MetaADEDB 2.0 @ LMMD
mosapride
(YPELFRMCRYSPKZ-UHFFFAOYSA-N)
Structure
SMILES
CCOc1cc(N)c(cc1C(=O)NCC1OCCN(C1)Cc1ccc(cc1)F)Cl
Type(s)
Investigational
Molecular Formula:
C21H25ClFN3O3
Molecular Weight:
421.893
Log P:
4.0008
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
76.82
CAS Number(s):
112885-41-3; 1246820-66-5
Synonym(s)
1.
mosapride
2.
4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide
3.
AS 4370
4.
AS-4370
5.
mosapride citrate
External Link(s)
MeSHC062720
PubChem Compound119584
BindingDB94630
50011327
ChEBI94373
CHEMBLCHEMBL60889
DrugBankDB11675
DrugCentral1848
IUPHAR/BPS Guide to PHARMACOLOGY242
KEGGdr:D08236
Therapeutic Target DatabaseD06PZN
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Accidental overdoseOFFSIDES
2Acute bronchitisOFFSIDES
3Alanine Aminotransferase IncreasedOFFSIDES
4Altered state of consciousnessOFFSIDES
5AmphetaminesOFFSIDES
6AnorexiaOFFSIDES
7Antimicrobial susceptibility test resistantOFFSIDES
8AnuriaOFFSIDES
9AscitesOFFSIDES
10AsterixisOFFSIDES
11AtelectasisOFFSIDES
12AuraOFFSIDES
13Autoantibody positiveOFFSIDES
14Bile duct cancer stage IIIOFFSIDES
15Bipolar I disorderOFFSIDES
16Blood albumin decreasedOFFSIDES
17Blood alkaline phosphatase increasedOFFSIDES
18Blood amylase increasedOFFSIDES
19Blood chloride decreasedOFFSIDES
20Blood chloride increasedOFFSIDES
21Blood creatine phosphokinase increasedOFFSIDES
22Blood creatinine increasedOFFSIDES
23Blood lactate dehydrogenase increasedOFFSIDES
24Blood potassium decreasedOFFSIDES
25Blood potassium increasedOFFSIDES
26Blood sodium increasedOFFSIDES
27Blood sodiumOFFSIDES
28Blood urea increasedOFFSIDES
29Blood uric acidOFFSIDES
30Bone marrow depressionOFFSIDES
31Brain natriuretic peptide increasedOFFSIDES
32BronchopneumoniaOFFSIDES
33Cancer PainOFFSIDES
34Cardiac DeathOFFSIDES
35Catheter site painOFFSIDES
36CholangiolitisOFFSIDES
37Cold sweatOFFSIDES
38Contralateral breast cancerOFFSIDES
39Depressed Level of ConsciousnessOFFSIDES
40Diabetes mellitus inadequate controlOFFSIDES
41Disseminated Intravascular CoagulationOFFSIDES
42Duodenal perforationOFFSIDES
43DyslaliaOFFSIDES
44Dyspepsia15943844
15943846
17845684		CTD
45Eyelid Function DisorderOFFSIDES
46Gamma-Glutamyltransferase IncreasedOFFSIDES
47Gastrointestinal motility disorderOFFSIDES
48Gastrointestinal perforationOFFSIDES
49Gaze palsyOFFSIDES
50Hepatitis BOFFSIDES
51Hepatitis C antibody positiveOFFSIDES
52HiccoughOFFSIDES
53HydropneumothoraxOFFSIDES
54HypochondriasisOFFSIDES
55HypokinesiaOFFSIDES
56HypophagiaOFFSIDES
57Hypothalamo-pituitary disorderOFFSIDES
58Irritable Bowel Syndrome23330973CTD
59Leukopenia neonatalOFFSIDES
60LipaseOFFSIDES
61Long QT SyndromeOFFSIDES
62Lymphangiosis carcinomatosaOFFSIDES
63Lymphocyte count decreasedOFFSIDES
64Lymphocyte stimulation test positiveOFFSIDES
65Malignant neoplasm progressionOFFSIDES
66Myoglobin urine presentOFFSIDES
67NasopharyngitisOFFSIDES
68NauseaOFFSIDES
69Neuroleptic Malignant SyndromeOFFSIDES
70Neutrophil count decreasedOFFSIDES
71Oral administration complicationOFFSIDES
72OverdoseOFFSIDES
73Pancreatic carcinoma recurrentOFFSIDES
74PeriodontitisOFFSIDES
75PleurodesisOFFSIDES
76Portal Vein ThrombosisOFFSIDES
77Protein total decreasedOFFSIDES
78Pseudomonal sepsisOFFSIDES
79Pupillary light reflex tests abnormalOFFSIDES
80PyelonephritisOFFSIDES
81PyuriaOFFSIDES
82Respiratory FailureOFFSIDES
83RhabdomyolysisOFFSIDES
84Sclerosing encapsulating peritonitisOFFSIDES
85Thoracic cavity drainageOFFSIDES
86Thrombosis in deviceOFFSIDES
87Torsades de Pointes11227957CTD
88Ventricular FibrillationOFFSIDES
89Water IntoxicationOFFSIDES
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