MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

cloxazolam

(ZIXNZOBDFKSQTC-UHFFFAOYSA-N)

Structure

SMILES: O=C1Nc2ccc(cc2C2(N(C1)CCO2)c1ccccc1Cl)Cl
Type(s): Experimental
ATC code(s): N05BA22
Molecular Formula:: C17H14Cl2N2O2
Molecular Weight:: 349.211
Log P:: 3.5547
Hydrogen Bond Acceptor:: 4
Hydrogen Bond Donor:: 1
TPSA:: 41.57
CAS Number(s):: 24166-13-0

Synonym(s)

cloxazolam

10-chloro-11b-(2-chlorophenyl)-2,3,5,6,7,11b-hexahydrobenzo(6,7)-1,4-diazepino(5,4-b)oxazol-6-one

10-chloro-11b-(2-chlorophenyl)-2,3,7,11b(5H)-tetrahydro-oxazolo(3,2-d)(1,4)benzodiazepine-6-one

CS 370

MT 14-411

Olcadil

former CAS registry number of cloxazolam

External Link(s)

MeSH	C005522
PubChem Compound	2816
BindingDB	220121
ChEBI	31426
CHEMBL	CHEMBL2107254
DrugBank	DB01553
DrugCentral	721
KEGG	dr:D01268

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal Compartment Syndrome		OFFSIDES
2	Abdominal Infection		OFFSIDES
3	Abdominal Pain		OFFSIDES
4	Abdominal discomfort		OFFSIDES
5	Abdominal wall infection		OFFSIDES
6	Abnormal vision		OFFSIDES
7	Adverse event		OFFSIDES
8	Altered state of consciousness		OFFSIDES
9	Amnesia		OFFSIDES
10	Andropause		OFFSIDES
11	Anorexia		OFFSIDES
12	Anxiety		OFFSIDES
13	Apathy		OFFSIDES
14	Apnea		OFFSIDES
15	Arthritis		OFFSIDES
16	Asthenia		OFFSIDES
17	Ataxia		OFFSIDES
18	Atrial Flutter		OFFSIDES
19	Aura		OFFSIDES
20	Bladder discomfort		OFFSIDES
21	Blood Glucose		OFFSIDES
22	Blood creatine increased		OFFSIDES
23	Blood creatine phosphokinase increased		OFFSIDES
24	Blood ketone body present		OFFSIDES
25	Blood potassium increased		OFFSIDES
26	Blood pressure fluctuation		OFFSIDES
27	Blood testosterone increased		OFFSIDES
28	Blurred vision		OFFSIDES
29	Bradycardia		OFFSIDES
30	Brain Hypoxia		OFFSIDES
31	Breast Feeding		OFFSIDES
32	Cell marker increased		OFFSIDES
33	Cold sweat		OFFSIDES
34	Conjunctival deposit		OFFSIDES
35	Crying		OFFSIDES
36	Cytomegalovirus enterocolitis		OFFSIDES
37	Dengue Fever		OFFSIDES
38	Depressed Level of Consciousness		OFFSIDES
39	Depressed mood		OFFSIDES
40	Depressive disorder	10967655	CTD
41	Diarrhea		OFFSIDES
42	Disseminated Intravascular Coagulation		OFFSIDES
43	Dizziness		OFFSIDES
44	Drowsiness		OFFSIDES
45	Drug addict		OFFSIDES
46	Drug administration error		OFFSIDES
47	Drug exposure during pregnancy		OFFSIDES
48	Drug ineffective		OFFSIDES
49	Drug withdrawal headache		OFFSIDES
50	Dry skin		OFFSIDES
51	Dysgeusia		OFFSIDES
52	Dyslalia		OFFSIDES
53	Dyspepsia		OFFSIDES
54	Dysthymic Disorder		OFFSIDES
55	Dysuria		OFFSIDES
56	Elevated mood		OFFSIDES
57	Empyema		OFFSIDES
58	Enterocolitis		OFFSIDES
59	Enterocutaneous Fistula		OFFSIDES
60	Epilepsy		OFFSIDES
61	Epistaxis		OFFSIDES
62	Eyelids pruritus		OFFSIDES
63	Fatigue		OFFSIDES
64	Fatty Liver		OFFSIDES
65	Fistula discharge		OFFSIDES
66	Flatulence		OFFSIDES
67	Formication		OFFSIDES
68	Gamma-Glutamyltransferase Increased		OFFSIDES
69	Gastric Dilatation		OFFSIDES
70	Gastric Lavage		OFFSIDES
71	Gastroenteritis		OFFSIDES
72	Glossoptosis		OFFSIDES
73	Head titubation		OFFSIDES
74	Helicobacter pylori identification test positive		OFFSIDES
75	Hordeolum		OFFSIDES
76	House dust allergy		OFFSIDES
77	Hypokinesia		OFFSIDES
78	Infected epidermal cyst		OFFSIDES
79	Infusion site mobility decreased		OFFSIDES
80	Intention tremor		OFFSIDES
81	Intentional misuse		OFFSIDES
82	Intubation		OFFSIDES
83	Laziness		OFFSIDES
84	Lung consolidation		OFFSIDES
85	Lupus encephalitis		OFFSIDES
86	Metabolic acidosis		OFFSIDES
87	Multiple Sclerosis		OFFSIDES
88	Multiple sclerosis relapse		OFFSIDES
89	Muscle Weakness		OFFSIDES
90	Myoglobin blood increased		OFFSIDES
91	Nasopharyngitis		OFFSIDES
92	Nausea		OFFSIDES
93	Negative thoughts		OFFSIDES
94	Nephrogenic Diabetes Insipidus		OFFSIDES
95	Nervous tension		OFFSIDES
96	Neuroleptic Malignant Syndrome		OFFSIDES
97	Neutrophil count decreased		OFFSIDES
98	Nocturia		OFFSIDES
99	Nystagmus		OFFSIDES
100	Ocular icterus		OFFSIDES
101	Overdose		OFFSIDES
102	Oxygen supplementation		OFFSIDES
103	Pain of skin		OFFSIDES
104	Pain		OFFSIDES
105	Pallor		OFFSIDES
106	Periarthritis		OFFSIDES
107	Phlebitis		OFFSIDES
108	Pneumocystis jiroveci pneumonia		OFFSIDES
109	Productive Cough		OFFSIDES
110	Progesterone increased		OFFSIDES
111	Quadriplegia		OFFSIDES
112	Renal Artery Stenosis		OFFSIDES
113	Rhinitis		OFFSIDES
114	Splenitis		OFFSIDES
115	Stress		OFFSIDES
116	Sudden death		OFFSIDES
117	Urine ketone body present		OFFSIDES
118	Uterine Polyp		OFFSIDES
119	Visual disturbance		OFFSIDES
120	Water Intoxication		OFFSIDES
121	Weight Gain		OFFSIDES

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