cyclobenzaprine
(VXEAYBOGHINOKW-UHFFFAOYSA-N)
Structure
- SMILES
- CN(CCC=C1c2ccccc2C=Cc2c1cccc2)C.Cl
- Molecular Formula:
- C20H22ClN
- Molecular Weight:
- 311.848
- Log P:
- 5.3558
- Hydrogen Bond Acceptor:
- 1
- Hydrogen Bond Donor:
- 1
- TPSA:
- 3.24
- CAS Number(s):
- 6202-23-9
Synonym(s)
1.
cyclobenzaprine
2.
Flexeril
3.
Lisseril
4.
cyclobenzaprine hydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 29 | US FAERS | |
| 2 | Somnolence | FAERS: 24 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Dizziness | FAERS: 16 | US FAERS | |
| 4 | Fatigue | FAERS: 13 | US FAERS | |
| 5 | Nausea | FAERS: 13 | US FAERS | |
| 6 | Headache | FAERS: 12 | US FAERS | |
| 7 | Pain | FAERS: 12 | US FAERS | |
| 8 | Asthenia | FAERS: 9 | US FAERS | |
| 9 | Anxiety | FAERS: 8 | US FAERS | |
| 10 | Feeling abnormal | FAERS: 8 | US FAERS | |
| 11 | Amnesia | FAERS: 7 | US FAERS | |
| 12 | Constipation | FAERS: 7 | US FAERS | |
| 13 | Anger | FAERS: 6 | US FAERS | |
| 14 | Drug abuse | FAERS: 6 | US FAERS | |
| 15 | Hypersensitivity | FAERS: 6 | US FAERS | |
| 16 | Lethargy | FAERS: 6 | US FAERS | |
| 17 | Palpitations | FAERS: 6 | US FAERS | |
| 18 | Pharmaceutical product complaint | FAERS: 6 | US FAERS | |
| 19 | Pruritus | FAERS: 6 | US FAERS | |
| 20 | Tremor | FAERS: 6 | US FAERS | |
| 21 | Chest Pain | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 22 | Incorrect dose administered | FAERS: 5 | US FAERS | |
| 23 | Incorrect drug administration duration | FAERS: 5 | US FAERS | |
| 24 | Malaise | FAERS: 5 | US FAERS | |
| 25 | Vomiting | FAERS: 5 | US FAERS | |
| 26 | Abdominal Pain | FAERS: 4 | US FAERS | |
| 27 | Atrial Fibrillation | FAERS: 4 | US FAERS | |
| 28 | Cerebrovascular accident | FAERS: 4 | US FAERS | |
| 29 | Chest discomfort | FAERS: 4 | US FAERS | |
| 30 | Inappropriate schedule of drug administration | FAERS: 4 | US FAERS | |
| 31 | Mental status changes | FAERS: 4 | US FAERS | |
| 32 | Nystagmus | FAERS: 4 | US FAERS | |
| 33 | Overdose | FAERS: 4 | US FAERS | |
| 34 | Restless Legs Syndrome | FAERS: 4 | US FAERS | |
| 35 | Toxicity to various agents | FAERS: 4 | US FAERS | |
| 36 | Abasia | FAERS: 3 | US FAERS | |
| 37 | Arthralgia | FAERS: 3 | US FAERS | |
| 38 | Back Pain | FAERS: 3 | US FAERS | |
| 39 | Discomfort | FAERS: 3 | US FAERS | |
| 40 | Drug prescribing error | FAERS: 3 | US FAERS | |
| 41 | Drug toxicity | FAERS: 3 | US FAERS | |
| 42 | Erythema Multiforme | FAERS: 3 | US FAERS | |
| 43 | Erythema | FAERS: 3 | US FAERS | |
| 44 | Formication | FAERS: 3 | US FAERS | |
| 45 | Hypersomnia | FAERS: 3 | US FAERS | |
| 46 | Joint swelling | FAERS: 3 | US FAERS | |
| 47 | Medication Error | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 48 | Memory impairment | FAERS: 3 | US FAERS | |
| 49 | Myalgia | FAERS: 3 | US FAERS | |
| 50 | Myoclonus | FAERS: 3 | US FAERS | |
| 51 | Restlessness | FAERS: 3 | US FAERS | |
| 52 | Syncope | FAERS: 3 | US FAERS | |
| 53 | Tachycardia | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 54 | Torticollis | FAERS: 3 | US FAERS | |
| 55 | Urticaria | FAERS: 3 | US FAERS | |
| 56 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 57 | Accidental exposure | FAERS: 2 | US FAERS | |
| 58 | Activities of daily living impaired | FAERS: 2 | US FAERS | |
| 59 | Adverse event | FAERS: 2 | US FAERS | |
| 60 | Cardiac Arrest | FAERS: 2 | US FAERS | |
| 61 | Completed Suicide | FAERS: 2 | US FAERS | |
| 62 | Crying | FAERS: 2 | US FAERS | |
| 63 | Delirium | FAERS: 2 | US FAERS | |
| 64 | Drug dispensing error | FAERS: 2 | US FAERS | |
| 65 | Drug screen false positive | FAERS: 2 | US FAERS | |
| 66 | Dysarthria | FAERS: 2 | US FAERS | |
| 67 | Impaired driving ability | FAERS: 2 | US FAERS | |
| 68 | Incoherent | FAERS: 2 | US FAERS | |
| 69 | Macular degeneration | FAERS: 2 | US FAERS | |
| 70 | Myocardial Infarction | FAERS: 2 | US FAERS | |
| 71 | Nasopharyngitis | FAERS: 2 | US FAERS | |
| 72 | Nervousness | FAERS: 2 | US FAERS | |
| 73 | Neuroleptic Malignant Syndrome | FAERS: 2 | US FAERS | |
| 74 | Peripheral swelling | FAERS: 2 | US FAERS | |
| 75 | Photophobia | FAERS: 2 | US FAERS | |
| 76 | Product use issue | FAERS: 2 | US FAERS | |
| 77 | Protein total increased | FAERS: 2 | US FAERS | |
| 78 | Reaction to drug excipients | FAERS: 2 | US FAERS | |
| 79 | Screaming | FAERS: 2 | US FAERS | |
| 80 | Suicide attempt | FAERS: 2 | US FAERS | |
| 81 | Therapeutic response unexpected | FAERS: 2 | US FAERS | |
| 82 | Tinnitus | FAERS: 2 | US FAERS | |
| 83 | Unevaluable event | FAERS: 2 | US FAERS | |
| 84 | Urinary Retention | FAERS: 2 | US FAERS | |
| 85 | VIIth nerve paralysis | FAERS: 2 | US FAERS | |
| 86 | Wrong drug administered | FAERS: 2 | US FAERS | |
| 87 | nervous system disorder | FAERS: 2 | US FAERS | |
| 88 | Accidental drug intake by child | FAERS: 1 | US FAERS | |
| 89 | Age indeterminate myocardial infarction | FAERS: 1 | US FAERS | |
| 90 | Ageusia | FAERS: 1 | US FAERS | |
| 91 | Agitation | FAERS: 1 | US FAERS | |
| 92 | Allergic reaction to excipient | FAERS: 1 | US FAERS | |
| 93 | Angle Closure Glaucoma | FAERS: 1 | US FAERS | |
| 94 | Anuria | FAERS: 1 | US FAERS | |
| 95 | Aphasia | FAERS: 1 | US FAERS | |
| 96 | Asthenopia | FAERS: 1 | US FAERS | |
| 97 | Asthma | FAERS: 1 | US FAERS | |
| 98 | Bedridden | FAERS: 1 | US FAERS | |
| 99 | Blepharospasm | FAERS: 1 | US FAERS | |
| 100 | Blindness | FAERS: 1 | US FAERS | |
| 101 | Blood cholesterol increased | FAERS: 1 | US FAERS | |
| 102 | Burning sensation | FAERS: 1 | US FAERS | |
| 103 | Cardiac Flutter | FAERS: 1 | US FAERS | |
| 104 | Cellulitis | FAERS: 1 | US FAERS | |
| 105 | Chills | FAERS: 1 | US FAERS | |
| 106 | Cold sweat | FAERS: 1 | US FAERS | |
| 107 | Dehydration | FAERS: 1 | US FAERS | |
| 108 | Diabetes Mellitus | FAERS: 1 | US FAERS | |
| 109 | Disorientation | FAERS: 1 | US FAERS | |
| 110 | Drug administration error | FAERS: 1 | US FAERS | |
| 111 | Drug dose omission | FAERS: 1 | US FAERS | |
| 112 | Drug effect delayed | FAERS: 1 | US FAERS | |
| 113 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 114 | Drug label confusion | FAERS: 1 | US FAERS | |
| 115 | Dysgeusia | FAERS: 1 | US FAERS | |
| 116 | Dysphemia | FAERS: 1 | US FAERS | |
| 117 | Dysphonia | FAERS: 1 | US FAERS | |
| 118 | Dysuria | FAERS: 1 | US FAERS | |
| 119 | Emotional disorder | FAERS: 1 | US FAERS | |
| 120 | Emotional distress | FAERS: 1 | US FAERS | |
| 121 | Epinephrine increased | FAERS: 1 | US FAERS | |
| 122 | Erectile dysfunction | FAERS: 1 | US FAERS | |
| 123 | Expired product administered | FAERS: 1 | US FAERS | |
| 124 | Eye pain | FAERS: 1 | US FAERS | |
| 125 | False positive investigation result | FAERS: 1 | US FAERS | |
| 126 | Feeling Cold | FAERS: 1 | US FAERS | |
| 127 | Feeling jittery | FAERS: 1 | US FAERS | |
| 128 | Flank Pain | FAERS: 1 | US FAERS | |
| 129 | Flatulence | FAERS: 1 | US FAERS | |
| 130 | Frustration | FAERS: 1 | US FAERS | |
| 131 | Glaucoma | FAERS: 1 | US FAERS | |
| 132 | Gluten sensitivity | FAERS: 1 | US FAERS | |
| 133 | Hemiparesis | FAERS: 1 | US FAERS | |
| 134 | Hostility | FAERS: 1 | US FAERS | |
| 135 | Inflammation | FAERS: 1 | US FAERS | |
| 136 | Intentional drug misuse | FAERS: 1 | US FAERS | |
| 137 | Intentional misuse | FAERS: 1 | US FAERS | |
| 138 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 139 | Intentional self-injury | FAERS: 1 | US FAERS | |
| 140 | Intercepted drug administration error | FAERS: 1 | US FAERS | |
| 141 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 142 | Joint stiffness | FAERS: 1 | US FAERS | |
| 143 | Mental impairment | FAERS: 1 | US FAERS | |
| 144 | Mood swings | FAERS: 1 | US FAERS | |
| 145 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 146 | Musculoskeletal discomfort | FAERS: 1 | US FAERS | |
| 147 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 148 | Myocarditis | FAERS: 1 | US FAERS | |
| 149 | Myoclonic Epilepsy | FAERS: 1 | US FAERS | |
| 150 | Neck Pain | FAERS: 1 | US FAERS | |
| 151 | Non-cardiac chest pain | FAERS: 1 | US FAERS | |
| 152 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 153 | Personality Change | FAERS: 1 | US FAERS | |
| 154 | Physical abuse | FAERS: 1 | US FAERS | |
| 155 | Poor quality drug administered | FAERS: 1 | US FAERS | |
| 156 | Presyncope | FAERS: 1 | US FAERS | |
| 157 | Product quality issue | FAERS: 1 | US FAERS | |
| 158 | Product substitution issue | FAERS: 1 | US FAERS | |
| 159 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 160 | Reaction to excipient | FAERS: 1 | US FAERS | |
| 161 | Rectal discharge | FAERS: 1 | US FAERS | |
| 162 | Retching | FAERS: 1 | US FAERS | |
| 163 | Scotoma | FAERS: 1 | US FAERS | |
| 164 | Sinusitis | FAERS: 1 | US FAERS | |
| 165 | Skin laceration | FAERS: 1 | US FAERS | |
| 166 | Sluggishness | FAERS: 1 | US FAERS | |
| 167 | Somnambulism | FAERS: 1 | US FAERS | |
| 168 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 169 | Stupor | FAERS: 1 | US FAERS | |
| 170 | Sudden Cardiac Death | FAERS: 1 | US FAERS | |
| 171 | Therapeutic product contamination | FAERS: 1 | US FAERS | |
| 172 | Therapy cessation | FAERS: 1 | US FAERS | |
| 173 | Thirst | FAERS: 1 | US FAERS | |
| 174 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 175 | Trismus | FAERS: 1 | US FAERS | |
| 176 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 177 | Upper respiratory tract congestion | FAERS: 1 | US FAERS | |
| 178 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 179 | Urine flow decreased | FAERS: 1 | US FAERS | |
| 180 | Vertigo | FAERS: 1 | US FAERS | |
| 181 | Victim of child abuse | FAERS: 1 | US FAERS | |
| 182 | Visual Impairment | FAERS: 1 | US FAERS |
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