rimexolone
(QTTRZHGPGKRAFB-OOKHYKNYSA-N)
Structure
- SMILES
- CCC(=O)[C@@]1(C)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C
- Type(s)
- Approved
- ATC code(s)
- H02AB12; S01BA13
- Molecular Formula:
- C24H34O3
- Molecular Weight:
- 370.525
- Log P:
- 4.4965
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 1
- TPSA:
- 54.37
- CAS Number(s):
- 49697-38-3
Synonym(s)
1.
rimexolone
2.
11 beta-hydroxy-16 alpha,17 alpha,21-trimethylpregna-1,4-diene-3,20-dione
3.
Org 6216
4.
Org-6216
5.
Rimexel
6.
Vexol
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Blindness | FAERS: 3 | US FAERS | |
| 2 | Astigmatism | FAERS: 2 | US FAERS | |
| 3 | Ocular Hypertension | FAERS: 2 | 8694727 10088814 14662591 | CTD US FAERS |
| 4 | Suture rupture | FAERS: 2 | US FAERS | |
| 5 | Corneal abscess | FAERS: 1 | US FAERS | |
| 6 | Eye Infection | FAERS: 1 | SIDER US FAERS | |
| 7 | Eyelid margin crusting | FAERS: 1 | US FAERS | |
| 8 | Fatigue | FAERS: 1 | US FAERS | |
| 9 | Growth retardation | FAERS: 1 | US FAERS | |
| 10 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 11 | Muscle Fatigue | FAERS: 1 | US FAERS | |
| 12 | Night sweats | FAERS: 1 | US FAERS | |
| 13 | Orbital infection | FAERS: 1 | US FAERS | |
| 14 | Pharyngitis | FAERS: 1 | SIDER US FAERS | |
| 15 | Pneumonia | FAERS: 1 | US FAERS | |
| 16 | Rhinitis | FAERS: 1 | SIDER US FAERS | |
| 17 | nervous system disorder | FAERS: 1 | US FAERS | |
| 18 | Corneal erosion | SIDER | ||
| 19 | Corneal thinning | SIDER | ||
| 20 | Discomfort | SIDER | ||
| 21 | Dysgeusia | SIDER | ||
| 22 | Eye irritation | Canada Vigilance: 1 | Canada Vigilance | |
| 23 | Eye pain | SIDER | ||
| 24 | Headache | SIDER | ||
| 25 | Hypotension | SIDER | ||
| 26 | Keratitis | SIDER | ||
| 27 | Lacrimation | SIDER | ||
| 28 | Nerve injury | SIDER | ||
| 29 | Photophobia | SIDER | ||
| 30 | Posterior subcapsular cataract | SIDER | ||
| 31 | Pruritus | SIDER | ||
| 32 | Scab | SIDER | ||
| 33 | Vital dye staining cornea present | SIDER |
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