MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

(UQVKZNNCIHJZLS-UHFFFAOYSA-N)

Structure

SMILES: Cn1c(N)nc2c1cc(cn2)c1ccccc1
Type(s): Investigational
Molecular Formula:: C13H12N4
Molecular Weight:: 224.261
Log P:: 2.7987
Hydrogen Bond Acceptor:: 4
Hydrogen Bond Donor:: 1
TPSA:: 56.73
CAS Number(s):: 105650-23-5; 138370-35-1

Synonym(s)

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

PhIP

External Link(s)

MeSH	C049584
PubChem Compound	1530
ChEBI	76290
CHEMBL	CHEMBL1213271
DrugBank	DB08398
KEGG	cpd:C16038
Therapeutic Target Database	D00ZAJ
ZINC	1850101

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Aberrant Crypt Foci	View details 9111214 9163695 10357789 12351151 12636105 14507667 14656947 15059925 20660995	CTD
2	Adenocarcinoma	View details 8039140 11285198 11751431 12097258 14507667 15132766 15459021 21081470	CTD
3	Adenoma	View details 11285198 14507667 21544799 23466459	CTD
4	Carcinoma in Situ	12507937	CTD
5	Carcinoma	View details 8014110 8185828 9433479 10657900 11137312 11289141 12203372 12376462 12606953 14522882 14633621 14656947 15609129 15637090 17173897 21489049	CTD
6	Carcinosarcoma	15132766	CTD
7	Chromosome Breakage	20583320 28160022	CTD
8	Colonic Neoplasms	View details 7846077 8014110 8352890 8608549 8844820 9515794 10383901 10503899 11181456 12034317 12151357 12351152 12706856 12901791 14507667 14656947 15059925 15459021 15635146 17404573 17909072 18283038 18424890 18616682 19666988 20715105 20951759 21081470 22006426 22323126 23306951	CTD
9	Colorectal Neoplasms	21544799 23466459	CTD
10	Disease Progression	22307971	CTD
11	Inflammation	22581815	CTD
12	Intestinal Neoplasms	View details 9111214 9163695 9500188 11285198 11323404 11420398 11470761 11756241 14514656 14706516 16343741 16962818 18283038	CTD
13	Intestinal Polyps	8561861	CTD
14	Lymphoma	10755388 11285198 17909072	CTD
15	Malnutrition	11285198	CTD
16	Mammary Neoplasms, Experimental	View details 8185828 8597530 8603490 9433479 9849579 9879772 10657900 11137312 11165753 11289141 11751431 12097258 12203372 12376462 12507937 12606953 12706856 14522882 14633621 15132766 15215175 15528215 15609129 15637090 16316942	CTD
17	Microsatellite Instability	10657900	CTD
18	Neoplasm Invasiveness	20951759 22307971	CTD
19	Neoplasm Metastasis	22307971	CTD
20	Neoplasms, Experimental	29877212	CTD
21	Neoplasms	18056474	CTD
22	Pancreatic Diseases	9500188	CTD
23	Poisoning	23466459	CTD
24	Prostatic Neoplasms	View details 11238188 11470761 12351152 14656947 17909072 19223546 20951759 22564066 22581815 29877212	CTD
25	Salivary Gland Neoplasms	18283038	CTD
26	Sebaceous Gland Neoplasms	18283038	CTD
27	Skin Neoplasms	18283038	CTD
28	Stomach Neoplasms	23313794	CTD
29	leukemia	10755388	CTD

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