MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Promazine

(ZGUGWUXLJSTTMA-UHFFFAOYSA-N)

Structure

SMILES: CN(CCCN1c2ccccc2Sc2c1cccc2)C
Type(s): Approved; Vet_approved
ATC code(s): N05AA03
Molecular Formula:: C17H20N2S
Molecular Weight:: 284.419
Log P:: 4.3060
Hydrogen Bond Acceptor:: 2
Hydrogen Bond Donor:: 0
TPSA:: 31.78
CAS Number(s):: 53-60-1; 58-40-2

Synonym(s)

Promazine

Promazine Hydrochloride

Protactyl

Sinophenin

Sparine

Hydrochloride, Promazine

External Link(s)

MeSH	D011395
PubChem Compound	4926
BindingDB	50017717 67545
ChEBI	8459
CHEMBL	CHEMBL564
DrugBank	DB00420
DrugCentral	2284
IUPHAR/BPS Guide to PHARMACOLOGY	7281
KEGG	cpd:C07379 dr:D08430
Therapeutic Target Database	D00NAX
ZINC	10402

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Akinesia		OFFSIDES
2	Amniotic fluid volume decreased		OFFSIDES
3	Amphetamines		OFFSIDES
4	Antisocial Personality Disorder		OFFSIDES
5	Aphonia	4405372	CTD
6	Apnea	6067266	CTD
7	Ataxia		OFFSIDES
8	Athetosis	4144147	CTD OFFSIDES
9	Atrial tachycardia		OFFSIDES
10	Basal ganglion degeneration		OFFSIDES
11	Blepharospasm		OFFSIDES
12	Blood pressure fluctuation		OFFSIDES
13	Cholangiolitis		OFFSIDES
14	Congenital cystic kidney disease		OFFSIDES
15	Decreased Libido		OFFSIDES
16	Depressed mood		OFFSIDES
17	Diplopia		OFFSIDES
18	Drowsiness		OFFSIDES
19	Drug exposure during pregnancy		OFFSIDES
20	Drug toxicity		OFFSIDES
21	Drug withdrawal convulsions		OFFSIDES
22	Duodenitis		OFFSIDES
23	Dysphemia		OFFSIDES
24	Dystonia		OFFSIDES
25	Emotional distress		OFFSIDES
26	Epilepsy		OFFSIDES
27	Erosive gastritis		OFFSIDES
28	Fatigue		OFFSIDES
29	Foaming at mouth		OFFSIDES
30	Galactorrhea		OFFSIDES
31	Granulocytosis		OFFSIDES
32	Hyperemesis Gravidarum	6017500	CTD
33	Hyperventilation		OFFSIDES
34	Incontinence		OFFSIDES
35	Intention tremor		OFFSIDES
36	Lethargy		OFFSIDES
37	Leukoencephalopathy		OFFSIDES
38	Long QT Syndrome		OFFSIDES
39	Lysosomal Storage Diseases	28551711	CTD
40	Motor retardation		OFFSIDES
41	Multiple drug overdose intentional		OFFSIDES
42	Mutism		OFFSIDES
43	Myocardial Ischemia	12649773	CTD
44	Neuroleptic Malignant Syndrome		OFFSIDES
45	Oropharyngeal spasm		OFFSIDES
46	Overdose		OFFSIDES
47	Paranoia		OFFSIDES
48	Poor quality sleep		OFFSIDES
49	Psychoses, Substance-Induced	1669614	CTD
50	Renal dysplasia		OFFSIDES
51	Rhabdomyolysis		OFFSIDES
52	Schizophrenia		OFFSIDES
53	Sopor		OFFSIDES
54	Starvation		OFFSIDES
55	Thrombophlebitis		OFFSIDES
56	Tremor	9681765	CTD
57	Ventricular Fibrillation		OFFSIDES
58	Violence-related symptom		OFFSIDES
59	Visual disturbance		OFFSIDES

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