Maprotiline
(NZDMFGKECODQRY-UHFFFAOYSA-N)
Structure
- SMILES
- CNCCCC12CCC(c3c1cccc3)c1c2cccc1.Cl
- Molecular Formula:
- C20H24ClN
- Molecular Weight:
- 313.864
- Log P:
- 5.4043
- Hydrogen Bond Acceptor:
- 1
- Hydrogen Bond Donor:
- 2
- TPSA:
- 12.03
- CAS Number(s):
- 10347-81-6
Synonym(s)
1.
Maprotiline
2.
Ba-34,276
3.
Deprilept
4.
Dibencycladine
5.
Ludiomil
6.
Maprolu
7.
Maprotilin
8.
Maprotilin Holsten
9.
Maprotilin-TEVA
10.
Maprotilin-neuraxpharm
11.
Maprotilin-ratiopharm
12.
Maprotiline Hydrochloride
13.
Maprotiline Mesylate
14.
Mirpan
15.
N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine
16.
Novo-Maprotiline
17.
Psymion
18.
maprotilin von ct
19.
Ba34,276
20.
Hydrochloride, Maprotiline
21.
Maprotilin TEVA
22.
Maprotilin neuraxpharm
23.
Maprotilin ratiopharm
24.
Mesylate, Maprotiline
25.
Novo Maprotiline
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hypotension | FAERS: 5 | US FAERS | |
| 2 | Neuroleptic Malignant Syndrome | FAERS: 5 | US FAERS | |
| 3 | Akinesia | FAERS: 3 | US FAERS | |
| 4 | Dysphonia | FAERS: 3 | US FAERS | |
| 5 | Ileus | FAERS: 3 | US FAERS | |
| 6 | Overdose | FAERS: 3 | US FAERS | |
| 7 | Pneumonia | FAERS: 3 | US FAERS | |
| 8 | Altered state of consciousness | FAERS: 2 | US FAERS | |
| 9 | Aphasia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Blood creatine phosphokinase increased | FAERS: 2 | US FAERS | |
| 11 | Catatonia | FAERS: 2 | US FAERS | |
| 12 | Drug exposure during pregnancy | FAERS: 2 | US FAERS | |
| 13 | Dysuria | FAERS: 2 | US FAERS | |
| 14 | Mechanical ventilation | FAERS: 2 | US FAERS | |
| 15 | Oral discharge | FAERS: 2 | US FAERS | |
| 16 | Pleurisy | FAERS: 2 | US FAERS | |
| 17 | Somnolence | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 18 | Staring | FAERS: 2 | US FAERS | |
| 19 | Suicide attempt | FAERS: 2 | US FAERS | |
| 20 | Syncope | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 21 | Temperature intolerance | FAERS: 2 | US FAERS | |
| 22 | Urticaria | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 23 | Abasia | FAERS: 1 | US FAERS | |
| 24 | Accidental exposure | FAERS: 1 | US FAERS | |
| 25 | Asthenia | FAERS: 1 | US FAERS | |
| 26 | Atrioventricular Block | FAERS: 1 | US FAERS | |
| 27 | Blood glucose increased | FAERS: 1 | US FAERS | |
| 28 | Blood lactate dehydrogenase increased | FAERS: 1 | US FAERS | |
| 29 | Blood thyroid stimulating hormone decreased | FAERS: 1 | US FAERS | |
| 30 | Bronchoalveolar lavage abnormal | FAERS: 1 | US FAERS | |
| 31 | Cell marker increased | FAERS: 1 | US FAERS | |
| 32 | Cerebral Infarction | FAERS: 1 | US FAERS | |
| 33 | Cerebral atrophy | FAERS: 1 | US FAERS | |
| 34 | Chest discomfort | FAERS: 1 | US FAERS | |
| 35 | Chorea | FAERS: 1 | US FAERS | |
| 36 | Completed Suicide | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 37 | Drug level increased | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 38 | Drug toxicity | FAERS: 1 | US FAERS | |
| 39 | Dyspepsia | FAERS: 1 | US FAERS | |
| 40 | Electroconvulsive Therapy | FAERS: 1 | US FAERS | |
| 41 | Eosinophilic Pneumonia | FAERS: 1 | US FAERS | |
| 42 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 43 | Gastric Lavage | FAERS: 1 | US FAERS | |
| 44 | Hyperthyroidism | FAERS: 1 | US FAERS | |
| 45 | Intentional misuse | FAERS: 1 | US FAERS | |
| 46 | Malaise | FAERS: 1 | US FAERS | |
| 47 | Monoplegia | FAERS: 1 | US FAERS | |
| 48 | Myalgia | FAERS: 1 | US FAERS | |
| 49 | Mydriasis | FAERS: 1 | US FAERS | |
| 50 | Neck Pain | FAERS: 1 | US FAERS | |
| 51 | Negativism | FAERS: 1 | US FAERS | |
| 52 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 53 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 54 | Pharyngitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 55 | Pneumonitis | FAERS: 1 | US FAERS | |
| 56 | Renal cyst | FAERS: 1 | US FAERS | |
| 57 | Renal pain | FAERS: 1 | US FAERS | |
| 58 | Therapeutic product ineffective | FAERS: 1 | US FAERS | |
| 59 | Thirst | FAERS: 1 | US FAERS | |
| 60 | Throat irritation | FAERS: 1 | US FAERS | |
| 61 | Thrombosis | FAERS: 1 | US FAERS | |
| 62 | Toxic Epidermal Necrolysis | FAERS: 1 | US FAERS | |
| 63 | Urinary Retention | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 64 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 65 | Ventricular Fibrillation | FAERS: 1 | US FAERS | |
| 66 | Ventricular arrhythmia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 67 | Vomiting | FAERS: 1 | US FAERS | |
| 68 | Weight decreased | FAERS: 1 | US FAERS | |
| 69 | Abdominal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 70 | Akathisia | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Anaphylactoid Reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 72 | Angioedema | Canada Vigilance: 1 | Canada Vigilance | |
| 73 | Anxiety | Canada Vigilance: 1 | Canada Vigilance | |
| 74 | Arthropathy | Canada Vigilance: 1 | Canada Vigilance | |
| 75 | Cholestasis | Canada Vigilance: 1 | Canada Vigilance | |
| 76 | Conjunctivitis | Canada Vigilance: 1 | Canada Vigilance | |
| 77 | Constipation | Canada Vigilance: 1 | Canada Vigilance | |
| 78 | Disorientation | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Dizziness | Canada Vigilance: 3 | Canada Vigilance | |
| 80 | Drug ineffective | Canada Vigilance: 1 | Canada Vigilance | |
| 81 | Electroencephalogram abnormal | Canada Vigilance: 2 | Canada Vigilance | |
| 82 | Emotional distress | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Glycosuria | Canada Vigilance: 1 | Canada Vigilance | |
| 84 | Headache | Canada Vigilance: 1 | Canada Vigilance | |
| 85 | Hyperkinesia | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Laryngospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 87 | Leukopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Muscle Spasticity | Canada Vigilance: 1 | Canada Vigilance | |
| 89 | Myocardial Infarction | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Nausea | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 92 | Pancytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 93 | Pruritus | Canada Vigilance: 6 | Canada Vigilance | |
| 94 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 95 | Stevens-Johnson Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 96 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 97 | Systemic lupus erythematosus rash | Canada Vigilance: 1 | Canada Vigilance | |
| 98 | Tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 99 | Tinnitus | Canada Vigilance: 2 | Canada Vigilance | |
| 100 | Tremor | Canada Vigilance: 5 | Canada Vigilance | |
| 101 | Urinary Incontinence | Canada Vigilance: 2 | Canada Vigilance | |
| 102 | Vasculitis | Canada Vigilance: 1 | Canada Vigilance | |
| 103 | Vertigo | Canada Vigilance: 1 | Canada Vigilance | |
| 104 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120238
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.