MetaADEDB 2.0 @ LMMD
Rilpivirine
(YIBOMRUWOWDFLG-ONEGZZNKSA-N)
Structure
SMILES
N#C/C=C/c1cc(C)c(c(c1)C)Nc1ccnc(n1)Nc1ccc(cc1)C#N
Type(s)
Approved
ATC code(s)
J05AG05; J05AR08; J05AR19; J05AR21
Molecular Formula:
C22H18N6
Molecular Weight:
366.419
Log P:
5.1351
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
97.42
CAS Number(s):
500287-72-9
Synonym(s)
1.
Rilpivirine
2.
R278474
3.
Rilpivirine HCl
4.
Rilpivirine Hydrochloride
5.
TMC 278
6.
TMC-278
7.
TMC278
8.
278, TMC
9.
HCl, Rilpivirine
10.
Hydrochloride, Rilpivirine
External Link(s)
MeSHD000068696
PubChem Compound6451164
BindingDB222178
ChEBI68606
CHEMBLCHEMBL175691
DrugBankDB08864
DrugCentral4174
KEGGdr:D09720
Therapeutic Target DatabaseD0T6WN
D09KSE
ZINC1554274
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug dose omissionFAERS: 6US FAERS
2Adverse eventFAERS: 5US FAERS
3Product packaging quantity issueFAERS: 5US FAERS
4Incorrect product storageFAERS: 3US FAERS
5Wrong technique in product usage processFAERS: 3US FAERS
6Abdominal discomfortFAERS: 2SIDER
US FAERS
7AnxietyFAERS: 2SIDER
US FAERS
8AphagiaFAERS: 2US FAERS
9AppendicitisFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
10ArthritisFAERS: 2US FAERS
11Chest PainFAERS: 2US FAERS
12Drug ineffectiveFAERS: 2US FAERS
13Drug prescribing errorFAERS: 2US FAERS
14IncontinenceFAERS: 2US FAERS
15MalaiseFAERS: 2US FAERS
16OsteoporosisFAERS: 2US FAERS
17Viral load increasedFAERS: 2US FAERS
18Virologic failureFAERS: 2US FAERS
19ArthralgiaFAERS: 1US FAERS
20Aspartate Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
21Atrial FibrillationFAERS: 1US FAERS
22Blood creatinine increasedFAERS: 1SIDER
US FAERS
23CD4 Lymphocytes DecreasedFAERS: 1US FAERS
24Cerebral InfarctionFAERS: 1US FAERS
25Cerebrovascular accidentFAERS: 1US FAERS
26ChromaturiaFAERS: 1US FAERS
27DisorientationFAERS: 1US FAERS
28DizzinessFAERS: 1SIDER
US FAERS
29Drug dispensing errorFAERS: 1US FAERS
30Drug resistanceFAERS: 1US FAERS
31Drug screen positiveFAERS: 1US FAERS
32EosinophiliaFAERS: 1US FAERS
33EructationFAERS: 1US FAERS
34FatigueFAERS: 1SIDER
US FAERS
35GastrectomyFAERS: 1US FAERS
36Gene MutationFAERS: 1US FAERS
37Gestational DiabetesFAERS: 1US FAERS
38HeadacheFAERS: 1SIDER
US FAERS
39HepatotoxicityFAERS: 1SIDER
US FAERS
40HypotensionFAERS: 1US FAERS
41Intentional product misuseFAERS: 1US FAERS
42MyalgiaFAERS: 1US FAERS
43Night sweatsFAERS: 1US FAERS
44PainFAERS: 1US FAERS
45PancreatitisFAERS: 1US FAERS
46PancytopeniaFAERS: 1US FAERS
47Physical product label issueFAERS: 1US FAERS
48PneumoniaFAERS: 1US FAERS
49Product quality issueFAERS: 1US FAERS
50Product size issueFAERS: 1US FAERS
51Product storage errorFAERS: 1US FAERS
52Psychiatric symptomFAERS: 1US FAERS
53Suspected counterfeit productFAERS: 1US FAERS
54TuberculosisFAERS: 1US FAERS
55Urinary tract infectionFAERS: 1US FAERS
56VomitingFAERS: 1SIDER
US FAERS
57White blood cell count decreasedFAERS: 1SIDER
US FAERS
58Wrong technique in drug usage processFAERS: 1US FAERS
59intensive careFAERS: 1US FAERS
60nervous system disorderFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
61Abdominal PainSIDER
62Alanine Aminotransferase IncreasedSIDER
63AstheniaSIDER
64Blood and lymphatic system disordersSIDER
65Blood cholesterol increasedSIDER
66Buffalo humpSIDER
67CholecystitisSIDER
68CholelithiasisSIDER
69Creatinine increasedSIDER
70Depressed moodSIDER
71Depressive disorderSIDER
72DermatitisSIDER
73DyspepsiaCanada Vigilance: 1Canada Vigilance
74Dysthymic DisorderSIDER
75Gastrointestinal PainSIDER
76GlomerulonephritisSIDER
77Hepatitis BSIDER
78Hepatitis CSIDER
79Hypertrophy of BreastSIDER
80InfectionSIDER
81InflammationSIDER
82Lipase increasedSIDER
83Lipodystrophy acquiredSIDER
84LipodystrophySIDER
85LipohypertrophySIDER
86Low density lipoprotein increasedSIDER
87MalnutritionSIDER
88NauseaSIDER
89NephrolithiasisSIDER
90Nephrotic SyndromeSIDER
91SomnolenceSIDER
92Transaminases increasedSIDER
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