Desmopressin acetate trihydrate
(YNKFCNRZZPFMEX-UHFFFAOYSA-N)
Structure
- SMILES
- NC(=O)CC1NC(=O)C(CCC(=O)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)CCSSCC(NC1=O)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)N)CCCN=C(N)N)Cc1ccc(cc1)O.CC(=O)O.O.O.O
- Molecular Formula:
- C48H74N14O17S2
- Molecular Weight:
- 1183.310
- Log P:
- 1.4215
- Hydrogen Bond Acceptor:
- 33
- Hydrogen Bond Donor:
- 17
- TPSA:
- 553.5
- CAS Number(s):
- 62357-86-2
Synonym(s)
1.
Desmopressin acetate trihydrate
External Link(s)
| PubChem Compound | 64759 |
| CHEMBL | CHEMBL2138698 |
| KEGG | dr:D02235 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Headache | FAERS: 62 | US FAERS | |
| 2 | Flushing | FAERS: 49 | US FAERS | |
| 3 | Epistaxis | FAERS: 41 | US FAERS | |
| 4 | Drug ineffective | FAERS: 32 | US FAERS | |
| 5 | Dizziness | FAERS: 17 | US FAERS | |
| 6 | Product use in unapproved indication | FAERS: 15 | US FAERS | |
| 7 | Fatigue | FAERS: 12 | US FAERS | |
| 8 | Somnolence | FAERS: 10 | US FAERS | |
| 9 | Nausea | FAERS: 9 | US FAERS | |
| 10 | Feeling abnormal | FAERS: 8 | US FAERS | |
| 11 | Erythema | FAERS: 7 | US FAERS | |
| 12 | Malaise | FAERS: 7 | US FAERS | |
| 13 | Menorrhagia | FAERS: 7 | US FAERS | |
| 14 | Lethargy | FAERS: 5 | US FAERS | |
| 15 | No adverse event | FAERS: 5 | US FAERS | |
| 16 | Vomiting | FAERS: 5 | US FAERS | |
| 17 | Accidental overdose | FAERS: 4 | US FAERS | |
| 18 | Anxiety | FAERS: 4 | US FAERS | |
| 19 | Chest discomfort | FAERS: 4 | US FAERS | |
| 20 | Disorientation | FAERS: 4 | US FAERS | |
| 21 | Lip swelling | FAERS: 4 | US FAERS | |
| 22 | Product use issue | FAERS: 4 | US FAERS | |
| 23 | Arthralgia | FAERS: 3 | US FAERS | |
| 24 | Hypersensitivity | FAERS: 3 | US FAERS | |
| 25 | Myalgia | FAERS: 3 | US FAERS | |
| 26 | Thirst | FAERS: 3 | US FAERS | |
| 27 | Urticaria | FAERS: 3 | US FAERS | |
| 28 | Water Intoxication | FAERS: 3 | US FAERS | |
| 29 | Amnesia | FAERS: 2 | US FAERS | |
| 30 | Arthritis | FAERS: 2 | US FAERS | |
| 31 | Circumstance or information capable of leading to medication error | FAERS: 2 | US FAERS | |
| 32 | Dehydration | FAERS: 2 | US FAERS | |
| 33 | Expired product administered | FAERS: 2 | US FAERS | |
| 34 | Feeling jittery | FAERS: 2 | US FAERS | |
| 35 | Joint injury | FAERS: 2 | US FAERS | |
| 36 | Nasal discomfort | FAERS: 2 | US FAERS | |
| 37 | Pain | FAERS: 2 | US FAERS | |
| 38 | Paranoia | FAERS: 2 | US FAERS | |
| 39 | Personality Change | FAERS: 2 | US FAERS | |
| 40 | Pneumonia | FAERS: 2 | US FAERS | |
| 41 | Post procedural complication | FAERS: 2 | US FAERS | |
| 42 | Product quality issue | FAERS: 2 | US FAERS | |
| 43 | Sluggishness | FAERS: 2 | US FAERS | |
| 44 | Specific gravity urine abnormal | FAERS: 2 | US FAERS | |
| 45 | Unevaluable event | FAERS: 2 | US FAERS | |
| 46 | Akinesia | FAERS: 1 | US FAERS | |
| 47 | Alopecia | FAERS: 1 | US FAERS | |
| 48 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 49 | Back Pain | FAERS: 1 | US FAERS | |
| 50 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 51 | Blood sodium increased | FAERS: 1 | US FAERS | |
| 52 | Blood urine present | FAERS: 1 | US FAERS | |
| 53 | Bronchitis | FAERS: 1 | US FAERS | |
| 54 | Cataract operation | FAERS: 1 | US FAERS | |
| 55 | Chest Pain | FAERS: 1 | US FAERS | |
| 56 | Electrolyte depletion | FAERS: 1 | US FAERS | |
| 57 | Exposure during breast feeding | FAERS: 1 | US FAERS | |
| 58 | Food Allergy | FAERS: 1 | US FAERS | |
| 59 | Glaucoma surgery | FAERS: 1 | US FAERS | |
| 60 | Glaucoma | FAERS: 1 | US FAERS | |
| 61 | Hypotension | FAERS: 1 | US FAERS | |
| 62 | Impaired work ability | FAERS: 1 | US FAERS | |
| 63 | Infection | FAERS: 1 | US FAERS | |
| 64 | Influenza | FAERS: 1 | US FAERS | |
| 65 | Intentional self-injury | FAERS: 1 | US FAERS | |
| 66 | Irritable Bowel Syndrome | FAERS: 1 | US FAERS | |
| 67 | Joint swelling | FAERS: 1 | US FAERS | |
| 68 | Laceration | FAERS: 1 | US FAERS | |
| 69 | Limb discomfort | FAERS: 1 | US FAERS | |
| 70 | Limb injury | FAERS: 1 | US FAERS | |
| 71 | Lymphoma | FAERS: 1 | US FAERS | |
| 72 | Medication Error | FAERS: 1 | US FAERS | |
| 73 | Muscle Fatigue | FAERS: 1 | US FAERS | |
| 74 | Overdose | FAERS: 1 | US FAERS | |
| 75 | Parent-child problem | FAERS: 1 | US FAERS | |
| 76 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 77 | Petechiae | FAERS: 1 | US FAERS | |
| 78 | Product supply issue | FAERS: 1 | US FAERS | |
| 79 | Pruritus | FAERS: 1 | US FAERS | |
| 80 | Renal pain | FAERS: 1 | US FAERS | |
| 81 | Sepsis | FAERS: 1 | US FAERS | |
| 82 | Suture insertion | FAERS: 1 | US FAERS | |
| 83 | Swelling | FAERS: 1 | US FAERS | |
| 84 | Syncope | FAERS: 1 | US FAERS | |
| 85 | Therapeutic product ineffective | FAERS: 1 | US FAERS | |
| 86 | Therapeutic response unexpected with drug substitution | FAERS: 1 | US FAERS | |
| 87 | colonoscopy | FAERS: 1 | US FAERS |
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