Levomilnacipran
(GJJFMKBJSRMPLA-DZGCQCFKSA-N)
Structure
- SMILES
- NC[C@@H]1C[C@]1(c1ccccc1)C(=O)N(CC)CC
- Type(s)
- Approved; Investigational
- Molecular Formula:
- C15H22N2O
- Molecular Weight:
- 246.348
- Log P:
- 2.4717
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 1
- TPSA:
- 46.33
- CAS Number(s):
- 96847-54-0; 96847-55-1
Synonym(s)
1.
Levomilnacipran
2.
Fetzima
3.
Levomilnacipran Hydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Nausea | FAERS: 23 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 2 | Drug ineffective | FAERS: 17 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 3 | Headache | FAERS: 12 | US FAERS | |
| 4 | Urinary Retention | FAERS: 12 | US FAERS | |
| 5 | Anxiety | FAERS: 10 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 6 | Palpitations | FAERS: 10 | US FAERS | |
| 7 | Dizziness | FAERS: 9 | US FAERS | |
| 8 | Tachycardia | FAERS: 8 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 9 | Constipation | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Urinary hesitation | FAERS: 7 | US FAERS | |
| 11 | Fatigue | FAERS: 6 | US FAERS | |
| 12 | Vomiting | FAERS: 6 | US FAERS | |
| 13 | Agitation | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 14 | Anger | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 15 | Serotonin Syndrome | FAERS: 5 | US FAERS | |
| 16 | Tremor | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 17 | Blood glucose increased | FAERS: 4 | US FAERS | |
| 18 | Completed Suicide | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 19 | Dysuria | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 20 | Feeling abnormal | FAERS: 4 | US FAERS | |
| 21 | Painful ejaculation | FAERS: 4 | US FAERS | |
| 22 | Abdominal discomfort | FAERS: 3 | US FAERS | |
| 23 | Atrial Fibrillation | FAERS: 3 | US FAERS | |
| 24 | Back Pain | FAERS: 3 | US FAERS | |
| 25 | Crying | FAERS: 3 | US FAERS | |
| 26 | Drug withdrawal syndrome | FAERS: 3 | US FAERS | |
| 27 | Expired product administered | FAERS: 3 | US FAERS | |
| 28 | Feeling jittery | FAERS: 3 | US FAERS | |
| 29 | Intentional product misuse | FAERS: 3 | US FAERS | |
| 30 | Malaise | FAERS: 3 | US FAERS | |
| 31 | Visual Impairment | FAERS: 3 | US FAERS | |
| 32 | Abdominal Pain | FAERS: 2 | US FAERS | |
| 33 | Alopecia | FAERS: 2 | US FAERS | |
| 34 | Bladder pain | FAERS: 2 | US FAERS | |
| 35 | Catatonia | FAERS: 2 | US FAERS | |
| 36 | Cerebrovascular accident | FAERS: 2 | US FAERS | |
| 37 | Chest Pain | FAERS: 2 | US FAERS | |
| 38 | Drug dose omission | FAERS: 2 | US FAERS | |
| 39 | Erectile dysfunction | FAERS: 2 | US FAERS | |
| 40 | Flatulence | FAERS: 2 | US FAERS | |
| 41 | Flushing | FAERS: 2 | US FAERS | |
| 42 | Malignant Hypertension | FAERS: 2 | US FAERS | |
| 43 | Muscle tightness | FAERS: 2 | US FAERS | |
| 44 | Myalgia | FAERS: 2 | US FAERS | |
| 45 | Pain | FAERS: 2 | US FAERS | |
| 46 | Paranoia | FAERS: 2 | US FAERS | |
| 47 | Peripheral swelling | FAERS: 2 | US FAERS | |
| 48 | Product substitution issue | FAERS: 2 | US FAERS | |
| 49 | Suicide attempt | FAERS: 2 | US FAERS | |
| 50 | Therapy cessation | FAERS: 2 | US FAERS | |
| 51 | Unevaluable event | FAERS: 2 | US FAERS | |
| 52 | Urticaria | FAERS: 2 | US FAERS | |
| 53 | Vertigo | FAERS: 2 | US FAERS | |
| 54 | Adverse event | FAERS: 1 | US FAERS | |
| 55 | Ageusia | FAERS: 1 | US FAERS | |
| 56 | Alcohol Intolerance | FAERS: 1 | US FAERS | |
| 57 | Amphetamines positive | FAERS: 1 | US FAERS | |
| 58 | Anaphylactoid Reaction | FAERS: 1 | US FAERS | |
| 59 | Angioedema | FAERS: 1 | US FAERS | |
| 60 | Appendicitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 61 | Arthralgia | FAERS: 1 | US FAERS | |
| 62 | Arthritis | FAERS: 1 | US FAERS | |
| 63 | Arthropathy | FAERS: 1 | US FAERS | |
| 64 | Asthenia | FAERS: 1 | US FAERS | |
| 65 | Binge Drinking | FAERS: 1 | US FAERS | |
| 66 | Blood cannabinoids | FAERS: 1 | US FAERS | |
| 67 | Blood cholesterol increased | FAERS: 1 | US FAERS | |
| 68 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 69 | Blood urine present | FAERS: 1 | US FAERS | |
| 70 | Bronchospasm | FAERS: 1 | US FAERS | |
| 71 | Burning sensation | FAERS: 1 | US FAERS | |
| 72 | Cataract | FAERS: 1 | US FAERS | |
| 73 | Chromaturia | FAERS: 1 | US FAERS | |
| 74 | Cystitis | FAERS: 1 | US FAERS | |
| 75 | Dehydration | FAERS: 1 | US FAERS | |
| 76 | Depressed mood | FAERS: 1 | US FAERS | |
| 77 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 78 | Drug ineffective for unapproved indication | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 79 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 80 | Dystonia | FAERS: 1 | US FAERS | |
| 81 | Electrocardiogram change | FAERS: 1 | US FAERS | |
| 82 | Euphoric mood | FAERS: 1 | US FAERS | |
| 83 | Eye irritation | FAERS: 1 | US FAERS | |
| 84 | Eye pain | FAERS: 1 | US FAERS | |
| 85 | Gastrointestinal motility disorder | FAERS: 1 | US FAERS | |
| 86 | Genital pain | FAERS: 1 | US FAERS | |
| 87 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 88 | Impaired work ability | FAERS: 1 | US FAERS | |
| 89 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 90 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 91 | Joint injury | FAERS: 1 | US FAERS | |
| 92 | Joint swelling | FAERS: 1 | US FAERS | |
| 93 | Labile blood pressure | FAERS: 1 | US FAERS | |
| 94 | Memory impairment | FAERS: 1 | US FAERS | |
| 95 | Middle insomnia | FAERS: 1 | US FAERS | |
| 96 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 97 | Mydriasis | FAERS: 1 | US FAERS | |
| 98 | Myoclonus | FAERS: 1 | US FAERS | |
| 99 | Narcolepsy | FAERS: 1 | US FAERS | |
| 100 | Neck Pain | FAERS: 1 | US FAERS | |
| 101 | Nervousness | FAERS: 1 | US FAERS | |
| 102 | Pancreatitis | FAERS: 1 | US FAERS | |
| 103 | Petechiae | FAERS: 1 | US FAERS | |
| 104 | Pneumonia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 105 | Poor quality sleep | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 106 | Post-Traumatic Stress Disorder | FAERS: 1 | US FAERS | |
| 107 | Pregnancy | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 108 | Premature Ejaculation | FAERS: 1 | US FAERS | |
| 109 | Product contamination physical | FAERS: 1 | US FAERS | |
| 110 | Product label issue | FAERS: 1 | US FAERS | |
| 111 | Pruritus | FAERS: 1 | US FAERS | |
| 112 | Pseudoparalysis | FAERS: 1 | US FAERS | |
| 113 | Regurgitation | FAERS: 1 | US FAERS | |
| 114 | Retrograde ejaculation | FAERS: 1 | US FAERS | |
| 115 | Seizure like phenomena | FAERS: 1 | US FAERS | |
| 116 | Somnolence | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 117 | Stillbirth | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 118 | Stress | FAERS: 1 | US FAERS | |
| 119 | Syncope | FAERS: 1 | US FAERS | |
| 120 | Tachyarrhythmia | FAERS: 1 | US FAERS | |
| 121 | Tachyphrenia | FAERS: 1 | US FAERS | |
| 122 | Therapeutic response unexpected | FAERS: 1 | US FAERS | |
| 123 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 124 | Wrong technique in product usage process | FAERS: 1 | US FAERS | |
| 125 | Angina Pectoris | Canada Vigilance: 1 | Canada Vigilance | |
| 126 | Blood testosterone increased | Canada Vigilance: 1 | Canada Vigilance | |
| 127 | Incorrect drug administration rate | Canada Vigilance: 1 | Canada Vigilance | |
| 128 | Myocardial Infarction | Canada Vigilance: 1 | Canada Vigilance | |
| 129 | Overdose | Canada Vigilance: 1 | Canada Vigilance | |
| 130 | Overweight | Canada Vigilance: 1 | Canada Vigilance |
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