proxymetacaine
(KCLANYCVBBTKTO-UHFFFAOYSA-N)
Structure
- SMILES
- CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC
- Type(s)
- Approved; Vet_approved
- ATC code(s)
- S01HA04
- Molecular Formula:
- C16H26N2O3
- Molecular Weight:
- 294.389
- Log P:
- 3.1374
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 1
- TPSA:
- 64.79
- CAS Number(s):
- 499-67-2
Synonym(s)
1.
proxymetacaine
2.
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
3.
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride
4.
AK-Taine
5.
Alcaine
6.
Chibro-Kerakain
7.
Kainair
8.
Kéracaine
9.
Minims Proxymetacaine Hydrochloride
10.
Ocu-Caine
11.
Ophthaine
12.
Ophthetic
13.
Parcaine
14.
Proparakain-POS
15.
benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester
16.
benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride*benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride
17.
proparacaine
18.
proparacaine HCl
19.
proparacaine hydrochloride
20.
proxymetacaine hydrochloride
21.
proxymetacaine monohydrochloride
22.
proxymethacaine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug abuse | FAERS: 49 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Eye pain | FAERS: 36 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Corneal epithelium defect | FAERS: 35 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 4 | Keratopathy | FAERS: 28 | US FAERS | |
| 5 | Photophobia | FAERS: 27 | US FAERS | |
| 6 | Hypopyon | FAERS: 26 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 7 | Intentional product misuse | FAERS: 10 | US FAERS | |
| 8 | Persistent corneal epithelial defect | FAERS: 10 | US FAERS | |
| 9 | Corneal Opacity | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Corneal Perforation | FAERS: 7 | US FAERS | |
| 11 | Corneal leukoma | FAERS: 7 | US FAERS | |
| 12 | Toxicity to various agents | FAERS: 7 | US FAERS | |
| 13 | Corneal thinning | FAERS: 6 | US FAERS | |
| 14 | Corneal erosion | FAERS: 5 | US FAERS | |
| 15 | Eye irritation | FAERS: 4 | US FAERS | |
| 16 | Syncope | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 17 | Blepharospasm | FAERS: 3 | US FAERS | |
| 18 | Blindness | FAERS: 3 | US FAERS | |
| 19 | Chemical eye injury | FAERS: 3 | US FAERS | |
| 20 | Keratitis | FAERS: 3 Canada Vigilance: 3 | 4232838 | CTD SIDER Canada Vigilance US FAERS |
| 21 | Tremor | FAERS: 3 | US FAERS | |
| 22 | Asthenia | FAERS: 2 | US FAERS | |
| 23 | Dizziness | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 24 | Drug Dependence | FAERS: 2 | US FAERS | |
| 25 | Drug ineffective | FAERS: 2 | US FAERS | |
| 26 | Hypersensitivity | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 27 | Nausea | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 28 | Necrosis | FAERS: 2 | SIDER US FAERS | |
| 29 | Vomiting | FAERS: 2 | US FAERS | |
| 30 | Acanthamoeba Infection | FAERS: 1 | US FAERS | |
| 31 | Acanthamoeba Keratitis | FAERS: 1 | US FAERS | |
| 32 | Amniotic membrane graft | FAERS: 1 | US FAERS | |
| 33 | Anxiety | FAERS: 1 | US FAERS | |
| 34 | Application site reaction | FAERS: 1 | US FAERS | |
| 35 | Blepharitis | FAERS: 1 | US FAERS | |
| 36 | Bradycardia | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 37 | Chest discomfort | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 38 | Chills | FAERS: 1 | US FAERS | |
| 39 | Completed Suicide | FAERS: 1 | US FAERS | |
| 40 | Conjunctivitis | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 41 | Corneal Scar | FAERS: 1 | US FAERS | |
| 42 | Drug abuser | FAERS: 1 | US FAERS | |
| 43 | Emotional distress | FAERS: 1 | US FAERS | |
| 44 | Endophthalmitis | FAERS: 1 | US FAERS | |
| 45 | Eye allergy | FAERS: 1 | US FAERS | |
| 46 | Eye excision | FAERS: 1 | US FAERS | |
| 47 | Eyelids pruritus | FAERS: 1 | US FAERS | |
| 48 | Glaucoma | FAERS: 1 | 9563635 | CTD US FAERS |
| 49 | Hypotension | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 50 | Infectious crystalline keratopathy | FAERS: 1 | US FAERS | |
| 51 | Iritis | FAERS: 1 | SIDER US FAERS | |
| 52 | Lens dislocation | FAERS: 1 | US FAERS | |
| 53 | Malaise | FAERS: 1 | US FAERS | |
| 54 | Pain | FAERS: 1 | 19897799 | CTD SIDER US FAERS |
| 55 | Presyncope | FAERS: 1 | US FAERS | |
| 56 | Product quality issue | FAERS: 1 | US FAERS | |
| 57 | Punctate keratitis | FAERS: 1 | US FAERS | |
| 58 | Purulent discharge | FAERS: 1 | US FAERS | |
| 59 | Shock | FAERS: 1 | US FAERS | |
| 60 | Thirst | FAERS: 1 | US FAERS | |
| 61 | Throat irritation | FAERS: 1 | US FAERS | |
| 62 | Visual Impairment | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 63 | Visual disturbance | FAERS: 1 | US FAERS | |
| 64 | Vitreous prolapse | FAERS: 1 | US FAERS | |
| 65 | Apnea | 19897799 | CTD | |
| 66 | Bacterial Infections | 12669766 | CTD | |
| 67 | Cold sweat | Canada Vigilance: 1 | Canada Vigilance | |
| 68 | Conjunctival congestion | SIDER | ||
| 69 | Descemetitis | SIDER | ||
| 70 | Epilepsy | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Lacrimation | SIDER | ||
| 72 | Mydriasis | SIDER | ||
| 73 | Ocular Hypertension | 9563635 | CTD | |
| 74 | Pallor | Canada Vigilance: 3 | Canada Vigilance | |
| 75 | Pruritus | Canada Vigilance: 1 | Canada Vigilance | |
| 76 | Seizures | 19897799 | CTD | |
| 77 | Stupor | Canada Vigilance: 1 | Canada Vigilance |
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