MetaADEDB 2.0 @ LMMD
regadenoson
(LZPZPHGJDAGEJZ-AKAIJSEGSA-N)
Structure
SMILES
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(nc2N)n1ncc(c1)C(=O)NC
Type(s)
Approved; Investigational
ATC code(s)
C01EB21
Molecular Formula:
C15H18N8O5
Molecular Weight:
390.354
Log P:
-1.4626
Hydrogen Bond Acceptor:
13
Hydrogen Bond Donor:
5
TPSA:
186.46
CAS Number(s):
313348-27-5
Synonym(s)
1.
regadenoson
2.
CVT 3146
3.
CVT-3146
4.
CVT3146
5.
Lexiscan
External Link(s)
MeSHC430916
PubChem Compound219024
BindingDB50119132
ChEBI135613
CHEMBLCHEMBL317052
DrugBankDB06213
DrugCentral2362
IUPHAR/BPS Guide to PHARMACOLOGY5596
KEGGdr:D05711
Therapeutic Target DatabaseD0XE1C
ZINC13818943
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1NauseaFAERS: 304SIDER
US FAERS
2Injection site extravasationFAERS: 302US FAERS
3VomitingFAERS: 265SIDER
US FAERS
4HeadacheFAERS: 199SIDER
US FAERS
5HypotensionFAERS: 175SIDER
US FAERS
6Cardiac ArrestFAERS: 161SIDER
US FAERS
7DizzinessFAERS: 130SIDER
US FAERS
8Chest PainFAERS: 116SIDER
US FAERS
9BradycardiaFAERS: 98SIDER
US FAERS
10TremorFAERS: 80SIDER
US FAERS
11Unresponsive to stimuliFAERS: 71US FAERS
12Injection site painFAERS: 68SIDER
US FAERS
13MalaiseFAERS: 68SIDER
US FAERS
14SyncopeFAERS: 61SIDER
US FAERS
15Chest discomfortFAERS: 59SIDER
US FAERS
16Infusion Site ExtravasationFAERS: 54US FAERS
17Back PainFAERS: 50US FAERS
18Atrioventricular BlockFAERS: 48SIDER
US FAERS
19ExtravasationFAERS: 47US FAERS
20Abdominal discomfortFAERS: 46SIDER
US FAERS
21Myocardial InfarctionFAERS: 44SIDER
US FAERS
22Feeling abnormalFAERS: 42SIDER
US FAERS
23Incorrect drug administration durationFAERS: 41US FAERS
24PresyncopeFAERS: 40US FAERS
25Cerebrovascular accidentFAERS: 38SIDER
US FAERS
26FlushingFAERS: 37SIDER
US FAERS
27MyalgiaFAERS: 36SIDER
US FAERS
28Abdominal PainFAERS: 30SIDER
US FAERS
29WheezingFAERS: 30SIDER
US FAERS
30AstheniaFAERS: 28SIDER
US FAERS
31PainFAERS: 26SIDER
US FAERS
32FatigueFAERS: 25US FAERS
33TachycardiaFAERS: 24SIDER
US FAERS
34Atrial FibrillationFAERS: 23SIDER
US FAERS
35BronchospasmFAERS: 22SIDER
US FAERS
36Drug administration errorFAERS: 22US FAERS
37Incorrect product administration durationFAERS: 21US FAERS
38AnxietyFAERS: 20SIDER
US FAERS
39ChillsFAERS: 20US FAERS
40Infusion site painFAERS: 20US FAERS
41HypersensitivityFAERS: 19SIDER
US FAERS
42Wrong technique in product usage processFAERS: 19US FAERS
43UrticariaFAERS: 18SIDER
US FAERS
44ArthralgiaFAERS: 17SIDER
US FAERS
45Burning sensationFAERS: 17US FAERS
46Respiratory arrestFAERS: 17SIDER
US FAERS
47PallorFAERS: 16SIDER
US FAERS
48Adverse eventFAERS: 15US FAERS
49AphasiaFAERS: 15US FAERS
50Supraventricular tachycardiaFAERS: 15US FAERS
51Wrong technique in drug usage processFAERS: 15US FAERS
52Electrocardiogram abnormalFAERS: 14US FAERS
53Product quality issueFAERS: 14US FAERS
54RetchingFAERS: 14US FAERS
55Acute myocardial infarctionFAERS: 12US FAERS
56Cold sweatFAERS: 12US FAERS
57ErythemaFAERS: 12SIDER
US FAERS
58Musculoskeletal PainFAERS: 12SIDER
US FAERS
59Incorrect dose administeredFAERS: 10US FAERS
60Injection site erythemaFAERS: 10US FAERS
61Mental status changesFAERS: 10US FAERS
62Respiratory distressFAERS: 10SIDER
US FAERS
63Seizure like phenomenaFAERS: 10US FAERS
64CryingFAERS: 9US FAERS
65Depressed Level of ConsciousnessFAERS: 9SIDER
US FAERS
66DiscomfortFAERS: 9SIDER
US FAERS
67Electrocardiogram changeFAERS: 9US FAERS
68Incorrect product storageFAERS: 9US FAERS
69NervousnessFAERS: 9US FAERS
70PruritusFAERS: 9US FAERS
71Feeling ColdFAERS: 8US FAERS
72Limb discomfortFAERS: 8US FAERS
73PalpitationsFAERS: 8SIDER
US FAERS
74Syringe issueFAERS: 8US FAERS
75Ventricular FibrillationFAERS: 8US FAERS
76Musculoskeletal stiffnessFAERS: 7US FAERS
77Neck PainFAERS: 7US FAERS
78SwellingFAERS: 7US FAERS
79Urinary IncontinenceFAERS: 7US FAERS
80Visual ImpairmentFAERS: 7US FAERS
81Accidental exposure to productFAERS: 6US FAERS
82AmnesiaFAERS: 6US FAERS
83AsthmaFAERS: 6SIDER
US FAERS
84Coronary Artery DiseaseFAERS: 6US FAERS
85Drug ineffectiveFAERS: 6US FAERS
86Electrocardiogram ST segment abnormalFAERS: 6US FAERS
87HemiparesisFAERS: 6US FAERS
88Inappropriate schedule of drug administrationFAERS: 6US FAERS
89LethargyFAERS: 6US FAERS
90Sinus bradycardiaFAERS: 6SIDER
US FAERS
91SomnolenceFAERS: 6SIDER
US FAERS
92Administration site extravasationFAERS: 5US FAERS
93Circumstance or information capable of leading to medication errorFAERS: 5US FAERS
94Device malfunctionFAERS: 5US FAERS
95DisorientationFAERS: 5US FAERS
96DysarthriaFAERS: 5US FAERS
97DysgeusiaFAERS: 5SIDER
US FAERS
98Emotional disorderFAERS: 5US FAERS
99IncoherentFAERS: 5US FAERS
100IncontinenceFAERS: 5US FAERS
101Infusion site swellingFAERS: 5US FAERS
102Respiratory DepressionFAERS: 5US FAERS
103RestlessnessFAERS: 5US FAERS
104AngioedemaFAERS: 4SIDER
US FAERS
105Atrial FlutterFAERS: 4SIDER
US FAERS
106Device FailureFAERS: 4US FAERS
107False negative investigation resultFAERS: 4US FAERS
108Feeling jitteryFAERS: 4US FAERS
109Gait inabilityFAERS: 4US FAERS
110Head discomfortFAERS: 4US FAERS
111HemiplegiaFAERS: 4US FAERS
112Incorrect route of drug administrationFAERS: 4US FAERS
113Injection site discomfortFAERS: 4US FAERS
114Peripheral swellingFAERS: 4US FAERS
115Product use issueFAERS: 4US FAERS
116AbasiaFAERS: 3US FAERS
117Altered state of consciousnessFAERS: 3SIDER
US FAERS
118Angina PectorisFAERS: 3SIDER
US FAERS
119Blood glucose decreasedFAERS: 3US FAERS
120Blood glucose increasedFAERS: 3US FAERS
121Blood pressure immeasurableFAERS: 3US FAERS
122Bowel movement irregularityFAERS: 3US FAERS
123ChokingFAERS: 3US FAERS
124Facial paralysisFAERS: 3US FAERS
125HyperventilationFAERS: 3US FAERS
126HypokinesiaFAERS: 3US FAERS
127Injection site bruisingFAERS: 3US FAERS
128Injection site massFAERS: 3US FAERS
129Joint stiffnessFAERS: 3US FAERS
130Lip swellingFAERS: 3US FAERS
131Medical device complicationFAERS: 3US FAERS
132Medication ErrorFAERS: 3US FAERS
133MydriasisFAERS: 3US FAERS
134No adverse eventFAERS: 3US FAERS
135OverdoseFAERS: 3US FAERS
136Product use in unapproved indicationFAERS: 3US FAERS
137StressFAERS: 3US FAERS
138Therapeutic response delayedFAERS: 3US FAERS
139Throat irritationFAERS: 3SIDER
US FAERS
140Troponin increasedFAERS: 3US FAERS
141Unevaluable eventFAERS: 3US FAERS
142Abdominal symptomFAERS: 2US FAERS
143Acute Coronary SyndromeFAERS: 2SIDER
US FAERS
144Administration site swellingFAERS: 2US FAERS
145AgitationFAERS: 2US FAERS
146AlopeciaFAERS: 2US FAERS
147AneurysmFAERS: 2US FAERS
148Blood glucose abnormalFAERS: 2US FAERS
149Blood pressure fluctuationFAERS: 2US FAERS
150Bone painFAERS: 2US FAERS
151CatatoniaFAERS: 2US FAERS
152Choking sensationFAERS: 2US FAERS
153Contrast media reactionFAERS: 2US FAERS
154Deep Vein ThrombosisFAERS: 2US FAERS
155DehydrationFAERS: 2US FAERS
156DyspepsiaFAERS: 2US FAERS
157DysphoniaFAERS: 2US FAERS
158Ejection Fraction DecreasedFAERS: 2US FAERS
159Electrocardiogram ST-T changeFAERS: 2US FAERS
160Expired product administeredFAERS: 2US FAERS
161Eye irritationFAERS: 2US FAERS
162FasciotomyFAERS: 2US FAERS
163FlatulenceFAERS: 2US FAERS
164Foaming at mouthFAERS: 2US FAERS
165ImmobileFAERS: 2US FAERS
166Impaired driving abilityFAERS: 2US FAERS
167Inappropriate affectFAERS: 2US FAERS
168Incorrect drug administration rateFAERS: 2US FAERS
169Infusion site erythemaFAERS: 2US FAERS
170Injection site inflammationFAERS: 2US FAERS
171Injection site irritationFAERS: 2US FAERS
172Intercepted medication errorFAERS: 2US FAERS
173Joint swellingFAERS: 2US FAERS
174MoaningFAERS: 2US FAERS
175Muscle tightnessFAERS: 2US FAERS
176NasopharyngitisFAERS: 2US FAERS
177Pelvic PainFAERS: 2US FAERS
178Physical product label issueFAERS: 2US FAERS
179PneumoniaFAERS: 2US FAERS
180Post procedural complicationFAERS: 2US FAERS
181Procedural complicationFAERS: 2US FAERS
182Product packaging quantity issueFAERS: 2US FAERS
183Product storage errorFAERS: 2US FAERS
184Psychogenic seizureFAERS: 2US FAERS
185Rash erythematousFAERS: 2US FAERS
186RegurgitationFAERS: 2US FAERS
187Scan abnormalFAERS: 2US FAERS
188Secretion dischargeFAERS: 2US FAERS
189Sinus TachycardiaFAERS: 2US FAERS
190SneezingFAERS: 2US FAERS
191VertigoFAERS: 2US FAERS
192Viral upper respiratory tract infectionFAERS: 2US FAERS
193Weight decreasedFAERS: 2US FAERS
194YawningFAERS: 2US FAERS
195nervous system disorderFAERS: 2SIDER
US FAERS
196Accidental overdoseFAERS: 1US FAERS
197Accidental underdoseFAERS: 1US FAERS
198Activities of daily living impairedFAERS: 1US FAERS
199Amphetamines positiveFAERS: 1US FAERS
200AmphetaminesFAERS: 1US FAERS
201Anaphylactic shockFAERS: 1SIDER
US FAERS
202BedriddenFAERS: 1US FAERS
203BlepharospasmFAERS: 1US FAERS
204Blood sodium decreasedFAERS: 1US FAERS
205Blood urine presentFAERS: 1US FAERS
206BruxismFAERS: 1US FAERS
207Carotid pulse decreasedFAERS: 1US FAERS
208CellulitisFAERS: 1US FAERS
209Central pain syndromeFAERS: 1US FAERS
210Cerebral InfarctionFAERS: 1US FAERS
211Chemical injuryFAERS: 1US FAERS
212CholelithiasisFAERS: 1US FAERS
213Circumstance or information capable of leading to device use errorFAERS: 1US FAERS
214Complication associated with deviceFAERS: 1US FAERS
215Contrast media allergyFAERS: 1US FAERS
216Conversion disorderFAERS: 1US FAERS
217Critical IllnessFAERS: 1US FAERS
218CyanosisFAERS: 1US FAERS
219DeafnessFAERS: 1US FAERS
220DeliriumFAERS: 1US FAERS
221DementiaFAERS: 1US FAERS
222Device component issueFAERS: 1US FAERS
223Device dislocationFAERS: 1US FAERS
224Device infusion issueFAERS: 1US FAERS
225Device occlusionFAERS: 1US FAERS
226DiplegiaFAERS: 1US FAERS
227DiplopiaFAERS: 1US FAERS
228DroolingFAERS: 1US FAERS
229Drug effective for unapproved indicationFAERS: 1US FAERS
230DysphemiaFAERS: 1US FAERS
231DystoniaFAERS: 1US FAERS
232Electrocardiogram QRS complexFAERS: 1US FAERS
233Electrocardiogram ST-T segment depressionFAERS: 1US FAERS
234Emotional distressFAERS: 1US FAERS
235Epigastric discomfortFAERS: 1US FAERS
236EpiglottitisFAERS: 1US FAERS
237Erectile dysfunctionFAERS: 1US FAERS
238Euphoric moodFAERS: 1US FAERS
239Eyelid Function DisorderFAERS: 1US FAERS
240Facial PainFAERS: 1US FAERS
241Facial ParesisFAERS: 1US FAERS
242Facial wastingFAERS: 1US FAERS
243False positive investigation resultFAERS: 1US FAERS
244FibromyalgiaFAERS: 1US FAERS
245Fracture painFAERS: 1US FAERS
246GangreneFAERS: 1US FAERS
247Gastrointestinal PainFAERS: 1SIDER
US FAERS
248Gastrointestinal hypomotilityFAERS: 1US FAERS
249General physical condition abnormalFAERS: 1US FAERS
250General physical health deteriorationFAERS: 1US FAERS
251General symptomFAERS: 1US FAERS
252Grip strength decreasedFAERS: 1US FAERS
253Grip strengthFAERS: 1US FAERS
254Head titubationFAERS: 1US FAERS
255Hemiplegic migraineFAERS: 1US FAERS
256HyperkeratosisFAERS: 1US FAERS
257Hypertensive crisisFAERS: 1US FAERS
258Hypertrophic CardiomyopathyFAERS: 1US FAERS
259Hyporesponsive to stimuliFAERS: 1US FAERS
260Immediate post-injection reactionFAERS: 1US FAERS
261InfarctionFAERS: 1US FAERS
262Infusion site irritationFAERS: 1US FAERS
263Infusion site reactionFAERS: 1US FAERS
264Infusion site urticariaFAERS: 1US FAERS
265Injection Site ReactionFAERS: 1US FAERS
266Injection site injuryFAERS: 1US FAERS
267Intercepted wrong patient selectedFAERS: 1US FAERS
268Intervertebral disc disorderFAERS: 1US FAERS
269Labile blood pressureFAERS: 1US FAERS
270Loss of personal independence in daily activitiesFAERS: 1US FAERS
271Lower respiratory tract infectionFAERS: 1US FAERS
272Memory impairmentFAERS: 1US FAERS
273MenorrhagiaFAERS: 1US FAERS
274MetrorrhagiaFAERS: 1US FAERS
275Migraine with AuraFAERS: 1US FAERS
276MonoplegiaFAERS: 1US FAERS
277Multiple SclerosisFAERS: 1US FAERS
278Multiple sclerosis relapseFAERS: 1US FAERS
279Muscle FatigueFAERS: 1US FAERS
280Muscle RigidityFAERS: 1US FAERS
281MyoclonusFAERS: 1US FAERS
282NarcolepsyFAERS: 1US FAERS
283NephrolithiasisFAERS: 1US FAERS
284NeuralgiaFAERS: 1US FAERS
285Nonspecific reactionFAERS: 1US FAERS
286ObstructionFAERS: 1US FAERS
287Oral pruritusFAERS: 1US FAERS
288Oropharyngeal discomfortFAERS: 1US FAERS
289PancreatitisFAERS: 1US FAERS
290Panic DisorderFAERS: 1US FAERS
291PhlebitisFAERS: 1US FAERS
292PhotophobiaFAERS: 1US FAERS
293Physical disabilityFAERS: 1US FAERS
294Procedural hypertensionFAERS: 1US FAERS
295Procedural nauseaFAERS: 1US FAERS
296Product administration errorFAERS: 1US FAERS
297Product container issueFAERS: 1US FAERS
298Product measured potency issueFAERS: 1US FAERS
299Product packaging issueFAERS: 1US FAERS
300Product sterility lackingFAERS: 1US FAERS
301PsoriasisFAERS: 1US FAERS
302Pulmonary EmbolismFAERS: 1US FAERS
303Respiratory FailureFAERS: 1US FAERS
304Restless Legs SyndromeFAERS: 1US FAERS
305Retinal Artery OcclusionFAERS: 1US FAERS
306ScreamingFAERS: 1US FAERS
307SepsisFAERS: 1US FAERS
308Sick Sinus SyndromeFAERS: 1US FAERS
309Sinus ArrhythmiaFAERS: 1US FAERS
310Skin irritationFAERS: 1US FAERS
311Slow response to stimuliFAERS: 1US FAERS
312Slow speechFAERS: 1US FAERS
313Spinal StenosisFAERS: 1US FAERS
314Therapeutic response unexpectedFAERS: 1US FAERS
315ThirstFAERS: 1US FAERS
316Thrombosis in deviceFAERS: 1US FAERS
317ThrombosisFAERS: 1US FAERS
318Tongue erythemaFAERS: 1US FAERS
319ToothacheFAERS: 1US FAERS
320TrismusFAERS: 1US FAERS
321Urge IncontinenceFAERS: 1US FAERS
322Urinary tract infectionFAERS: 1US FAERS
323VIIth nerve paralysisFAERS: 1US FAERS
324Venous thrombosis limbFAERS: 1US FAERS
325Ventricular dyssynchronyFAERS: 1US FAERS
326Vital functions abnormalFAERS: 1US FAERS
327Wrong technique in device usage processFAERS: 1US FAERS
328Bronchial HyperreactivitySIDER
329BronchoconstrictionSIDER
330Cardiac FlutterSIDER
331DermatitisSIDER
332Ear and labyrinth disordersSIDER
333Eye painSIDER
334Gastrointestinal discomfortSIDER
335Hypotension symptomaticSIDER
336Musculoskeletal discomfortSIDER
337Nodal blockSIDER
338ShockSIDER
339Supraventricular tachyarrhythmiaSIDER
340TinnitusSIDER
341Vasodilation procedureSIDER
342VasodilationSIDER
343Ventricular arrhythmiaSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.