abacavir, lamivudine drug combination
(UGWQMIXVUBLMAH-IVVFTGHFSA-N)
Structure
- SMILES
- Nc1ccn(c(=O)n1)[C@@H]1CS[C@@H](O1)CO.OC[C@@H]1C=C[C@@H](C1)n1cnc2c1nc(N)nc2NC1CC1
- Molecular Formula:
- C22H29N9O4S
- Molecular Weight:
- 515.589
- Log P:
- 1.7336
- Hydrogen Bond Acceptor:
- 14
- Hydrogen Bond Donor:
- 5
- TPSA:
- 217.55
- CAS Number(s):
- 852337-16-7
Synonym(s)
1.
abacavir, lamivudine drug combination
2.
Epzicom
3.
abacavir - lamivudine
4.
abacavir sulfate-lamivudine combination
5.
abacavir-lamivudine combination
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Myocardial Infarction | FAERS: 29 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 2 | Hypersensitivity | FAERS: 10 | US FAERS | |
| 3 | Cerebrovascular accident | FAERS: 7 | US FAERS | |
| 4 | Thrombocytopenia | FAERS: 6 | US FAERS | |
| 5 | Pruritus | FAERS: 5 | US FAERS | |
| 6 | Vomiting | FAERS: 5 | US FAERS | |
| 7 | Angina Pectoris | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 8 | Asthenia | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Chest Pain | FAERS: 4 | US FAERS | |
| 10 | Malaise | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 11 | Nausea | FAERS: 4 | US FAERS | |
| 12 | Abdominal Pain | FAERS: 3 | US FAERS | |
| 13 | Arthralgia | FAERS: 3 | US FAERS | |
| 14 | Drug ineffective | FAERS: 3 | US FAERS | |
| 15 | Fatigue | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Myalgia | FAERS: 3 | US FAERS | |
| 17 | Palpitations | FAERS: 3 | US FAERS | |
| 18 | Tablet physical issue | FAERS: 3 | US FAERS | |
| 19 | Urticaria | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 20 | Weight decreased | FAERS: 3 | US FAERS | |
| 21 | Cell Death | FAERS: 2 | US FAERS | |
| 22 | Chest discomfort | FAERS: 2 | US FAERS | |
| 23 | Chills | FAERS: 2 | US FAERS | |
| 24 | Cholestasis | FAERS: 2 | US FAERS | |
| 25 | Dizziness | FAERS: 2 | US FAERS | |
| 26 | Erythema | FAERS: 2 | US FAERS | |
| 27 | Leukopenia | FAERS: 2 | US FAERS | |
| 28 | Lymphopenia | FAERS: 2 | US FAERS | |
| 29 | Neutrophil count decreased | FAERS: 2 | US FAERS | |
| 30 | Overdose | FAERS: 2 | US FAERS | |
| 31 | Papule | FAERS: 2 | US FAERS | |
| 32 | Product quality issue | FAERS: 2 | US FAERS | |
| 33 | Stevens-Johnson Syndrome | FAERS: 2 | US FAERS | |
| 34 | Sudden death | FAERS: 2 | US FAERS | |
| 35 | Thrombocytopenic purpura | FAERS: 2 | US FAERS | |
| 36 | Acne | FAERS: 1 | US FAERS | |
| 37 | Acute myocardial infarction | FAERS: 1 | US FAERS | |
| 38 | Adverse event | FAERS: 1 | US FAERS | |
| 39 | Blood iron decreased | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 40 | Blood phosphorus increased | FAERS: 1 | US FAERS | |
| 41 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 42 | Cardiac Tamponade | FAERS: 1 | US FAERS | |
| 43 | Cardiotoxicity | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 44 | Dysuria | FAERS: 1 | US FAERS | |
| 45 | Eosinophilic Pneumonia | FAERS: 1 | US FAERS | |
| 46 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 47 | Gamma-Glutamyltransferase Increased | FAERS: 1 | US FAERS | |
| 48 | Head discomfort | FAERS: 1 | US FAERS | |
| 49 | Headache | FAERS: 1 | US FAERS | |
| 50 | Hepatomegaly | FAERS: 1 | US FAERS | |
| 51 | Hepatotoxicity | FAERS: 1 | US FAERS | |
| 52 | Infection | FAERS: 1 | US FAERS | |
| 53 | Inflammation | FAERS: 1 | US FAERS | |
| 54 | Lip swelling | FAERS: 1 | US FAERS | |
| 55 | Macrocytosis | FAERS: 1 | US FAERS | |
| 56 | Mental impairment | FAERS: 1 | US FAERS | |
| 57 | Myelitis | FAERS: 1 | US FAERS | |
| 58 | Myelofibrosis | FAERS: 1 | US FAERS | |
| 59 | Nuchal Rigidity | FAERS: 1 | US FAERS | |
| 60 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 61 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 62 | Pain | FAERS: 1 | US FAERS | |
| 63 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 64 | Pneumonia | FAERS: 1 | US FAERS | |
| 65 | Post procedural stroke | FAERS: 1 | US FAERS | |
| 66 | Respiratory distress | FAERS: 1 | US FAERS | |
| 67 | Rhinitis | FAERS: 1 | US FAERS | |
| 68 | Skin lesion | FAERS: 1 | US FAERS | |
| 69 | Suicide attempt | FAERS: 1 | US FAERS | |
| 70 | Transaminases increased | FAERS: 1 | US FAERS | |
| 71 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 72 | jaundice | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 73 | Anemia | 14986271 | CTD | |
| 74 | HIV Infections | 19542866 20204580 | CTD |
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