MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Chlorprothixene

(WSPOMRSOLSGNFJ-AUWJEWJLSA-N)

Structure

SMILES: CN(CC/C=C\1/c2ccccc2Sc2c1cc(Cl)cc2)C
Type(s): Approved; Experimental; Investigational; Withdrawn
ATC code(s): N05AF03
Molecular Formula:: C18H18ClNS
Molecular Weight:: 315.860
Log P:: 5.1880
Hydrogen Bond Acceptor:: 2
Hydrogen Bond Donor:: 0
TPSA:: 28.54
CAS Number(s):: 113-59-7

Synonym(s)

Chlorprothixene

Chlorprotixen

Taractan

External Link(s)

MeSH	D002749
PubChem Compound	667467 667466
BindingDB	50240514
ChEBI	50931
CHEMBL	CHEMBL908
DrugBank	DB01239
DrugCentral	623
KEGG	cpd:C07953 dr:D00790
Therapeutic Target Database	D0B0CP
ZINC	1137

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abasia		OFFSIDES
2	Abuse		OFFSIDES
3	Acne		OFFSIDES
4	Acute kidney injury	7257872	CTD
5	Acute psychosis		OFFSIDES
6	Alanine Aminotransferase Increased		OFFSIDES
7	Alcohol consumption		OFFSIDES
8	Alcohol poisoning		OFFSIDES
9	Anticholinergic Syndrome		OFFSIDES
10	Anxiety		OFFSIDES
11	Aphonia		OFFSIDES
12	Apnea	7270862	CTD
13	Arterial Injury		OFFSIDES
14	Arteriosclerosis		OFFSIDES
15	Aspermia		OFFSIDES
16	Asphyxia		OFFSIDES
17	Atrioventricular Block		OFFSIDES
18	Basal Ganglia Diseases	6016862	CTD
19	Bile Duct Diseases	11669021	CTD
20	Blood creatine phosphokinase increased		OFFSIDES
21	Blood lactate dehydrogenase increased		OFFSIDES
22	Bowel movement irregularity		OFFSIDES
23	Bulbar palsy		OFFSIDES
24	Chemotherapeutic drug level increased		OFFSIDES
25	Cholestasis	11669021	CTD
26	Congenital Hydrocephalus		OFFSIDES
27	Congenital neurological disorder		OFFSIDES
28	Congenital scoliosis		OFFSIDES
29	Demyelination		OFFSIDES
30	Diaphragmatic Hernia		OFFSIDES
31	Drowsiness		OFFSIDES
32	Drug addict		OFFSIDES
33	Drug exposure before pregnancy		OFFSIDES
34	Drug level below therapeutic		OFFSIDES
35	Dysthymic Disorder		OFFSIDES
36	Ear discomfort		OFFSIDES
37	Echocardiogram abnormal		OFFSIDES
38	Epidural lipomatosis		OFFSIDES
39	Epilepsy		OFFSIDES
40	Erectile dysfunction		OFFSIDES
41	Fatigue		OFFSIDES
42	Fever	11669021	CTD
43	Gamma-Glutamyltransferase Increased		OFFSIDES
44	Gastroenteritis		OFFSIDES
45	Gastrointestinal sounds abnormal		OFFSIDES
46	Granulocyte count decreased		OFFSIDES
47	Granulocytosis		OFFSIDES
48	Hallucinations	4834739	CTD
49	Head titubation		OFFSIDES
50	Hemothorax		OFFSIDES
51	Hepatic congestion		OFFSIDES
52	Hypercholesterolemia	11669021	CTD
53	Intentional misuse		OFFSIDES
54	Leukopenia neonatal		OFFSIDES
55	Lysosomal Storage Diseases	28551711	CTD
56	Malaria, Falciparum	16882315	CTD
57	Mental disorders	16856516	CTD
58	Multiple drug overdose		OFFSIDES
59	Multiple drug overdose intentional		OFFSIDES
60	Mycoplasma Infections	10773494	CTD
61	Overdose		OFFSIDES
62	Paranoid Personality Disorder		OFFSIDES
63	Paraparesis		OFFSIDES
64	Personality Change		OFFSIDES
65	Pregnancy Complications	11669021	CTD
66	Pruritus	11669021	CTD
67	Psychotic Disorders	16882315 19708200	CTD
68	Pustular psoriasis		OFFSIDES
69	Retinal pigmentation		OFFSIDES
70	Schizophrenia	1830565	CTD OFFSIDES
71	Seminal vesicular disorder		OFFSIDES
72	Sick Sinus Syndrome		OFFSIDES
73	Somnambulism	453369	CTD
74	Sopor		OFFSIDES
75	Stevens-Johnson Syndrome		OFFSIDES
76	Sudden Cardiac Death		OFFSIDES
77	Sudden death		OFFSIDES
78	Supraventricular tachycardia		OFFSIDES
79	Syncope	7257872	CTD
80	Tardive Dyskinesia		OFFSIDES
81	Teeth brittle		OFFSIDES
82	Tooth Loss		OFFSIDES
83	Transaminases increased		OFFSIDES
84	Ventricular Fibrillation		OFFSIDES
85	Ventricular hypoplasia		OFFSIDES
86	Yawning		OFFSIDES
87	jaundice	11669021	CTD

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