MetaADEDB 2.0 @ LMMD
Asenapine
(VSWBSWWIRNCQIJ-GJZGRUSLSA-N)
Structure
SMILES
Clc1ccc2c(c1)[C@@H]1CN(C[C@H]1c1c(O2)cccc1)C
Molecular Formula:
C17H16ClNO
Molecular Weight:
285.768
Log P:
4.1964
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
12.47
CAS Number(s):
65576-45-6
Synonym(s)
1.
Asenapine
2.
5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3-6,7)oxepino(4,5-c)pyrrole
3.
ORG 5222
4.
ORG-5222
5.
asenapine maleate
6.
saphris
External Link(s)
MeSHC522667
PubChem Compound3036780
BindingDB50428890
50445613
ChEBI71256
CHEMBLCHEMBL1201756
ZINC4893
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AgitationFAERS: 6SIDER
US FAERS
2Chest discomfortFAERS: 4US FAERS
3DizzinessFAERS: 3SIDER
US FAERS
4Drug dose omissionFAERS: 3US FAERS
5DysarthriaFAERS: 3SIDER
US FAERS
6HypotensionFAERS: 3SIDER
US FAERS
7CamptocormiaFAERS: 2US FAERS
8Choking sensationFAERS: 2US FAERS
9Feeling abnormalFAERS: 2US FAERS
10NauseaFAERS: 2SIDER
US FAERS
11OverdoseFAERS: 2US FAERS
12Psychiatric decompensationFAERS: 2US FAERS
13Respiratory distressFAERS: 2US FAERS
14TrismusFAERS: 2US FAERS
15Unevaluable eventFAERS: 2US FAERS
16Acute psychosisFAERS: 1US FAERS
17Acute respiratory failureFAERS: 1US FAERS
18AkathisiaFAERS: 1SIDER
US FAERS
19AmnesiaFAERS: 1US FAERS
20AngerFAERS: 1US FAERS
21AngioedemaFAERS: 1SIDER
US FAERS
22AnxietyFAERS: 1SIDER
US FAERS
23BradycardiaFAERS: 1US FAERS
24Cardiac ArrestFAERS: 1US FAERS
25ChokingFAERS: 1US FAERS
26Completed SuicideFAERS: 1SIDER
US FAERS
27DeliriumFAERS: 1US FAERS
28DiplopiaFAERS: 1US FAERS
29Disease recurrenceFAERS: 1US FAERS
30Drug ineffectiveFAERS: 1US FAERS
31DysgeusiaFAERS: 1SIDER
US FAERS
32EpilepsyFAERS: 1US FAERS
33FatigueFAERS: 1SIDER
US FAERS
34FlatulenceFAERS: 1US FAERS
35GlossitisFAERS: 1US FAERS
36HeadacheFAERS: 1SIDER
US FAERS
37HomicideFAERS: 1US FAERS
38HypersensitivityFAERS: 1SIDER
US FAERS
39Inappropriate schedule of drug administrationFAERS: 1US FAERS
40IncontinenceFAERS: 1US FAERS
41Incorrect dose administeredFAERS: 1US FAERS
42Male sexual dysfunctionFAERS: 1US FAERS
43PainFAERS: 1US FAERS
44PneumoniaFAERS: 1US FAERS
45Respiratory FailureFAERS: 1US FAERS
46Sinus bradycardiaFAERS: 1SIDER
US FAERS
47SnoringFAERS: 1US FAERS
48SomnolenceFAERS: 1SIDER
US FAERS
49StridorFAERS: 1US FAERS
50Suicide attemptFAERS: 1US FAERS
51SwellingFAERS: 1SIDER
US FAERS
52TremorFAERS: 1SIDER
US FAERS
53VomitingFAERS: 1SIDER
US FAERS
54WheezingFAERS: 1SIDER
US FAERS
55Wrong technique in drug usage processFAERS: 1US FAERS
56Wrong technique in product usage processFAERS: 1US FAERS
57Abdominal discomfortSIDER
58AgranulocytosisSIDER
59Alanine Aminotransferase IncreasedSIDER
60Anaphylactic shockSIDER
61Anaphylactoid ReactionSIDER
62ArthralgiaSIDER
63AstheniaSIDER
64Basal Ganglia Diseases20520283CTD
65Blood cholesterol increasedSIDER
66Blood prolactin increasedSIDER
67Blood triglycerides increasedSIDER
68ConstipationSIDER
69DermatitisSIDER
70Diabetes MellitusSIDER
71DyspepsiaSIDER
72Idiosyncratic drug reactionSIDER
73Increased prolactin levelSIDER
74InflammationSIDER
75LeukopeniaSIDER
76MalaiseSIDER
77MalnutritionSIDER
78Muscle RigiditySIDER
79Musculoskeletal discomfortSIDER
80Neuroleptic Malignant SyndromeSIDER
81NeutropeniaSIDER
82PregnancySIDER
83Pulmonary EmbolismSIDER
84Restless Legs SyndromeSIDER
85RhabdomyolysisSIDER
86Schizophrenia20520283CTD
SIDER
87Sexual DysfunctionSIDER
88ShockSIDER
89Sinus TachycardiaSIDER
90StomatitisSIDER
91SuicideSIDER
92SyncopeSIDER
93TachycardiaSIDER
94Tardive DyskinesiaSIDER
95ThrombocytopeniaSIDER
96ToothacheSIDER
97Traumatic liver injurySIDER
98UlcerSIDER
99Upset stomachSIDER
100nervous system disorderSIDER
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