MetaADEDB 2.0 @ LMMD
ebastine
(MJJALKDDGIKVBE-UHFFFAOYSA-N)
Structure
SMILES
O=C(c1ccc(cc1)C(C)(C)C)CCCN1CCC(CC1)OC(c1ccccc1)c1ccccc1
Type(s)
Approved; Investigational
ATC code(s)
R06AX22
Molecular Formula:
C32H39NO2
Molecular Weight:
469.658
Log P:
7.1555
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
29.54
CAS Number(s):
90729-43-4
Synonym(s)
1.
ebastine
2.
4-diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine
3.
Bactil
4.
Busidril
5.
Ebastel
6.
Evastel
7.
Kestin
8.
Kestine
9.
LAS W-090
External Link(s)
MeSHC058249
PubChem Compound3191
BindingDB22873
ChEBI31528
CHEMBLCHEMBL305660
DrugBankDB11742
DrugCentral977
KEGGdr:D01478
ZINC3781952
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1EpistaxisFAERS: 1US FAERS
2Abdominal tendernessOFFSIDES
3Abscess sweat glandOFFSIDES
4Acute bronchitisOFFSIDES
5Alcoholic IntoxicationOFFSIDES
6Anoxic EncephalopathyOFFSIDES
7AutomatismOFFSIDES
8Basophil percentage increasedOFFSIDES
9Beta 2 microglobulin increasedOFFSIDES
10Blood amylase increasedOFFSIDES
11Blood creatine phosphokinase MB increasedOFFSIDES
12Blood creatine phosphokinase increasedOFFSIDES
13Blood glucose decreasedOFFSIDES
14Blood immunoglobulin EOFFSIDES
15CatatoniaOFFSIDES
16Cerebral ventricle dilatationOFFSIDES
17Complications of transplant surgeryOFFSIDES
18Concomitant disease aggravatedOFFSIDES
19Depressed Level of ConsciousnessOFFSIDES
20DiverticulitisOFFSIDES
21DrowsinessOFFSIDES
22Drug toxicityOFFSIDES
23Duodenal ulcer perforationOFFSIDES
24DyslaliaOFFSIDES
25EctropionOFFSIDES
26EczemaOFFSIDES
27Emphysematous bullaOFFSIDES
28EnterocolitisOFFSIDES
29EpilepsyOFFSIDES
30ErythemaOFFSIDES
31Food aversionOFFSIDES
32Gamma-glutamyltransferase abnormalOFFSIDES
33Gastric Antral Vascular EctasiaOFFSIDES
34Granulocyte count decreasedOFFSIDES
35Hepatic vein occlusionOFFSIDES
36Herpes Zoster OticusOFFSIDES
37HypertransaminasaemiaOFFSIDES
38HypoxiaOFFSIDES
39Idiopathic urticariaOFFSIDES
40Intentional drug misuseOFFSIDES
41Large intestine perforationOFFSIDES
42Liver transplant rejectionOFFSIDES
43Long QT Syndrome20455340CTD
44Lymphocyte count decreasedOFFSIDES
45Lymphocyte percentage decreasedOFFSIDES
46Lysosomal Storage Diseases28551711CTD
47MacrocytosisOFFSIDES
48MeningoceleOFFSIDES
49Monocyte percentage decreasedOFFSIDES
50Monocyte percentage increasedOFFSIDES
51Mycosis FungoidesOFFSIDES
52Oculomucocutaneous syndromeOFFSIDES
53PO2 decreasedOFFSIDES
54Pancreatic enzymes increasedOFFSIDES
55ParakeratosisOFFSIDES
56Pericardial effusionOFFSIDES
57PleurisyOFFSIDES
58PneumothoraxOFFSIDES
59PoriomaniaOFFSIDES
60Pulmonary InfarctionOFFSIDES
61RhabdomyolysisOFFSIDES
62Rhinitis10444230CTD
63Small intestine carcinomaOFFSIDES
64Sudden deathOFFSIDES
65SynovitisOFFSIDES
66TinnitusOFFSIDES
67Urticaria10444230CTD
68VIIth nerve paralysisOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.