MetaADEDB 2.0 @ LMMD
Pemoline
(NRNCYVBFPDDJNE-UHFFFAOYSA-N)
Structure
SMILES
O=C1N=C(OC1c1ccccc1)N
Type(s)
Approved; Illicit; Investigational; Withdrawn
ATC code(s)
N06BA05
Molecular Formula:
C9H8N2O2
Molecular Weight:
176.172
Log P:
0.7351
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
64.68
CAS Number(s):
2152-34-3; 101053-01-4
Synonym(s)
1.
Pemoline
2.
Phenoxazole
3.
Phenylisohydantoin
4.
Cylert
5.
PemADD
6.
Pemoline Compounds
7.
Pemoline Magnesium
8.
Tradon
9.
Compounds, Pemoline
10.
Magnesium, Pemoline
External Link(s)
MeSHD010389
PubChem Compound4723
137628477
BindingDB50248019
ChEBI7953
CHEMBLCHEMBL1177
DrugBankDB01230
DrugCentral2075
KEGGcpd:C07899
dr:D00744
Therapeutic Target DatabaseD0D5GG
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 3US FAERS
2Pharmaceutical product complaintFAERS: 3US FAERS
3FatigueFAERS: 2
Canada Vigilance: 1		9565425CTD
Canada Vigilance
US FAERS
4Feeling abnormalFAERS: 2US FAERS
5Feeling jitteryFAERS: 2US FAERS
6AgitationFAERS: 1US FAERS
7ApathyFAERS: 1US FAERS
8AphagiaFAERS: 1US FAERS
9AscitesFAERS: 1US FAERS
10Carbon Monoxide PoisoningFAERS: 1US FAERS
11DizzinessFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
12HeadacheFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
13Hepatic EncephalopathyFAERS: 19565425CTD
US FAERS
14Hepatic necrosisFAERS: 1US FAERS
15HepatomegalyFAERS: 19565425CTD
US FAERS
16InflammationFAERS: 1US FAERS
17OverdoseFAERS: 1US FAERS
18PainFAERS: 1US FAERS
19Poor quality drug administeredFAERS: 1US FAERS
20Rebound effectFAERS: 1US FAERS
21Suicide attemptFAERS: 1US FAERS
22Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
23jaundiceFAERS: 1
Canada Vigilance: 1		9565425
12132793		CTD
Canada Vigilance
US FAERS
24Abdominal PainCanada Vigilance: 16630594CTD
Canada Vigilance
25Anorexia6796134CTD
26Arterial thrombosisCanada Vigilance: 1Canada Vigilance
27AstheniaCanada Vigilance: 1Canada Vigilance
28Athetosis2723130
3367787
9022662		CTD
29Attention Deficit and Disruptive Behavior Disorders6630594
9100429		CTD
30Autoimmune Diseases9565425CTD
31Bipolar Disorder6796134CTD
32Cerebral InfarctionCanada Vigilance: 1Canada Vigilance
33Chemical and Drug Induced Liver Injury

View details

7781270
9100429
9417161
9565425
18217792
25900201
 		CTD
34Chorea

View details

2723130
3367787
6830189
7193830
9022662
 		CTD
35Constipation6630594CTD
36Conversion disorderCanada Vigilance: 1Canada Vigilance
37CryingCanada Vigilance: 1Canada Vigilance
38Depressive disorder6630594CTD
39Drug Overdose9022662CTD
40Dyskinesia, Drug-Induced10085879CTD
41Fatty Liver9565425CTD
42Feeding and Eating Disorders6630594CTD
43Fibrosis9565425CTD
44Hypotension11049895CTD
45LeukopeniaCanada Vigilance: 2Canada Vigilance
46Liver Failure, Acute

View details

7781270
9565425
12132793
18217792
 		CTD
47Liver Failure9562136CTD
48Mental disorders20974187CTD
49Multiple Sclerosis8855756CTD
50NauseaCanada Vigilance: 1Canada Vigilance
51Necrosis9565425CTD
52Personality Disorders15582667CTD
53Psychoses, Substance-Induced4021028CTD
54Rhabdomyolysis3367787CTD
55Sleep Initiation and Maintenance Disorders6630594
6796134		CTD
56Stuttering2040720CTD
57Substance Withdrawal Syndrome3971647CTD
58Syncope6630594CTD
59Visual ImpairmentCanada Vigilance: 1Canada Vigilance
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