MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Reboxetine

(CBQGYUDMJHNJBX-RTBURBONSA-N)

Structure

SMILES: CCOc1ccccc1O[C@H](c1ccccc1)[C@@H]1OCCNC1
Type(s): Approved; Experimental
ATC code(s): N06AX18
Molecular Formula:: C19H23NO3
Molecular Weight:: 313.391
Log P:: 3.5226
Hydrogen Bond Acceptor:: 4
Hydrogen Bond Donor:: 1
TPSA:: 39.72
CAS Number(s):: 71620-89-8; 98769-81-4

Synonym(s)

Reboxetine

2-((2-Ethoxyphenoxy)benzyl)morpholine methanesulfonate

Reboxetine Mesylate

Vestra

External Link(s)

MeSH	D000077593
PubChem Compound	127151
BindingDB	388642
ChEBI	135342
CHEMBL	CHEMBL383921
DrugBank	DB00234
DrugCentral	2361
KEGG	dr:D08472
ZINC	3996032

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Abdominal Pain			SIDER
2	Abuse			OFFSIDES
3	Agitation			SIDER
4	Akathisia			SIDER
5	Alanine Aminotransferase Increased			SIDER
6	Albuminuria			SIDER
7	Alcoholic Intoxication			OFFSIDES
8	Amphetamine-Related Disorders		15207001	CTD
9	Anorectal discomfort			SIDER
10	Anorexia			SIDER
11	Anorgasmia			SIDER
12	Anxiety			SIDER
13	Aphasia			SIDER
14	Asthenia			SIDER
15	Ataxia			OFFSIDES
16	Aura			OFFSIDES
17	Automatism			OFFSIDES
18	Bipolar Disorder		12503843	CTD
19	Blood creatine phosphokinase increased			OFFSIDES
20	Blood creatinine increased			SIDER
21	Blood pressure fluctuation			SIDER
22	Bradycardia			SIDER
23	Brief psychotic disorder, with postpartum onset			OFFSIDES
24	Bronchitis			SIDER
25	Cataplexy			OFFSIDES
26	Cataract operation			OFFSIDES
27	Cheilitis			SIDER
28	Chest Pain			SIDER
29	Chills			SIDER
30	Cocaine-Related Disorders		15799010	CTD
31	Confabulation			OFFSIDES
32	Conjunctivitis			SIDER
33	Constipation			SIDER
34	Decreased Libido			OFFSIDES
35	Dehydration			OFFSIDES SIDER
36	Depressed mood			OFFSIDES
37	Depressive disorder		View details 10610387 10628889 12673616 12866714 16631296 19177168 21916421	CTD
38	Dermatitis			SIDER
39	Diplopia			SIDER
40	Discomfort			SIDER
41	Disturbance in sexual arousal			SIDER
42	Dizziness			OFFSIDES SIDER
43	Drug addict			OFFSIDES
44	Drug exposure during pregnancy			OFFSIDES
45	Drug toxicity			OFFSIDES
46	Duodenal Ulcer			SIDER
47	Dysgeusia			SIDER
48	Dyspareunia			SIDER
49	Dyspepsia			SIDER
50	Dysthymic Disorder			OFFSIDES
51	Dysuria			SIDER
52	Electrocardiogram abnormal			SIDER
53	Electrocardiogram change			SIDER
54	Emotional distress			OFFSIDES
55	Epistaxis			SIDER
56	Erectile dysfunction			SIDER
57	Euphoric mood			SIDER
58	Fatigue			OFFSIDES
59	Fatty Liver			OFFSIDES
60	Feeling abnormal			OFFSIDES SIDER
61	Flank Pain			SIDER
62	Flat affect			OFFSIDES
63	Formication			OFFSIDES
64	Gamma-Glutamyltransferase Increased			OFFSIDES SIDER
65	Gastroenteritis			SIDER
66	Gastrointestinal Pain			SIDER
67	Glaucoma			SIDER
68	Glossitis			SIDER
69	Granulocytosis			OFFSIDES
70	Headache			SIDER
71	Heart Diseases		10628889	CTD
72	Hyperkinesia			SIDER
73	Hyperreflexia			OFFSIDES
74	Hypersensitivity			SIDER
75	Hyperventilation			OFFSIDES SIDER
76	Hypomania	Canada Vigilance: 1		Canada Vigilance OFFSIDES
77	Hyponatremia		17965988	CTD
78	Hypotension, Orthostatic		10628889	CTD
79	Hypotension			SIDER
80	Hypoventilation			SIDER
81	Hypoxia			SIDER
82	Inappropriate affect			OFFSIDES
83	Infection			SIDER
84	Infestation			SIDER
85	Influenza			SIDER
86	Intention tremor			OFFSIDES
87	Left Ventricular Hypertrophy			SIDER
88	Lethargy			OFFSIDES
89	Leukoencephalopathy			OFFSIDES
90	Leukopenia neonatal			OFFSIDES
91	Leukopenia			SIDER
92	Malaise			SIDER
93	Malnutrition			SIDER
94	Mental disorders		16856516	CTD
95	Mutism			OFFSIDES
96	Mydriasis			SIDER
97	Nausea			SIDER
98	Neck Pain			SIDER
99	Negativism			OFFSIDES
100	Nervousness			SIDER
101	Neutrophil count abnormal			OFFSIDES
102	Nuchal Rigidity			SIDER
103	Oculogyric crisis			OFFSIDES
104	Palpitations			SIDER
105	Paranoia			SIDER
106	Pharyngitis			SIDER
107	Pierre Robin Syndrome			OFFSIDES
108	Polyuria			OFFSIDES
109	Rectal fissure			OFFSIDES
110	Rectal tenesmus			SIDER
111	Respiratory Failure			SIDER
112	Retrosternal pain			SIDER
113	Rhinitis			SIDER
114	Risus sardonicus			OFFSIDES
115	Schizophrenia			OFFSIDES
116	Sexual Dysfunction			SIDER
117	Shock			SIDER
118	Sinus Tachycardia			SIDER
119	Sinusitis			SIDER
120	Sleep Initiation and Maintenance Disorders		10628889	CTD
121	Somnolence			SIDER
122	Substance Withdrawal Syndrome		15207001 16631296	CTD
123	Sweating			SIDER
124	Syncope			SIDER
125	Tachycardia			SIDER
126	Tension			SIDER
127	Tinnitus			SIDER
128	Transaminases increased			OFFSIDES
129	Tremor			SIDER
130	Urinary Incontinence			SIDER
131	Urinary Retention		11190365	CTD SIDER
132	Urinary hesitation			SIDER
133	Urinary tract infection			SIDER
134	Urticaria			SIDER
135	Vertigo			SIDER
136	Visual Impairment			SIDER
137	Vomiting			SIDER
138	Weight decreased			SIDER
139	Wolff-Parkinson-White Syndrome			OFFSIDES
140	nervous system disorder			SIDER

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120329