Codeine
(WUXLCJZUUHIXFY-FFHNEAJVSA-N)
Structure
- SMILES
- OP(=O)(O)O.COc1ccc2c3c1O[C@@H]1[C@@]43CCN([C@H](C2)[C@@H]4C=C[C@@H]1O)C
- Molecular Formula:
- C18H24NO7P
- Molecular Weight:
- 397.359
- Log P:
- 0.5104
- Hydrogen Bond Acceptor:
- 8
- Hydrogen Bond Donor:
- 4
- TPSA:
- 129.5
- CAS Number(s):
- 52-28-8
Synonym(s)
1.
Codeine
2.
Ardinex
3.
Codeine Phosphate
4.
Isocodeine
5.
N-Methylmorphine
6.
N Methylmorphine
External Link(s)
| MeSH | D003061 |
| PubChem Compound | 5359227 |
| CHEMBL | CHEMBL1159819 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Overdose | FAERS: 4 | US FAERS | |
| 2 | Nausea | FAERS: 3 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 3 | Pancreatitis | FAERS: 3 | US FAERS | |
| 4 | Toxicity to various agents | FAERS: 3 | US FAERS | |
| 5 | Vomiting | FAERS: 3 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 6 | Carbon Monoxide Poisoning | FAERS: 2 | US FAERS | |
| 7 | Completed Suicide | FAERS: 2 | US FAERS | |
| 8 | Constipation | FAERS: 2 | US FAERS | |
| 9 | Malaise | FAERS: 2 | US FAERS | |
| 10 | Abdominal Pain | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 11 | Accidental overdose | FAERS: 1 | US FAERS | |
| 12 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 13 | Anaphylactic shock | FAERS: 1 | US FAERS | |
| 14 | Chest Pain | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 15 | Drug Dependence | FAERS: 1 | US FAERS | |
| 16 | Dystonia | FAERS: 1 | US FAERS | |
| 17 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 18 | Hemiparesis | FAERS: 1 | US FAERS | |
| 19 | Hyporesponsive to stimuli | FAERS: 1 | US FAERS | |
| 20 | Miliaria | FAERS: 1 | US FAERS | |
| 21 | Neck Pain | FAERS: 1 | US FAERS | |
| 22 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 23 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 24 | Sepsis | FAERS: 1 | US FAERS | |
| 25 | Sphincter of Oddi Dysfunction | FAERS: 1 | US FAERS | |
| 26 | Syncope | FAERS: 1 | US FAERS | |
| 27 | Urticaria | FAERS: 1 Canada Vigilance: 19 | Canada Vigilance US FAERS | |
| 28 | Abdominal discomfort | Canada Vigilance: 3 | Canada Vigilance | |
| 29 | Akathisia | Canada Vigilance: 1 | Canada Vigilance | |
| 30 | Angioedema | Canada Vigilance: 3 | Canada Vigilance | |
| 31 | Asthenia | Canada Vigilance: 5 | Canada Vigilance | |
| 32 | Blindness | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Bradycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Bronchospasm | Canada Vigilance: 2 | Canada Vigilance | |
| 35 | Chest discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 36 | Dermatitis | Canada Vigilance: 2 | Canada Vigilance | |
| 37 | Dizziness | Canada Vigilance: 3 | Canada Vigilance | |
| 38 | Dyspepsia | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Erythema | Canada Vigilance: 18 | Canada Vigilance | |
| 40 | Fatigue | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Flushing | Canada Vigilance: 17 | Canada Vigilance | |
| 42 | Hypersensitivity | Canada Vigilance: 1 | Canada Vigilance | |
| 43 | Hypotension | Canada Vigilance: 4 | Canada Vigilance | |
| 44 | Injection Site Reaction | Canada Vigilance: 30 | Canada Vigilance | |
| 45 | Injection site inflammation | Canada Vigilance: 9 | Canada Vigilance | |
| 46 | Nervousness | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Pallor | Canada Vigilance: 1 | Canada Vigilance | |
| 48 | Palpitations | Canada Vigilance: 6 | Canada Vigilance | |
| 49 | Pruritus | Canada Vigilance: 11 | Canada Vigilance | |
| 50 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 51 | Rash erythematous | Canada Vigilance: 21 | Canada Vigilance | |
| 52 | Respiratory arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 53 | Tachycardia | Canada Vigilance: 2 | Canada Vigilance | |
| 54 | Tinnitus | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Urinary Retention | Canada Vigilance: 1 | Canada Vigilance |
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