MetaADEDB 2.0 @ LMMD
dihydrocodeine
(RBOXVHNMENFORY-DNJOTXNNSA-N)
Structure
SMILES
COc1ccc2c3c1O[C@@H]1[C@@]43CCN([C@H](C2)[C@@H]4CC[C@@H]1O)C
Type(s)
Approved; Illicit
ATC code(s)
N02AA08; N02AA58; N02AJ01; N02AJ02
Molecular Formula:
C18H23NO3
Molecular Weight:
301.380
Log P:
1.6630
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
41.93
CAS Number(s):
125-28-0
Synonym(s)
1.
dihydrocodeine
2.
Contugesic
3.
DF 118
4.
DHC Continus
5.
DHC Mundipharma
6.
Dicodin
7.
Paracodin
8.
Paracodina
9.
Rikodeine
10.
Tiamon
11.
Tosidrin
12.
dihydrocodeine acetate, (5alpha,6alpha)-isomer
13.
dihydrocodeine bitartrate
14.
dihydrocodeine hydrochloride, (5alpha,6alpha)-isomer
15.
dihydrocodeine phosphate (1:1), (5alpha,6alpha)-isomer
16.
dihydrocodeine tartrate (1:1), (5alpha,6alpha)-(R-(R*,R*))-isomer
17.
dihydrocodeine tartrate (1:1), (5alpha,6beta)-(R-(R*,R*))-isomer
18.
dihydrocodeine, (5alpha,6alpha,14alpha)-isomer
19.
dihydrocodeine, (5alpha,6beta)-isomer
20.
dihydrocodeine, (5alpha,6beta,14alpha)-isomer
21.
dihydrocodeine, thiocyanate salt (5alpha,6alpha)-isomer
22.
paramol 118
External Link(s)
MeSHC014481
PubChem Compound5284543
ChEBI135276
CHEMBLCHEMBL1595
DrugBankDB01551
DrugCentral886
IUPHAR/BPS Guide to PHARMACOLOGY7594
KEGGdr:D01481
dr:D07831
Therapeutic Target DatabaseD0T6RC
ZINC4215736
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug DependenceFAERS: 3US FAERS
2Intentional product misuseFAERS: 3US FAERS
3MalaiseFAERS: 2US FAERS
4OverdoseFAERS: 2OFFSIDES
US FAERS
5DependenceFAERS: 1US FAERS
6DizzinessFAERS: 1
Canada Vigilance: 1		8471588CTD
SIDER
Canada Vigilance
US FAERS
7Incorrect product dosage form administeredFAERS: 1US FAERS
8PruritusFAERS: 1SIDER
US FAERS
9Abdominal Pain8471588CTD
OFFSIDES
SIDER
10Abdominal tendernessOFFSIDES
11Abnormal clotting factorOFFSIDES
12AbscessOFFSIDES
13Acute kidney injury2759067CTD
14Acute myocardial infarctionOFFSIDES
15AdenocarcinomaOFFSIDES
16AgeusiaOFFSIDES
17AlveolitisOFFSIDES
18AngioedemaSIDER
19Ankle FractureOFFSIDES
20AnorgasmiaOFFSIDES
21ApathyOFFSIDES
22AspergillomaOFFSIDES
23Asthenic conditionsSIDER
24Bacillus infectionOFFSIDES
25Basal cell carcinomaOFFSIDES
26Biliary ColicSIDER
27Bilirubin conjugated increasedOFFSIDES
28Blood alkaline phosphatase increasedOFFSIDES
29Blood amylase increasedOFFSIDES
30Blood blisterOFFSIDES
31Blood creatine phosphokinase increasedOFFSIDES
32Blood potassium decreasedOFFSIDES
33Blood potassium increasedOFFSIDES
34Blood triglycerides increasedOFFSIDES
35Breast cancer stage IIIOFFSIDES
36BronchiectasisOFFSIDES
37BronchopneumoniaOFFSIDES
38CalciphylaxisOFFSIDES
39Central line infectionOFFSIDES
40CholangiolitisOFFSIDES
41Cholestasis of pregnancyOFFSIDES
42Chronic Obstructive Airway DiseaseOFFSIDES
43ConfabulationOFFSIDES
44Constipation8967533
11240075		CTD
SIDER
45CyanosisOFFSIDES
46CystOFFSIDES
47DeafnessOFFSIDES
48Depressed moodOFFSIDES
49DermatitisSIDER
50Device breakageOFFSIDES
51DiarrheaOFFSIDES
52DiverticulumOFFSIDES
53DrowsinessOFFSIDES
54Drug Overdose17852162CTD
55Drug exposure during pregnancyOFFSIDES
56Drug toxicityOFFSIDES
57Ear and labyrinth disordersSIDER
58Eczema weepingOFFSIDES
59EczemaOFFSIDES
60Electromechanical dissociationOFFSIDES
61Enterococcal infectionOFFSIDES
62Epstein-Barr virus antibody positiveOFFSIDES
63Erythema MultiformeOFFSIDES
64Fatty LiverOFFSIDES
65Febrile NeutropeniaOFFSIDES
66Feeling abnormalSIDER
67Gastric ulcerOFFSIDES
68Gastrointestinal PainSIDER
69Gastrointestinal hypomotilityOFFSIDES
70Global AmnesiaOFFSIDES
71GlobulinuriaOFFSIDES
72GranulomaOFFSIDES
73Hallucinations719349
8882268		CTD
74Headache8471588
8967533		CTD
SIDER
75Hepatic congestionOFFSIDES
76Hepatic necrosisOFFSIDES
77Hyperalgesia4020808CTD
78HypotensionSIDER
79Increased upper airway secretionOFFSIDES
80Intestinal infarctionOFFSIDES
81Joint abscessOFFSIDES
82Jugular vein distensionOFFSIDES
83Live BirthOFFSIDES
84LymphomaOFFSIDES
85Malignant neoplasm progressionOFFSIDES
86Mesenteric vascular insufficiencyOFFSIDES
87Metabolic acidosisOFFSIDES
88Mood swingsSIDER
89Morbid thoughtsOFFSIDES
90Multiple SclerosisOFFSIDES
91Multiple drug overdoseOFFSIDES
92Musculoskeletal PainOFFSIDES
93NauseaCanada Vigilance: 14930206
8471588
8967533		CTD
SIDER
Canada Vigilance
94Ocular icterusOFFSIDES
95Oropharyngeal blisteringOFFSIDES
96OsteomyelitisOFFSIDES
97Pain, Postoperative6123928
8471588
8967533		CTD
98Pain4930206
11240075		CTD
99PancreatitisOFFSIDES
100Pericardial effusionOFFSIDES
101PeritonitisOFFSIDES
102Pharyngolaryngeal PainOFFSIDES
103PneumoperitoneumOFFSIDES
104PneumothoraxOFFSIDES
105Prostate cancer stage 0OFFSIDES
106Psychiatric symptomOFFSIDES
107Pulmonary function test decreasedSIDER
108Respiratory DepressionSIDER
109Restrictive pulmonary diseaseOFFSIDES
110RhabdomyolysisOFFSIDES
111Sense of oppressionOFFSIDES
112Sick Sinus Syndrome17441449CTD
113Skeletal injuryOFFSIDES
114Skin necrosisOFFSIDES
115Skin reactionCanada Vigilance: 1Canada Vigilance
116SomnolenceSIDER
117Sputum culture positiveOFFSIDES
118StridorOFFSIDES
119Stupor2759067CTD
120Sudden deathOFFSIDES
121Synovial CystOFFSIDES
122Therapy non-responderOFFSIDES
123TracheobronchitisOFFSIDES
124UlcerOFFSIDES
125Urinary RetentionSIDER
126UrticariaSIDER
127VertigoSIDER
128VomitingCanada Vigilance: 24930206
8471588
8967533		CTD
SIDER
Canada Vigilance
129nervous system disorderSIDER
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