MetaADEDB 2.0 @ LMMD
Bepridil
(UIEATEWHFDRYRU-UHFFFAOYSA-N)
Structure
SMILES
CC(COCC(N1CCCC1)CN(c1ccccc1)Cc1ccccc1)C
Type(s)
Approved; Withdrawn
ATC code(s)
C08EA02
Molecular Formula:
C24H34N2O
Molecular Weight:
366.540
Log P:
4.7681
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
15.71
CAS Number(s):
64706-54-3
Synonym(s)
1.
Bepridil
2.
1978-CERM
3.
Bedapin
4.
Bepadin
5.
Bepridil Monohydrochloride
6.
Bepridil Monohydrochloride, Monohydrate
7.
Bepridil Monohydrochloride, alpha-Isomer
8.
Bepridil, (+)-Isomer
9.
Bepridil, (+-)-Isomer
10.
Bepridil, (-)-Isomer
11.
Bepridil, alpha-Isomer
12.
CERM-1978
13.
Cordium
14.
Unicordium
15.
Vascor
16.
1978 CERM
17.
1978CERM
18.
Bepridil Monohydrochloride, alpha Isomer
19.
Bepridil, alpha Isomer
20.
CERM 1978
21.
CERM1978
22.
Monohydrochloride, Bepridil
23.
Monohydrochloride, alpha-Isomer Bepridil
External Link(s)
MeSHD015764
PubChem Compound2351
BindingDB78577
50017667
ChEBI3061
CHEMBLCHEMBL1008
DrugBankDB01244
DrugCentral342
IUPHAR/BPS Guide to PHARMACOLOGY2337
KEGGcpd:C06847
dr:D07520
Therapeutic Target DatabaseD0Y4JJ
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood lactate dehydrogenase increasedFAERS: 2OFFSIDES
US FAERS
2Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
3Ventricular FibrillationFAERS: 22726785
12235963		CTD
US FAERS
4Lymphocyte count increasedFAERS: 1US FAERS
5Lymphocyte stimulation test positiveFAERS: 1OFFSIDES
US FAERS
6Neutrophil percentage increasedFAERS: 1US FAERS
7PneumonitisFAERS: 1US FAERS
8Abdominal PainSIDER
9Abdominal discomfortSIDER
10Acute myocardial infarctionSIDER
11AgraphiaOFFSIDES
12AkathisiaSIDER
13Angina Pectoris6985297CTD
SIDER
14AnorexiaSIDER
15AnxietySIDER
16ArthritisSIDER
17AstheniaSIDER
18Atrial Fibrillation16723784
17243631
19609043		CTD
19Atrial Flutter16723784CTD
20Atrial tachycardiaOFFSIDES
21Atrioventricular BlockOFFSIDES
22Blood GlucoseOFFSIDES
23Blood creatine phosphokinase MB increasedOFFSIDES
24Blood creatine phosphokinase increasedOFFSIDES
25Blood lactate dehydrogenase decreasedOFFSIDES
26Bradycardia6985297
16723784
22744888		CTD
OFFSIDES
SIDER
27Brain natriuretic peptide increasedOFFSIDES
28Cardiomegaly9863145CTD
29Cardiotoxicity26259608CTD
30Cholestasis1360065CTD
31ConstipationSIDER
32DermatitisSIDER
33DiarrheaOFFSIDES
34Disseminated Intravascular CoagulationOFFSIDES
35Distress gastrointestinalSIDER
36DistressSIDER
37Dizziness16723784CTD
SIDER
38DrowsinessSIDER
39DyspepsiaOFFSIDES
SIDER
40Emotional distressSIDER
41EnterocolitisOFFSIDES
42Erectile dysfunctionSIDER
43Fatigue16723784CTD
44Feeling ColdOFFSIDES
45FlatulenceSIDER
46Gastric ulcerOFFSIDES
47GastritisSIDER
48Gastrointestinal PainSIDER
49HeadacheSIDER
50HemiplegiaOFFSIDES
51Hyperemia3871297CTD
52InfluenzaSIDER
53Intestinal Pseudo-Obstruction6332516CTD
54Leukocytosis1360065CTD
55Long QT Syndrome

View details

1532469
2203243
10780196
12419934
16178046
16723784
17531251
18786527
24052561
25822712
 		CTD
56Musculoskeletal discomfortSIDER
57MyalgiaSIDER
58NauseaSIDER
59NervousnessSIDER
60Neutrophil count decreasedOFFSIDES
61PainSIDER
62PalpitationsSIDER
63Pericardial effusionOFFSIDES
64PharyngitisSIDER
65Puncture site infectionOFFSIDES
66RhinitisSIDER
67ShockSIDER
68Sinus TachycardiaSIDER
69Sinus bradycardiaOFFSIDES
SIDER
70Skin irritationSIDER
71Skin tightnessOFFSIDES
72SomnolenceSIDER
73Sudden deathOFFSIDES
SIDER
74SuperinfectionSIDER
75SweatingSIDER
76SyncopeSIDER
77Tachycardia, Ventricular

View details

1390333
6332516
12235963
17243631
 		CTD
78Tachycardia6985297CTD
79TensionSIDER
80TinnitusSIDER
81Torsades de Pointes

View details

1532469
8230644
10780196
12419934
16178046
16723784
18786527
19609043
 		CTD
82TremorSIDER
83Vasodilation procedureSIDER
84VasodilationSIDER
85Ventricular Dysfunction, Left3871297CTD
86Ventricular arrhythmiaSIDER
87VertigoSIDER
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