Ioxaglic Acid
(HIEBCAZLQQSNKK-UHFFFAOYSA-M)
Structure
- SMILES
- CNCC(C(C(C(CO)O)O)O)O.OCCNC(=O)c1c(I)c(NC(=O)CNC(=O)c2c(I)c(C(=O)NC)c(c(c2I)N(C(=O)C)C)I)c(c(c1I)C(=O)O)I.OCCNC(=O)c1c(I)c(NC(=O)CNC(=O)c2c(I)c(C(=O)NC)c(c(c2I)N(C(=O)C)C)I)c(c(c1I)C(=O)[O-])I.[Na+]
- Molecular Formula:
- C55H58I12N11NaO21
- Molecular Weight:
- 2754.950
- Log P:
- 5.0799
- Hydrogen Bond Acceptor:
- 32
- Hydrogen Bond Donor:
- 17
- TPSA:
- 504.49
- CAS Number(s):
- N/A
Synonym(s)
1.
Ioxaglic Acid
2.
Ioxaglate
3.
Ioxaglate Meglumine
4.
Ioxaglate Sodium
5.
Hexabrix
6.
Ioxaglic Acid Monosodium Salt
7.
Ioxaglic Acid, Calcium Salt (2:1)
8.
Methylglucamine Ioxaglate
9.
P-286 (Contrast Media)
10.
P286 (Contrast Media)
11.
Ioxaglate, Methylglucamine
12.
Meglumine, Ioxaglate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Nausea | FAERS: 22 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 2 | Hypotension | FAERS: 17 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Hypersensitivity | FAERS: 16 | US FAERS | |
| 4 | Pruritus | FAERS: 16 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 5 | Anaphylactic shock | FAERS: 14 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 6 | Myoclonus | FAERS: 12 | US FAERS | |
| 7 | Erythema | FAERS: 9 Canada Vigilance: 2 | Canada Vigilance OFFSIDES US FAERS | |
| 8 | Vomiting | FAERS: 9 | US FAERS | |
| 9 | Somnolence | FAERS: 8 | US FAERS | |
| 10 | Status Epilepticus | FAERS: 8 | OFFSIDES US FAERS | |
| 11 | Urticaria | FAERS: 8 Canada Vigilance: 63 | Canada Vigilance US FAERS | |
| 12 | Bronchospasm | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Drug administration error | FAERS: 7 | OFFSIDES US FAERS | |
| 14 | Malaise | FAERS: 7 | US FAERS | |
| 15 | Bradycardia | FAERS: 6 | OFFSIDES US FAERS | |
| 16 | Shock | FAERS: 6 | US FAERS | |
| 17 | Angioedema | FAERS: 5 | OFFSIDES US FAERS | |
| 18 | Chills | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 19 | Wrong drug administered | FAERS: 5 | OFFSIDES US FAERS | |
| 20 | Chest Pain | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Flushing | FAERS: 4 | US FAERS | |
| 22 | Formication | FAERS: 4 | OFFSIDES US FAERS | |
| 23 | Headache | FAERS: 4 | US FAERS | |
| 24 | Post procedural complication | FAERS: 4 | US FAERS | |
| 25 | Rheumatoid Arthritis | FAERS: 4 | US FAERS | |
| 26 | Sneezing | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 27 | Abdominal Pain | FAERS: 3 | US FAERS | |
| 28 | Arthralgia | FAERS: 3 | US FAERS | |
| 29 | Back Pain | FAERS: 3 | US FAERS | |
| 30 | Cold sweat | FAERS: 3 | OFFSIDES US FAERS | |
| 31 | Cyanosis | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 32 | Hypoxia | FAERS: 3 | OFFSIDES US FAERS | |
| 33 | Incorrect route of drug administration | FAERS: 3 | US FAERS | |
| 34 | Rash erythematous | FAERS: 3 | US FAERS | |
| 35 | Rhinitis | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance OFFSIDES US FAERS | |
| 36 | Skin irritation | FAERS: 3 | US FAERS | |
| 37 | Agitation | FAERS: 2 | US FAERS | |
| 38 | Angle Closure Glaucoma | FAERS: 2 | OFFSIDES US FAERS | |
| 39 | Anuria | FAERS: 2 | OFFSIDES US FAERS | |
| 40 | Atrial Fibrillation | FAERS: 2 | US FAERS | |
| 41 | Atrioventricular Block | FAERS: 2 | OFFSIDES US FAERS | |
| 42 | Conjunctivitis | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 43 | Contrast media reaction | FAERS: 2 | US FAERS | |
| 44 | Dysphonia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 45 | Epilepsy | FAERS: 2 | US FAERS | |
| 46 | Eye pain | FAERS: 2 | OFFSIDES US FAERS | |
| 47 | Incontinence | FAERS: 2 | OFFSIDES US FAERS | |
| 48 | Inflammation | FAERS: 2 | US FAERS | |
| 49 | Laryngitis | FAERS: 2 | US FAERS | |
| 50 | Latent tetany | FAERS: 2 | OFFSIDES US FAERS | |
| 51 | Medication Error | FAERS: 2 | US FAERS | |
| 52 | Meningeal disorder | FAERS: 2 | OFFSIDES US FAERS | |
| 53 | Oropharyngeal discomfort | FAERS: 2 | US FAERS | |
| 54 | Pelvic Pain | FAERS: 2 | US FAERS | |
| 55 | Respiratory distress | FAERS: 2 | US FAERS | |
| 56 | Synovitis | FAERS: 2 | OFFSIDES US FAERS | |
| 57 | Tachycardia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 58 | Tremor | FAERS: 2 | US FAERS | |
| 59 | Visual Impairment | FAERS: 2 | US FAERS | |
| 60 | Accidental exposure | FAERS: 1 | US FAERS | |
| 61 | Alanine Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 62 | Aldolase increased | FAERS: 1 | US FAERS | |
| 63 | Altered state of consciousness | FAERS: 1 | OFFSIDES US FAERS | |
| 64 | Amnesia | FAERS: 1 | US FAERS | |
| 65 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 66 | Asthenia | FAERS: 1 | US FAERS | |
| 67 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 68 | Blood immunoglobulin E increased | FAERS: 1 | US FAERS | |
| 69 | Brain scan abnormal | FAERS: 1 | US FAERS | |
| 70 | Cerebral disorder | FAERS: 1 | OFFSIDES US FAERS | |
| 71 | Cerebral hypoperfusion | FAERS: 1 | US FAERS | |
| 72 | Chest discomfort | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 73 | Distributive shock | FAERS: 1 | US FAERS | |
| 74 | Drug toxicity | FAERS: 1 | US FAERS | |
| 75 | Electrocardiogram ST segment abnormal | FAERS: 1 | US FAERS | |
| 76 | Encephalitis | FAERS: 1 | US FAERS | |
| 77 | Eosinophilia | FAERS: 1 | US FAERS | |
| 78 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 79 | Extravasation | FAERS: 1 | US FAERS | |
| 80 | Eye irritation | FAERS: 1 | US FAERS | |
| 81 | Hypertensive crisis | FAERS: 1 | US FAERS | |
| 82 | Immature respiratory system | FAERS: 1 | US FAERS | |
| 83 | Injection site joint pain | FAERS: 1 | US FAERS | |
| 84 | Intentional drug misuse | FAERS: 1 | OFFSIDES US FAERS | |
| 85 | Latex allergy | FAERS: 1 | OFFSIDES US FAERS | |
| 86 | Lip swelling | FAERS: 1 | US FAERS | |
| 87 | Lymphocytic infiltration | FAERS: 1 | US FAERS | |
| 88 | Muscle enzyme increased | FAERS: 1 | US FAERS | |
| 89 | Neurological decompensation | FAERS: 1 | US FAERS | |
| 90 | Nystagmus | FAERS: 1 | US FAERS | |
| 91 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 92 | Pain | FAERS: 1 | US FAERS | |
| 93 | Papule | FAERS: 1 | US FAERS | |
| 94 | Product quality issue | FAERS: 1 | US FAERS | |
| 95 | Purpura | FAERS: 1 | US FAERS | |
| 96 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 97 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 98 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 99 | Respiratory tract irritation | FAERS: 1 | US FAERS | |
| 100 | Sepsis | FAERS: 1 | US FAERS | |
| 101 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 102 | Thrombosis | FAERS: 1 | US FAERS | |
| 103 | Ventricular Fibrillation | FAERS: 1 | US FAERS | |
| 104 | Vertigo | FAERS: 1 | US FAERS | |
| 105 | Wheezing | FAERS: 1 | US FAERS | |
| 106 | nervous system disorder | FAERS: 1 | US FAERS | |
| 107 | Anaphylactoid Reaction | Canada Vigilance: 5 | Canada Vigilance | |
| 108 | Apathy | OFFSIDES | ||
| 109 | Blood creatine phosphokinase increased | OFFSIDES | ||
| 110 | Blood creatinine increased | Canada Vigilance: 1 | Canada Vigilance | |
| 111 | Cardiac Arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 112 | Cell Death | OFFSIDES | ||
| 113 | Conjunctival deposit | OFFSIDES | ||
| 114 | Contrast media allergy | OFFSIDES | ||
| 115 | Drowsiness | OFFSIDES | ||
| 116 | Incorrect dose administered | OFFSIDES | ||
| 117 | Leukoencephalopathy | OFFSIDES | ||
| 118 | Livedo Reticularis | OFFSIDES | ||
| 119 | Lupus-like syndrome | OFFSIDES | ||
| 120 | Propionibacterium infection | OFFSIDES | ||
| 121 | Pustular psoriasis | OFFSIDES | ||
| 122 | Sjogren's Syndrome | OFFSIDES | ||
| 123 | Tinnitus | Canada Vigilance: 1 | Canada Vigilance |
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