Colesevelam Hydrochloride
(VTAKZNRDSPNOAU-UHFFFAOYSA-M)
Structure
- SMILES
- ClCC1CO1.C=CCNCCCCCC[N+](C)(C)C.CCCCCCCCCCNCC=C.NCC=C.Cl.[Cl-]
- Molecular Formula:
- C31H67Cl3N4O
- Molecular Weight:
- 618.249
- Log P:
- 5.9745
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 4
- TPSA:
- 62.61
- CAS Number(s):
- N/A
Synonym(s)
1.
Colesevelam Hydrochloride
2.
CholestaGel
3.
Colesevelam
4.
Colesevelam HCl
5.
GT 31104
6.
GT-31104
7.
GT31-104
8.
Welchol
9.
31104, GT
10.
GT31 104
11.
GT31104
12.
HCl, Colesevelam
13.
Hydrochloride, Colesevelam
External Link(s)
| MeSH | D000069472 |
| PubChem Compound | 160051 60208760 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | No adverse event | FAERS: 649 | US FAERS | |
| 2 | Constipation | FAERS: 144 | SIDER US FAERS | |
| 3 | Incorrect dose administered | FAERS: 84 | US FAERS | |
| 4 | Drug administration error | FAERS: 75 | US FAERS | |
| 5 | Nausea | FAERS: 50 | SIDER US FAERS | |
| 6 | Abdominal discomfort | FAERS: 49 | US FAERS | |
| 7 | Myalgia | FAERS: 43 | SIDER US FAERS | |
| 8 | Headache | FAERS: 39 | SIDER US FAERS | |
| 9 | Vomiting | FAERS: 36 | SIDER US FAERS | |
| 10 | Dyspepsia | FAERS: 35 | SIDER US FAERS | |
| 11 | Dizziness | FAERS: 31 | US FAERS | |
| 12 | Drug ineffective | FAERS: 27 | US FAERS | |
| 13 | Fatigue | FAERS: 27 | SIDER US FAERS | |
| 14 | Flatulence | FAERS: 26 | SIDER US FAERS | |
| 15 | Malaise | FAERS: 24 | US FAERS | |
| 16 | Arthralgia | FAERS: 22 | US FAERS | |
| 17 | Blood cholesterol increased | FAERS: 22 | US FAERS | |
| 18 | Back Pain | FAERS: 21 | SIDER US FAERS | |
| 19 | Blood triglycerides increased | FAERS: 20 | SIDER US FAERS | |
| 20 | Asthenia | FAERS: 19 | SIDER US FAERS | |
| 21 | Feeling abnormal | FAERS: 19 | US FAERS | |
| 22 | Unevaluable event | FAERS: 18 | US FAERS | |
| 23 | Pain | FAERS: 17 | SIDER US FAERS | |
| 24 | Pancreatitis | FAERS: 17 | SIDER US FAERS | |
| 25 | Weight decreased | FAERS: 17 | US FAERS | |
| 26 | Drug dose omission | FAERS: 16 | US FAERS | |
| 27 | Abdominal Pain | FAERS: 15 | SIDER US FAERS | |
| 28 | Blood glucose decreased | FAERS: 14 | US FAERS | |
| 29 | Pruritus | FAERS: 13 | US FAERS | |
| 30 | Therapeutic response unexpected | FAERS: 11 | US FAERS | |
| 31 | Blood glucose increased | FAERS: 10 | US FAERS | |
| 32 | Choking | FAERS: 10 | US FAERS | |
| 33 | Oropharyngeal pain | FAERS: 10 | US FAERS | |
| 34 | Cerebrovascular accident | FAERS: 9 | US FAERS | |
| 35 | Intestinal Obstruction | FAERS: 9 | SIDER US FAERS | |
| 36 | Product dose omission | FAERS: 9 | US FAERS | |
| 37 | Diabetes Mellitus | FAERS: 8 | SIDER US FAERS | |
| 38 | Hypersensitivity | FAERS: 8 | SIDER US FAERS | |
| 39 | Neck Pain | FAERS: 8 | US FAERS | |
| 40 | Peripheral swelling | FAERS: 8 | US FAERS | |
| 41 | Urticaria | FAERS: 8 | US FAERS | |
| 42 | Chest Pain | FAERS: 7 | US FAERS | |
| 43 | Drug prescribing error | FAERS: 7 | US FAERS | |
| 44 | Foreign body trauma | FAERS: 7 | US FAERS | |
| 45 | Myocardial Infarction | FAERS: 7 | SIDER US FAERS | |
| 46 | Pneumonia | FAERS: 7 | US FAERS | |
| 47 | Blood creatine phosphokinase increased | FAERS: 6 | US FAERS | |
| 48 | Bone pain | FAERS: 6 | US FAERS | |
| 49 | Tremor | FAERS: 6 | US FAERS | |
| 50 | Nasopharyngitis | FAERS: 5 | SIDER US FAERS | |
| 51 | Somnolence | FAERS: 5 | US FAERS | |
| 52 | Alopecia | FAERS: 4 | US FAERS | |
| 53 | Amnesia | FAERS: 4 | US FAERS | |
| 54 | Eructation | FAERS: 4 | US FAERS | |
| 55 | Gastrointestinal Pain | FAERS: 4 | SIDER US FAERS | |
| 56 | Medication residue present | FAERS: 4 | US FAERS | |
| 57 | Memory impairment | FAERS: 4 | US FAERS | |
| 58 | Musculoskeletal Pain | FAERS: 4 | US FAERS | |
| 59 | Palpitations | FAERS: 4 | US FAERS | |
| 60 | Retching | FAERS: 4 | US FAERS | |
| 61 | Swelling | FAERS: 4 | US FAERS | |
| 62 | Syncope | FAERS: 4 | US FAERS | |
| 63 | Throat irritation | FAERS: 4 | US FAERS | |
| 64 | Visual Impairment | FAERS: 4 | US FAERS | |
| 65 | Activities of daily living impaired | FAERS: 3 | US FAERS | |
| 66 | Adverse event | FAERS: 3 | US FAERS | |
| 67 | Arthropathy | FAERS: 3 | US FAERS | |
| 68 | Bronchitis | FAERS: 3 | US FAERS | |
| 69 | Chills | FAERS: 3 | US FAERS | |
| 70 | Colitis | FAERS: 3 | US FAERS | |
| 71 | Dehydration | FAERS: 3 | US FAERS | |
| 72 | Discomfort | FAERS: 3 | US FAERS | |
| 73 | Dysuria | FAERS: 3 | US FAERS | |
| 74 | Gastrointestinal motility disorder | FAERS: 3 | US FAERS | |
| 75 | Impaired gastric emptying | FAERS: 3 | US FAERS | |
| 76 | Influenza | FAERS: 3 | SIDER US FAERS | |
| 77 | Joint swelling | FAERS: 3 | US FAERS | |
| 78 | Laryngitis | FAERS: 3 | US FAERS | |
| 79 | Low density lipoprotein increased | FAERS: 3 | US FAERS | |
| 80 | Musculoskeletal stiffness | FAERS: 3 | US FAERS | |
| 81 | Product solubility abnormal | FAERS: 3 | US FAERS | |
| 82 | Sluggishness | FAERS: 3 | US FAERS | |
| 83 | Wrong technique in drug usage process | FAERS: 3 | US FAERS | |
| 84 | muscle injury | FAERS: 3 | US FAERS | |
| 85 | Abasia | FAERS: 2 | US FAERS | |
| 86 | Acne | FAERS: 2 | US FAERS | |
| 87 | Ageusia | FAERS: 2 | US FAERS | |
| 88 | Alanine Aminotransferase Increased | FAERS: 2 | US FAERS | |
| 89 | Anxiety | FAERS: 2 | US FAERS | |
| 90 | Atrial Fibrillation | FAERS: 2 | US FAERS | |
| 91 | Blindness | FAERS: 2 | US FAERS | |
| 92 | Blood glucose abnormal | FAERS: 2 | US FAERS | |
| 93 | Blood thyroid stimulating hormone increased | FAERS: 2 | US FAERS | |
| 94 | Blood triglycerides decreased | FAERS: 2 | US FAERS | |
| 95 | Cataract operation | FAERS: 2 | US FAERS | |
| 96 | Chest discomfort | FAERS: 2 | US FAERS | |
| 97 | Cholelithiasis | FAERS: 2 | US FAERS | |
| 98 | Diverticulitis | FAERS: 2 | US FAERS | |
| 99 | Diverticulum | FAERS: 2 | US FAERS | |
| 100 | Erythema | FAERS: 2 | US FAERS | |
| 101 | Fibromyalgia | FAERS: 2 | US FAERS | |
| 102 | Food craving | FAERS: 2 | US FAERS | |
| 103 | Glaucoma | FAERS: 2 | US FAERS | |
| 104 | Gout | FAERS: 2 | US FAERS | |
| 105 | High density lipoprotein increased | FAERS: 2 | US FAERS | |
| 106 | Infection | FAERS: 2 | SIDER US FAERS | |
| 107 | Irritable Bowel Syndrome | FAERS: 2 | US FAERS | |
| 108 | Limb discomfort | FAERS: 2 | US FAERS | |
| 109 | Lip swelling | FAERS: 2 | US FAERS | |
| 110 | Malabsorption | FAERS: 2 | US FAERS | |
| 111 | Medication Error | FAERS: 2 | US FAERS | |
| 112 | Middle insomnia | FAERS: 2 | US FAERS | |
| 113 | Myositis | FAERS: 2 | US FAERS | |
| 114 | Oral pain | FAERS: 2 | US FAERS | |
| 115 | Overdose | FAERS: 2 | US FAERS | |
| 116 | Pancreatic carcinoma | FAERS: 2 | US FAERS | |
| 117 | Paraparesis | FAERS: 2 | US FAERS | |
| 118 | Prescribed overdose | FAERS: 2 | US FAERS | |
| 119 | Product substitution issue | FAERS: 2 | US FAERS | |
| 120 | Regurgitation | FAERS: 2 | US FAERS | |
| 121 | Respiratory arrest | FAERS: 2 | US FAERS | |
| 122 | Rhabdomyolysis | FAERS: 2 | US FAERS | |
| 123 | Rhinitis | FAERS: 2 | SIDER US FAERS | |
| 124 | Sepsis | FAERS: 2 | US FAERS | |
| 125 | Sinusitis | FAERS: 2 | SIDER US FAERS | |
| 126 | Tablet issue | FAERS: 2 | US FAERS | |
| 127 | Thirst | FAERS: 2 | US FAERS | |
| 128 | Thoracotomy | FAERS: 2 | US FAERS | |
| 129 | Tinnitus | FAERS: 2 | US FAERS | |
| 130 | Ulcer | FAERS: 2 | US FAERS | |
| 131 | Vertigo | FAERS: 2 | US FAERS | |
| 132 | Anaphylactic shock | FAERS: 1 | US FAERS | |
| 133 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 134 | Ankle Fracture | FAERS: 1 | US FAERS | |
| 135 | Apathy | FAERS: 1 | US FAERS | |
| 136 | Aphagia | FAERS: 1 | US FAERS | |
| 137 | Appendicitis | FAERS: 1 | US FAERS | |
| 138 | Arthritis | FAERS: 1 | US FAERS | |
| 139 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 140 | Blood cholesterol abnormal | FAERS: 1 | US FAERS | |
| 141 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 142 | Blood glucose fluctuation | FAERS: 1 | US FAERS | |
| 143 | Blood magnesium decreased | FAERS: 1 | US FAERS | |
| 144 | Blood potassium increased | FAERS: 1 | US FAERS | |
| 145 | Blood pressure fluctuation | FAERS: 1 | US FAERS | |
| 146 | Bowel movement irregularity | FAERS: 1 | US FAERS | |
| 147 | Bradycardia | FAERS: 1 | SIDER US FAERS | |
| 148 | Burning sensation | FAERS: 1 | US FAERS | |
| 149 | Cholecystitis | FAERS: 1 | US FAERS | |
| 150 | Chromaturia | FAERS: 1 | US FAERS | |
| 151 | Cold sweat | FAERS: 1 | US FAERS | |
| 152 | Compression fracture | FAERS: 1 | US FAERS | |
| 153 | Deficiency of bile secretion | FAERS: 1 | US FAERS | |
| 154 | Dementia | FAERS: 1 | US FAERS | |
| 155 | Depressed mood | FAERS: 1 | US FAERS | |
| 156 | Diabetic Foot | FAERS: 1 | US FAERS | |
| 157 | Disability | FAERS: 1 | US FAERS | |
| 158 | Disorientation | FAERS: 1 | US FAERS | |
| 159 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 160 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 161 | Dry skin | FAERS: 1 | US FAERS | |
| 162 | Duodenitis | FAERS: 1 | US FAERS | |
| 163 | Dysgeusia | FAERS: 1 | US FAERS | |
| 164 | Dysphonia | FAERS: 1 | US FAERS | |
| 165 | Dysplasia | FAERS: 1 | US FAERS | |
| 166 | Ear congestion | FAERS: 1 | US FAERS | |
| 167 | Economic problem | FAERS: 1 | US FAERS | |
| 168 | Epistaxis | FAERS: 1 | US FAERS | |
| 169 | Erectile dysfunction | FAERS: 1 | US FAERS | |
| 170 | Escherichia infection | FAERS: 1 | US FAERS | |
| 171 | Expired product administered | FAERS: 1 | US FAERS | |
| 172 | Extra dose administered | FAERS: 1 | US FAERS | |
| 173 | Eye irritation | FAERS: 1 | US FAERS | |
| 174 | Feeling jittery | FAERS: 1 | US FAERS | |
| 175 | Flushing | FAERS: 1 | US FAERS | |
| 176 | Fracture | FAERS: 1 | US FAERS | |
| 177 | Gastric ulcer | FAERS: 1 | US FAERS | |
| 178 | Gastritis | FAERS: 1 | US FAERS | |
| 179 | Gastrointestinal inflammation | FAERS: 1 | US FAERS | |
| 180 | Gastrointestinal sounds abnormal | FAERS: 1 | US FAERS | |
| 181 | Gastrointestinal ulcer | FAERS: 1 | US FAERS | |
| 182 | General physical condition abnormal | FAERS: 1 | US FAERS | |
| 183 | Head discomfort | FAERS: 1 | US FAERS | |
| 184 | Hearing aid user | FAERS: 1 | US FAERS | |
| 185 | Hepatitis C | FAERS: 1 | US FAERS | |
| 186 | Hernia | FAERS: 1 | US FAERS | |
| 187 | Hunger | FAERS: 1 | US FAERS | |
| 188 | Hyperoxalaemia | FAERS: 1 | US FAERS | |
| 189 | Hypersomnia | FAERS: 1 | US FAERS | |
| 190 | Hypokinesia | FAERS: 1 | US FAERS | |
| 191 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 192 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 193 | Incorrect product administration duration | FAERS: 1 | US FAERS | |
| 194 | Inhibitory drug interaction | FAERS: 1 | US FAERS | |
| 195 | Intracranial Aneurysm | FAERS: 1 | US FAERS | |
| 196 | Joint Range of Motion Decreased | FAERS: 1 | US FAERS | |
| 197 | Joint stiffness | FAERS: 1 | US FAERS | |
| 198 | Lethargy | FAERS: 1 | US FAERS | |
| 199 | Limb injury | FAERS: 1 | US FAERS | |
| 200 | Limb operation | FAERS: 1 | US FAERS | |
| 201 | Low density lipoprotein abnormal | FAERS: 1 | US FAERS | |
| 202 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 203 | Macular degeneration | FAERS: 1 | US FAERS | |
| 204 | Metabolic acidosis | FAERS: 1 | US FAERS | |
| 205 | Migraine with Aura | FAERS: 1 | US FAERS | |
| 206 | Multiple Sclerosis | FAERS: 1 | US FAERS | |
| 207 | Muscle tightness | FAERS: 1 | US FAERS | |
| 208 | Nasal discomfort | FAERS: 1 | US FAERS | |
| 209 | Nasal mucosal disorder | FAERS: 1 | US FAERS | |
| 210 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 211 | Neuroma | FAERS: 1 | US FAERS | |
| 212 | Night sweats | FAERS: 1 | US FAERS | |
| 213 | Nocturia | FAERS: 1 | US FAERS | |
| 214 | Noninfective gingivitis | FAERS: 1 | US FAERS | |
| 215 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 216 | Osteoporosis | FAERS: 1 | US FAERS | |
| 217 | Oxalosis | FAERS: 1 | US FAERS | |
| 218 | Oxygen supplementation | FAERS: 1 | US FAERS | |
| 219 | Pancreatic infarction | FAERS: 1 | US FAERS | |
| 220 | Paranasal sinus hypersecretion | FAERS: 1 | US FAERS | |
| 221 | Paresis | FAERS: 1 | US FAERS | |
| 222 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 223 | Product administration error | FAERS: 1 | US FAERS | |
| 224 | Product coating issue | FAERS: 1 | US FAERS | |
| 225 | Product quality issue | FAERS: 1 | US FAERS | |
| 226 | Product residue present | FAERS: 1 | US FAERS | |
| 227 | Product size issue | FAERS: 1 | US FAERS | |
| 228 | Product taste abnormal | FAERS: 1 | US FAERS | |
| 229 | Pseudocyst | FAERS: 1 | US FAERS | |
| 230 | Quality of life decreased | FAERS: 1 | US FAERS | |
| 231 | Rectal tenesmus | FAERS: 1 | US FAERS | |
| 232 | Renal cyst | FAERS: 1 | US FAERS | |
| 233 | Respiratory distress | FAERS: 1 | US FAERS | |
| 234 | Restless Legs Syndrome | FAERS: 1 | US FAERS | |
| 235 | Restlessness | FAERS: 1 | US FAERS | |
| 236 | Sick relative | FAERS: 1 | US FAERS | |
| 237 | Skeletal injury | FAERS: 1 | US FAERS | |
| 238 | Sphincter of Oddi Dysfunction | FAERS: 1 | US FAERS | |
| 239 | Stomatitis | FAERS: 1 | US FAERS | |
| 240 | Stool analysis abnormal | FAERS: 1 | US FAERS | |
| 241 | Sudden onset of sleep | FAERS: 1 | US FAERS | |
| 242 | Throat cancer | FAERS: 1 | US FAERS | |
| 243 | Thrombosis | FAERS: 1 | US FAERS | |
| 244 | Thyroid Neoplasm | FAERS: 1 | US FAERS | |
| 245 | Tongue blistering | FAERS: 1 | US FAERS | |
| 246 | Tooth Infection | FAERS: 1 | US FAERS | |
| 247 | Transplant | FAERS: 1 | US FAERS | |
| 248 | Umbilical hernia | FAERS: 1 | US FAERS | |
| 249 | Upper airway obstruction | FAERS: 1 | US FAERS | |
| 250 | Viral upper respiratory tract infection | FAERS: 1 | US FAERS | |
| 251 | Vulvovaginal pruritus | FAERS: 1 | US FAERS | |
| 252 | cancer surgery | FAERS: 1 | US FAERS | |
| 253 | nervous system disorder | FAERS: 1 | SIDER US FAERS | |
| 254 | Acute Coronary Syndrome | SIDER | ||
| 255 | Aortic Valve Stenosis | SIDER | ||
| 256 | Dermatitis | SIDER | ||
| 257 | Diabetic | SIDER | ||
| 258 | Musculoskeletal discomfort | SIDER | ||
| 259 | Pharyngitis | SIDER | ||
| 260 | Serum triglycerides increased | SIDER | ||
| 261 | Transaminases increased | SIDER |
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