Cefotaxime
(AZZMGZXNTDTSME-JUZDKLSSSA-M)
Structure
- SMILES
- CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])COC(=O)C.[Na+]
- Molecular Formula:
- C16H16N5NaO7S2
- Molecular Weight:
- 477.447
- Log P:
- -1.0472
- Hydrogen Bond Acceptor:
- 14
- Hydrogen Bond Donor:
- 2
- TPSA:
- 229.88
- CAS Number(s):
- 64485-93-4
Synonym(s)
1.
Cefotaxime
2.
Benaxima
3.
Biosint
4.
Cefotaxim
5.
Cefotaxime Sodium
6.
Cefradil
7.
Cephotaxim
8.
Claforan
9.
Fotexina
10.
HR-756
11.
Kendrick
12.
Klaforan
13.
Primafen
14.
Ru-24756
15.
Taporin
16.
HR 756
17.
HR756
18.
Ru 24756
19.
Ru24756
20.
Sodium, Cefotaxime
External Link(s)
| MeSH | D002439 |
| PubChem Compound | 10695961 |
| ChEBI | 3498 |
| CHEMBL | CHEMBL1010 |
| KEGG | cpd:C08113 dr:D00919 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hypotension | FAERS: 9 | US FAERS | |
| 2 | Tachycardia | FAERS: 5 | US FAERS | |
| 3 | Eosinophilia | FAERS: 4 | US FAERS | |
| 4 | Erythema | FAERS: 4 | US FAERS | |
| 5 | Hypersensitivity | FAERS: 4 | US FAERS | |
| 6 | Agitation | FAERS: 3 | US FAERS | |
| 7 | Asphyxia | FAERS: 3 | US FAERS | |
| 8 | Deafness | FAERS: 3 | US FAERS | |
| 9 | Pruritus | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Skin reaction | FAERS: 3 | US FAERS | |
| 11 | Urticaria | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 12 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 13 | Agranulocytosis | FAERS: 2 | US FAERS | |
| 14 | Alanine Aminotransferase Increased | FAERS: 2 | US FAERS | |
| 15 | Altered state of consciousness | FAERS: 2 | US FAERS | |
| 16 | Angina Pectoris | FAERS: 2 | US FAERS | |
| 17 | Clostridium difficile colitis | FAERS: 2 | US FAERS | |
| 18 | Cyanosis | FAERS: 2 | US FAERS | |
| 19 | Disorientation | FAERS: 2 | US FAERS | |
| 20 | Hepatitis | FAERS: 2 | US FAERS | |
| 21 | Lymphocytosis | FAERS: 2 | US FAERS | |
| 22 | Megacolon | FAERS: 2 | US FAERS | |
| 23 | Multi-organ disorder | FAERS: 2 | US FAERS | |
| 24 | Pallor | FAERS: 2 | US FAERS | |
| 25 | Petechiae | FAERS: 2 | US FAERS | |
| 26 | Pneumonia | FAERS: 2 | US FAERS | |
| 27 | Purulence | FAERS: 2 | US FAERS | |
| 28 | Septic Shock | FAERS: 2 | US FAERS | |
| 29 | Shock | FAERS: 2 | US FAERS | |
| 30 | Somnolence | FAERS: 2 | US FAERS | |
| 31 | Stenotrophomonas infection | FAERS: 2 | US FAERS | |
| 32 | Supraventricular tachycardia | FAERS: 2 | US FAERS | |
| 33 | Thrombocytopenia | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 34 | Toxicity to various agents | FAERS: 2 | US FAERS | |
| 35 | X-ray abnormal | FAERS: 2 | US FAERS | |
| 36 | pseudomembranous colitis | FAERS: 2 | US FAERS | |
| 37 | Abdominal rigidity | FAERS: 1 | US FAERS | |
| 38 | Accidental drug intake by child | FAERS: 1 | US FAERS | |
| 39 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 40 | Acute myocardial infarction | FAERS: 1 | US FAERS | |
| 41 | Amylase increased | FAERS: 1 | US FAERS | |
| 42 | Arthralgia | FAERS: 1 | US FAERS | |
| 43 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 44 | Bilirubin conjugated increased | FAERS: 1 | US FAERS | |
| 45 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 46 | Bone pain | FAERS: 1 | US FAERS | |
| 47 | Bradycardia | FAERS: 1 | US FAERS | |
| 48 | Bronchospasm | FAERS: 1 | US FAERS | |
| 49 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 50 | Chest discomfort | FAERS: 1 | US FAERS | |
| 51 | Choking | FAERS: 1 | US FAERS | |
| 52 | Cholestasis | FAERS: 1 | US FAERS | |
| 53 | Clostridium difficile sepsis | FAERS: 1 | US FAERS | |
| 54 | Compression fracture | FAERS: 1 | US FAERS | |
| 55 | Cytolytic hepatitis | FAERS: 1 | US FAERS | |
| 56 | Dehydration | FAERS: 1 | US FAERS | |
| 57 | Disseminated Intravascular Coagulation | FAERS: 1 | US FAERS | |
| 58 | Dry skin | FAERS: 1 | US FAERS | |
| 59 | Dysphonia | FAERS: 1 | US FAERS | |
| 60 | Flushing | FAERS: 1 | US FAERS | |
| 61 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 62 | Hepatic necrosis | FAERS: 1 | US FAERS | |
| 63 | Leukocytosis | FAERS: 1 | US FAERS | |
| 64 | Lip swelling | FAERS: 1 | US FAERS | |
| 65 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 66 | Maternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 67 | Medication Error | FAERS: 1 | US FAERS | |
| 68 | Mouth swelling | FAERS: 1 | US FAERS | |
| 69 | Myalgia | FAERS: 1 | US FAERS | |
| 70 | Nerve injury | FAERS: 1 | US FAERS | |
| 71 | Neutropenia | FAERS: 1 | US FAERS | |
| 72 | Pancreatitis | FAERS: 1 | US FAERS | |
| 73 | Pancytopenia | FAERS: 1 | US FAERS | |
| 74 | Photodermatosis | FAERS: 1 | US FAERS | |
| 75 | Pulmonary Embolism | FAERS: 1 | US FAERS | |
| 76 | Rash erythematous | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 77 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 78 | Serum Sickness | FAERS: 1 | US FAERS | |
| 79 | Splenomegaly | FAERS: 1 | US FAERS | |
| 80 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 81 | Swelling | FAERS: 1 | US FAERS | |
| 82 | Thrombosis | FAERS: 1 | US FAERS | |
| 83 | Vasculitis | FAERS: 1 | US FAERS | |
| 84 | Wrong technique in drug usage process | FAERS: 1 | US FAERS | |
| 85 | jaundice | FAERS: 1 | US FAERS |
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