Fluphenazine
(MBHNWCYEGXQEIT-UHFFFAOYSA-N)
Structure
- SMILES
- OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F.Cl.Cl
- Molecular Formula:
- C22H28Cl2F3N3OS
- Molecular Weight:
- 510.443
- Log P:
- 5.8529
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 3
- TPSA:
- 55.25
- CAS Number(s):
- 146-56-5
Synonym(s)
1.
Fluphenazine
2.
Flufenazin
3.
Fluphenazine Hydrochloride
4.
Lyogen
5.
Prolixin
6.
Hydrochloride, Fluphenazine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Tardive Dyskinesia | FAERS: 6 | US FAERS | |
| 2 | Constipation | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Dizziness | FAERS: 3 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 4 | Fatigue | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Myalgia | FAERS: 3 | US FAERS | |
| 6 | Neuroleptic Malignant Syndrome | FAERS: 3 | US FAERS | |
| 7 | Pharmaceutical product complaint | FAERS: 3 | US FAERS | |
| 8 | Headache | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Joint stiffness | FAERS: 2 | US FAERS | |
| 10 | Lethargy | FAERS: 2 | US FAERS | |
| 11 | Malaise | FAERS: 2 | US FAERS | |
| 12 | Nausea | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Pneumonia | FAERS: 2 | US FAERS | |
| 14 | Somnolence | FAERS: 2 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 15 | Tooth Loss | FAERS: 2 | US FAERS | |
| 16 | Vomiting | FAERS: 2 | US FAERS | |
| 17 | Abulia | FAERS: 1 | US FAERS | |
| 18 | Accidental exposure | FAERS: 1 | US FAERS | |
| 19 | Akinesia | FAERS: 1 | US FAERS | |
| 20 | Alopecia | FAERS: 1 | US FAERS | |
| 21 | Arthralgia | FAERS: 1 | US FAERS | |
| 22 | Arthritis | FAERS: 1 | US FAERS | |
| 23 | Asthenia | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 24 | Bipolar Disorder | FAERS: 1 | US FAERS | |
| 25 | Blepharospasm | FAERS: 1 | US FAERS | |
| 26 | Blood chloride decreased | FAERS: 1 | US FAERS | |
| 27 | Blood potassium decreased | FAERS: 1 | US FAERS | |
| 28 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 29 | Burning sensation | FAERS: 1 | US FAERS | |
| 30 | Coronary Artery Disease | FAERS: 1 | US FAERS | |
| 31 | Dehydration | FAERS: 1 | US FAERS | |
| 32 | Dental caries | FAERS: 1 | US FAERS | |
| 33 | Disorientation | FAERS: 1 | US FAERS | |
| 34 | Drooling | FAERS: 1 | US FAERS | |
| 35 | Drug Dependence | FAERS: 1 | US FAERS | |
| 36 | Drug abuse | FAERS: 1 | US FAERS | |
| 37 | Drug ineffective | FAERS: 1 | US FAERS | |
| 38 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 39 | Dyspareunia | FAERS: 1 | US FAERS | |
| 40 | Dystonia | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 41 | Eye pain | FAERS: 1 | US FAERS | |
| 42 | Feeling Cold | FAERS: 1 | US FAERS | |
| 43 | Hypersensitivity | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 44 | Injection site erythema | FAERS: 1 | US FAERS | |
| 45 | Intentional misuse | FAERS: 1 | US FAERS | |
| 46 | Joint swelling | FAERS: 1 | US FAERS | |
| 47 | Macular degeneration | FAERS: 1 | US FAERS | |
| 48 | Medication Error | FAERS: 1 | US FAERS | |
| 49 | Memory impairment | FAERS: 1 | US FAERS | |
| 50 | Mood swings | FAERS: 1 | US FAERS | |
| 51 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 52 | Myocardial Infarction | FAERS: 1 | US FAERS | |
| 53 | Nervousness | FAERS: 1 | US FAERS | |
| 54 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 55 | Overdose | FAERS: 1 | US FAERS | |
| 56 | Pain | FAERS: 1 | US FAERS | |
| 57 | Palpitations | FAERS: 1 | US FAERS | |
| 58 | Rhabdomyolysis | FAERS: 1 | US FAERS | |
| 59 | Sudden death | FAERS: 1 | US FAERS | |
| 60 | Tachycardia | FAERS: 1 | US FAERS | |
| 61 | Toothache | FAERS: 1 | US FAERS | |
| 62 | Tremor | FAERS: 1 Canada Vigilance: 14 | Canada Vigilance US FAERS | |
| 63 | Unevaluable event | FAERS: 1 | US FAERS | |
| 64 | Visual Impairment | FAERS: 1 | US FAERS | |
| 65 | Weight decreased | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 66 | Agitation | Canada Vigilance: 2 | Canada Vigilance | |
| 67 | Akathisia | Canada Vigilance: 6 | Canada Vigilance | |
| 68 | Apathy | Canada Vigilance: 1 | Canada Vigilance | |
| 69 | Depressed Level of Consciousness | Canada Vigilance: 1 | Canada Vigilance | |
| 70 | Dysphonia | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Epilepsy | Canada Vigilance: 1 | Canada Vigilance | |
| 72 | Flushing | Canada Vigilance: 1 | Canada Vigilance | |
| 73 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 74 | Leukopenia | Canada Vigilance: 2 | Canada Vigilance | |
| 75 | Muscle Rigidity | Canada Vigilance: 4 | Canada Vigilance | |
| 76 | Muscle Spasticity | Canada Vigilance: 1 | Canada Vigilance | |
| 77 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 78 | Nystagmus | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Oculogyric crisis | Canada Vigilance: 2 | Canada Vigilance | |
| 80 | Opisthotonus | Canada Vigilance: 1 | Canada Vigilance | |
| 81 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 82 | Tetanus | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Trismus | Canada Vigilance: 2 | Canada Vigilance |
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