MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

beraprost

(YTCZZXIRLARSET-VJRSQJMHSA-M)

Structure

SMILES: CC#CCC([C@@H](/C=C/[C@H]1[C@H](O)C[C@H]2[C@@H]1c1cccc(c1O2)CCCC(=O)[O-])O)C.[Na+]
Type(s): Investigational
ATC code(s): B01AC19
Molecular Formula:: C24H29NaO5
Molecular Weight:: 420.474
Log P:: 1.9512
Hydrogen Bond Acceptor:: 5
Hydrogen Bond Donor:: 2
TPSA:: 89.82
CAS Number(s):: 88430-50-6; 88475-69-8

Synonym(s)

beraprost

4-(1,2,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyloct-6-yne-1-enyl)-5-cyclopenta(b)benzofuranyl)butyrate

TRK 100

TRK-100

beraprost sodium

External Link(s)

MeSH	C048081
PubChem Compound	23663404
CHEMBL	CHEMBL435883
DrugBank	DB05229

Adverse Drug Event(s)

	Name	Data Source
1	Abdominal Abscess	OFFSIDES
2	Acidosis	OFFSIDES
3	Alanine Aminotransferase Increased	OFFSIDES
4	Altered state of consciousness	OFFSIDES
5	Anorexia	OFFSIDES
6	Anuria	OFFSIDES
7	Asterixis	OFFSIDES
8	Atrial Flutter	OFFSIDES
9	Autoimmune thrombocytopenia	OFFSIDES
10	Blood Glucose	OFFSIDES
11	Blood alkaline phosphatase increased	OFFSIDES
12	Blood creatine phosphokinase MB	OFFSIDES
13	Blood creatine phosphokinase increased	OFFSIDES
14	Blood creatinine decreased	OFFSIDES
15	Blood creatinine increased	OFFSIDES
16	Blood glucose decreased	OFFSIDES
17	Blood glucose fluctuation	OFFSIDES
18	Blood immunoglobulin E	OFFSIDES
19	Blood lactate dehydrogenase increased	OFFSIDES
20	Blood phosphorus increased	OFFSIDES
21	Blood potassium increased	OFFSIDES
22	Blood pressure inadequately controlled	OFFSIDES
23	Blood urea increased	OFFSIDES
24	Blood urine present	OFFSIDES
25	Body Temperature	OFFSIDES
26	Bone lesion	OFFSIDES
27	Brain natriuretic peptide increased	OFFSIDES
28	Breast cancer recurrent	OFFSIDES
29	Bronchiectasis	OFFSIDES
30	Bronchoscopy abnormal	OFFSIDES
31	Cataplexy	OFFSIDES
32	Cheilitis	OFFSIDES
33	Chemotherapeutic drug level increased	OFFSIDES
34	Chronic respiratory failure	OFFSIDES
35	Cirrhosis	OFFSIDES
36	Coagulation test abnormal	OFFSIDES
37	Cold sweat	OFFSIDES
38	Creatinine renal clearance decreased	OFFSIDES
39	Dehydration	OFFSIDES
40	Dental abscess	OFFSIDES
41	Depressed Level of Consciousness	OFFSIDES
42	Disseminated Intravascular Coagulation	OFFSIDES
43	Dyslalia	OFFSIDES
44	Dysuria	OFFSIDES
45	Eczema	OFFSIDES
46	Electrocardiogram ST-T change	OFFSIDES
47	Encephalitis	OFFSIDES
48	Eosinophilic Pneumonia	OFFSIDES
49	Epididymitis	OFFSIDES
50	Erythema Multiforme	OFFSIDES
51	Erythema	OFFSIDES
52	Extremity necrosis	OFFSIDES
53	Feeling Cold	OFFSIDES
54	Femoral artery occlusion	OFFSIDES
55	Gamma-Glutamyltransferase Increased	OFFSIDES
56	Gastric Lavage	OFFSIDES
57	Gastrointestinal perforation	OFFSIDES
58	Hepatic congestion	OFFSIDES
59	Histiocytosis haematophagic	OFFSIDES
60	Hypophagia	OFFSIDES
61	Hypoxia	OFFSIDES
62	Impaired gastric emptying	OFFSIDES
63	Infection	OFFSIDES
64	Infusion site infection	OFFSIDES
65	Leukopenia neonatal	OFFSIDES
66	Lip erosion	OFFSIDES
67	Lymphocyte stimulation test positive	OFFSIDES
68	Mesenteric vascular insufficiency	OFFSIDES
69	Myoglobin urine present	OFFSIDES
70	Overdose	OFFSIDES
71	Percutaneous Coronary Intervention	OFFSIDES
72	Peritonitis	OFFSIDES
73	Pneumothorax	OFFSIDES
74	Protein total decreased	OFFSIDES
75	Prothrombin level decreased	OFFSIDES
76	Pupillary light reflex tests abnormal	OFFSIDES
77	Rebound effect	OFFSIDES
78	Respiratory Failure	OFFSIDES
79	Right ventricular systolic pressure increased	OFFSIDES
80	Sequestrectomy	OFFSIDES
81	Stevens-Johnson Syndrome	OFFSIDES
82	Stridor	OFFSIDES
83	Thrombotic stroke	OFFSIDES
84	Upper respiratory tract inflammation	OFFSIDES
85	Urine osmolarity increased	OFFSIDES
86	Urobilin urine present	OFFSIDES
87	Vascular calcification	OFFSIDES
88	Ventricular Fibrillation	OFFSIDES
89	White blood cell count abnormal	OFFSIDES
90	Wound Infection	OFFSIDES
91	Yawning	OFFSIDES

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