisSIDER
104PhototoxicitySIDER
105PneumoniaSIDER
106Potassium increasedSIDER
107Potassium lowSIDER
108Protein total decreasedSIDER
109Pulmonary congestionOFFSIDES
110Respiratory arrestSIDER
111RetchingSIDER
112ShockSIDER
113Sodium decreasedSIDER
114Sodium highSIDER
115SomnolenceSIDER
116Stevens-Johnson Syndrome25811541CTD
117StomatitisSIDER
118Supraventricular tachycardiaSIDER
119SyncopeSIDER
120TensionSIDER
121ThrombocytopeniaSIDER
122ThrombocytosisSIDER
123UveitisSIDER
124Vaginal mucosal blisteringSIDER
125VertigoSIDER
126Visual ImpairmentSIDER
127VomitingSIDER
128nervous system disorderSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.