perampanel
(PRMWGUBFXWROHD-UHFFFAOYSA-N)
Structure
- SMILES
- N#Cc1ccccc1c1cc(cn(c1=O)c1ccccc1)c1ccccn1
- Type(s)
- Approved
- ATC code(s)
- N03AX22
- Molecular Formula:
- C23H15N3O
- Molecular Weight:
- 349.385
- Log P:
- 4.4382
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 0
- TPSA:
- 58.68
- CAS Number(s):
- 380917-97-5
Synonym(s)
1.
perampanel
2.
3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Dizziness | FAERS: 28 | SIDER US FAERS | |
| 2 | Somnolence | FAERS: 14 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 3 | Agitation | FAERS: 13 | US FAERS | |
| 4 | Drug ineffective | FAERS: 13 | US FAERS | |
| 5 | Suicide attempt | FAERS: 12 | US FAERS | |
| 6 | Anger | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 7 | Fatigue | FAERS: 8 | SIDER US FAERS | |
| 8 | Ataxia | FAERS: 7 | SIDER US FAERS | |
| 9 | Headache | FAERS: 7 | SIDER US FAERS | |
| 10 | Overdose | FAERS: 6 | US FAERS | |
| 11 | Physical assault | FAERS: 6 | US FAERS | |
| 12 | Mood swings | FAERS: 5 | SIDER US FAERS | |
| 13 | Paranoia | FAERS: 5 | US FAERS | |
| 14 | Product use issue | FAERS: 5 | US FAERS | |
| 15 | Anxiety | FAERS: 4 | SIDER US FAERS | |
| 16 | Dysarthria | FAERS: 4 | SIDER US FAERS | |
| 17 | Vertigo | FAERS: 4 | SIDER US FAERS | |
| 18 | Constipation | FAERS: 3 | SIDER US FAERS | |
| 19 | Disorientation | FAERS: 3 | US FAERS | |
| 20 | Drug administered to patient of inappropriate age | FAERS: 3 | US FAERS | |
| 21 | Epilepsy | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 22 | Fracture | FAERS: 3 | US FAERS | |
| 23 | Gait inability | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 24 | Nausea | FAERS: 3 | SIDER US FAERS | |
| 25 | Personality Change | FAERS: 3 | US FAERS | |
| 26 | Psychiatric symptom | FAERS: 3 | US FAERS | |
| 27 | Status Epilepticus | FAERS: 3 | US FAERS | |
| 28 | Vomiting | FAERS: 3 | SIDER US FAERS | |
| 29 | Accidental overdose | FAERS: 2 | US FAERS | |
| 30 | Acute kidney injury | FAERS: 2 | US FAERS | |
| 31 | Aphasia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Back Pain | FAERS: 2 | SIDER US FAERS | |
| 33 | Completed Suicide | FAERS: 2 | US FAERS | |
| 34 | Drug withdrawal convulsions | FAERS: 2 | US FAERS | |
| 35 | Erythema | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 36 | Feeling abnormal | FAERS: 2 | SIDER US FAERS | |
| 37 | Memory impairment | FAERS: 2 | SIDER US FAERS | |
| 38 | Musculoskeletal Pain | FAERS: 2 | SIDER US FAERS | |
| 39 | Myalgia | FAERS: 2 | SIDER US FAERS | |
| 40 | Myocardial Infarction | FAERS: 2 | US FAERS | |
| 41 | Pneumonia | FAERS: 2 | US FAERS | |
| 42 | Prescription drug used without a prescription | FAERS: 2 | US FAERS | |
| 43 | Restlessness | FAERS: 2 | US FAERS | |
| 44 | Rhabdomyolysis | FAERS: 2 | US FAERS | |
| 45 | Skin Ulcer | FAERS: 2 | US FAERS | |
| 46 | Somnambulism | FAERS: 2 | US FAERS | |
| 47 | Therapy change | FAERS: 2 | US FAERS | |
| 48 | Tremor | FAERS: 2 | US FAERS | |
| 49 | Violence-related symptom | FAERS: 2 | US FAERS | |
| 50 | Vulvovaginal discomfort | FAERS: 2 | US FAERS | |
| 51 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 52 | Accidental exposure to product by child | FAERS: 1 | US FAERS | |
| 53 | Acne | FAERS: 1 | US FAERS | |
| 54 | Acute psychosis | FAERS: 1 | US FAERS | |
| 55 | Ankle Fracture | FAERS: 1 | US FAERS | |
| 56 | Arthralgia | FAERS: 1 | SIDER US FAERS | |
| 57 | Asphyxia | FAERS: 1 | US FAERS | |
| 58 | Asthenia | FAERS: 1 | SIDER US FAERS | |
| 59 | Autoimmune hepatitis | FAERS: 1 | US FAERS | |
| 60 | Blindness | FAERS: 1 | US FAERS | |
| 61 | Blood glucose increased | FAERS: 1 | US FAERS | |
| 62 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 63 | Bradykinesia | FAERS: 1 | US FAERS | |
| 64 | Bradyphrenia | FAERS: 1 | US FAERS | |
| 65 | Congenital diaphragmatic hernia | FAERS: 1 | US FAERS | |
| 66 | Crying | FAERS: 1 | US FAERS | |
| 67 | Cyanosis | FAERS: 1 | US FAERS | |
| 68 | Cystic Fibrosis | FAERS: 1 | US FAERS | |
| 69 | Deafness | FAERS: 1 | US FAERS | |
| 70 | Delirium | FAERS: 1 | US FAERS | |
| 71 | Delusional perception | FAERS: 1 | US FAERS | |
| 72 | Drowning | FAERS: 1 | US FAERS | |
| 73 | Drug Dependence | FAERS: 1 | US FAERS | |
| 74 | Drug administration error | FAERS: 1 | US FAERS | |
| 75 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 76 | Electroencephalogram abnormal | FAERS: 1 | US FAERS | |
| 77 | Encephalitis | FAERS: 1 | US FAERS | |
| 78 | Erection increased | FAERS: 1 | US FAERS | |
| 79 | Euphoric mood | FAERS: 1 | SIDER US FAERS | |
| 80 | Foaming at mouth | FAERS: 1 | US FAERS | |
| 81 | Head Banging | FAERS: 1 | US FAERS | |
| 82 | Hostility | FAERS: 1 | US FAERS | |
| 83 | Hyperkinesia | FAERS: 1 | US FAERS | |
| 84 | Influenza | FAERS: 1 | US FAERS | |
| 85 | Intentional self-injury | FAERS: 1 | US FAERS | |
| 86 | Leukocytosis | FAERS: 1 | US FAERS | |
| 87 | Lip swelling | FAERS: 1 | US FAERS | |
| 88 | Malaise | FAERS: 1 | US FAERS | |
| 89 | Metamorphopsia | FAERS: 1 | US FAERS | |
| 90 | Muscle Spasticity | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 91 | Nervousness | FAERS: 1 | US FAERS | |
| 92 | Ophthalmoplegic Migraine | FAERS: 1 | US FAERS | |
| 93 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 94 | Polydipsia | FAERS: 1 | US FAERS | |
| 95 | Postictal psychosis | FAERS: 1 | US FAERS | |
| 96 | Pruritus | FAERS: 1 | US FAERS | |
| 97 | Psychotic symptom | FAERS: 1 | US FAERS | |
| 98 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 99 | Retching | FAERS: 1 | US FAERS | |
| 100 | Secretion discharge | FAERS: 1 | US FAERS | |
| 101 | Staring | FAERS: 1 | US FAERS | |
| 102 | Sudden death | FAERS: 1 | US FAERS | |
| 103 | Swelling | FAERS: 1 | US FAERS | |
| 104 | Therapy cessation | FAERS: 1 | US FAERS | |
| 105 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 106 | Tongue movement disturbance | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 107 | Transaminases increased | FAERS: 1 | US FAERS | |
| 108 | Urinary Retention | FAERS: 1 | US FAERS | |
| 109 | Visual Impairment | FAERS: 1 | US FAERS | |
| 110 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 111 | Cortical Dysplasia | Canada Vigilance: 1 | Canada Vigilance | |
| 112 | Diplopia | SIDER | ||
| 113 | Ear and labyrinth disorders | SIDER | ||
| 114 | Hypersomnia | SIDER | ||
| 115 | Infection | SIDER | ||
| 116 | Infestation | SIDER | ||
| 117 | Laceration | SIDER | ||
| 118 | Limb injury | SIDER | ||
| 119 | Malnutrition | SIDER | ||
| 120 | Musculoskeletal discomfort | SIDER | ||
| 121 | Oropharyngeal pain | SIDER | ||
| 122 | Skin laceration | SIDER | ||
| 123 | nervous system disorder | SIDER |
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