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找到 234 篇论文

2016

#1 2016

Computational investigation of the interaction mechanism between the estrogen related receptor α and its agonists

作者: Fuxing Li, Xianqiang Sun, Yingchun Cai, Defang Fan, Weihua Li, Yun Tang*, Guixia Liu*

期刊: RSC Adv.

信息: 2016 | 6(96) | 94119-94127

#2 2016

In silico prediction of chemical mechanism of action via an improved network-based inference method

作者: Zengrui Wu, Weiqiang Lu, Dang Wu, Anqi Luo, Hanping Bian, Jie Li, Weihua Li, Guixia Liu, Jin Huang*, Feixiong Cheng, Yun Tang*

期刊: Br. J. Pharmacol.

信息: 2016 | 173(23) | 3372-3385

#3 2016

Network-based identification of microRNAs as potential pharmacogenomic biomarkers for anticancer drugs

作者: Jie Li, Kecheng Lei, Zengrui Wu, Weihua Li, Guixia Liu, Jianwen Liu, Feixiong Cheng, Yun Tang*

期刊: Oncotarget

信息: 2016 | 7(29) | 45584-45596

#4 2016

Interactions of omeprazole-based analogues with cytochrome P450 2C19: a computational study

作者: Junhao Li, Hanwen Du, Zengrui Wu, Haixia Su, Guixia Liu, Yun Tang*, Weihua Li*

期刊: Mol. BioSyst.

信息: 2016 | 12(6) | 1913-1921

#5 2016

SDTNBI: an integrated network and chemoinformatics tool for systematic prediction of drug–target interactions and drug repositioning

作者: Zengrui Wu, Feixiong Cheng, Jie Li, Weihua Li, Guixia Liu, Yun Tang*

期刊: Brief Bioinform.

信息: 2016 | Vol.DOI | 10

#6 2016

Computational insights into different inhibition modes of the κ-opioid receptor with antagonists LY2456302 and JDTic

作者: Jianxin Cheng, Weihua Li, Guixia Liu, Weiliang Zhu, Yun Tang*

期刊: RSC Adv.

信息: 2016 | 6(17) | 13626-13635

#7 2016

Computational insight into conformational states of glucagon-like peptide-1 receptor (GLP-1R) and its binding mode with GLP-1

作者: Juan Zhang, Shikai Gu, Xianqiang Sun, Weihua Li, Yun Tang*, Guixia Liu*

期刊: RSC Adv.

信息: 2016 | 6(16) | 13490-13497

#8 2016

Lee, Yun Tang*

作者: Chen Zhang, Yuan Zhou, Shikai Gu, Zengrui Wu, Wenjie Wu, Changming Liu, Kaidong Wang, Guixia Liu, Weihua Li, Philip W

期刊: In silico prediction of hERG potassium channel blockage by chemical category approaches. Toxicol. Res.

信息: 2016 | 5(2) | 570-582

#9 2016

Effects of protein flexibility and active site water molecules on the prediction of sites of metabolism for cytochrome P450 2C19 substrates

作者: Junhao Li, Jinya Cai, Haixia Su, Hanwen Du, Juan Zhang, Shihui Ding, Guixia Liu, Yun Tang*, Weihua Li*

期刊: Mol. BioSyst.

信息: 2016 | 12(3) | 868-878

2015

#1 2015

Computational insights into inhibitory mechanism of azole compounds against human aromatase

作者: Jinya Cai, Junhao Li, Juan Zhang, Shihui Ding, Guixia Liu, Weihua Li*, Yun Tang*

期刊: RSC Adv.

信息: 2015 | 5(110) | 90871-90880

#2 2015

Mendrick, Yun Tang, Feixiong Cheng

作者: Chen Zhang, Huixiao Hong, Donna L

期刊: Biomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory science. Biomark. Med.

信息: 2015 | 9(11) | 1241-1252

#3 2015

Association between cigarette smoking and Parkinson's disease: A meta-analysis

作者: Xiao Li, Weihua Li, Guixia Liu, Xu Shen, Yun Tang*

期刊: Arch. Gerontol. Geriat.

信息: 2015 | 61(3) | 510-516

#4 2015

Quantitative Regression Models for the Prediction of Chemical Properties by an Efficient Workflow

作者: Yongmin Yin, Congying Xu, Shikai Gu, Weihua Li, Guixia Liu*, Yun Tang*

期刊: Mol. Inform.

信息: 2015 | 34(10) | 679-688

#5 2015

In Silico Estimation of Chemical Carcinogenicity with Binary and Ternary Classification Methods

作者: Xiao Li, Zheng Du, Jie Wang, Zengrui Wu, Weihua Li, Guixia Liu, Xu Shen, Yun Tang*

期刊: Mol. Inform.

信息: 2015 | Vol.34 | 228-235

#6 2015

Residues remote from the binding pocket control the antagonist selectivity towards the corticotropin-releasing factor receptor-1

作者: Xianqiang Sun, Jianxin Cheng, Xu Wang, Yun Tang*, Hans Agren, Yaoquan Tu*

期刊: Scientific Reports

信息: 2015 | Vol.5 | 8066

#7 2015

FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach

作者: Weiqiang Lu, Feixiong Cheng, Jing Jiang, Chen Zhang, Xiaokang Deng, Zhongyu Xu, Shien Zou*, Xu Shen, Yun Tang*, Jin Huang*

期刊: Scientific Reports

信息: 2015 | Vol.5 | 8114

#8 2015

Lee, Yun Tang*

作者: Lu Sun, Chen Zhang, Yingjie Chen, Xiao Li, Shulin Zhuang, Weihua Li, Guixia Liu, Philip W

期刊: In silico prediction of chemical aquatic toxicity with chemical category approaches and substructural alerts. Toxicol. Res.

信息: 2015 | Vol.4 | 452-463

#9 2015

Discovery of New Non-Steroidal Farnesoid X Receptor Modulators Through 3D Shape Similarity Search and Structure-Based Virtual Screening

作者: Lei Wang, Pei Si, Yayun Sheng, Yingjie Chen, Ping Wan, Xu Shen, Yun Tang, Lili Chen*, Weihua Li*

期刊: Chem. Biol. Drug Des.

信息: 2015 | Vol.85 | 481-487

#10 2015

Lee, Yun Tang

作者: Chen Zhang, Feixiong Cheng, Lu Sun, Shulin Zhuang, Weihua Li, Guixia Liu, Philip W

期刊: In silico prediction of chemical toxicity on avian species using chemical category approaches. Chemosphere

信息: 2015 | Vol.122 | 280-287

发表论文

2016

Computational investigation of the interaction mechanism between the estrogen related receptor α and its agonists

In silico prediction of chemical mechanism of action via an improved network-based inference method

Network-based identification of microRNAs as potential pharmacogenomic biomarkers for anticancer drugs

Interactions of omeprazole-based analogues with cytochrome P450 2C19: a computational study

SDTNBI: an integrated network and chemoinformatics tool for systematic prediction of drug–target interactions and drug repositioning

Computational insights into different inhibition modes of the κ-opioid receptor with antagonists LY2456302 and JDTic

Computational insight into conformational states of glucagon-like peptide-1 receptor (GLP-1R) and its binding mode with GLP-1

Lee, Yun Tang*

Effects of protein flexibility and active site water molecules on the prediction of sites of metabolism for cytochrome P450 2C19 substrates

2015

Computational insights into inhibitory mechanism of azole compounds against human aromatase

Mendrick, Yun Tang, Feixiong Cheng

Association between cigarette smoking and Parkinson's disease: A meta-analysis

Quantitative Regression Models for the Prediction of Chemical Properties by an Efficient Workflow

In Silico Estimation of Chemical Carcinogenicity with Binary and Ternary Classification Methods

Residues remote from the binding pocket control the antagonist selectivity towards the corticotropin-releasing factor receptor-1

FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach

Lee, Yun Tang*

Discovery of New Non-Steroidal Farnesoid X Receptor Modulators Through 3D Shape Similarity Search and Structure-Based Virtual Screening

Lee, Yun Tang

年份导航

发表论文

2016

Computational investigation of the interaction mechanism between the estrogen related receptor α and its agonists

In silico prediction of chemical mechanism of action via an improved network-based inference method

Network-based identification of microRNAs as potential pharmacogenomic biomarkers for anticancer drugs

Interactions of omeprazole-based analogues with cytochrome P450 2C19: a computational study

SDTNBI: an integrated network and chemoinformatics tool for systematic prediction of drug–target interactions and drug repositioning

Computational insights into different inhibition modes of the κ-opioid receptor with antagonists LY2456302 and JDTic

Computational insight into conformational states of glucagon-like peptide-1 receptor (GLP-1R) and its binding mode with GLP-1

Lee, Yun Tang*

Effects of protein flexibility and active site water molecules on the prediction of sites of metabolism for cytochrome P450 2C19 substrates

2015

Computational insights into inhibitory mechanism of azole compounds against human aromatase

Mendrick, Yun Tang*, Feixiong Cheng*

Association between cigarette smoking and Parkinson's disease: A meta-analysis

Quantitative Regression Models for the Prediction of Chemical Properties by an Efficient Workflow

In Silico Estimation of Chemical Carcinogenicity with Binary and Ternary Classification Methods

Residues remote from the binding pocket control the antagonist selectivity towards the corticotropin-releasing factor receptor-1

FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach

Lee, Yun Tang*

Discovery of New Non-Steroidal Farnesoid X Receptor Modulators Through 3D Shape Similarity Search and Structure-Based Virtual Screening

Lee*, Yun Tang*

年份导航

Mendrick, Yun Tang, Feixiong Cheng

Lee, Yun Tang