tezosentan
(TUYWTLTWNJOZNY-UHFFFAOYSA-N)
Structure
- SMILES
- OCCOc1nc(nc(c1Oc1ccccc1OC)NS(=O)(=O)c1ccc(cn1)C(C)C)c1ccnc(c1)c1nn[nH]n1
- Type(s)
- Investigational
- Molecular Formula:
- C27H27N9O6S
- Molecular Weight:
- 605.625
- Log P:
- 4.3637
- Hydrogen Bond Acceptor:
- 14
- Hydrogen Bond Donor:
- 3
- TPSA:
- 208.49
- CAS Number(s):
- 180384-57-0
Synonym(s)
1.
tezosentan
2.
5-isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-1H-tetrazol-5-yl--pyridin-4-yl)--pyrimidin-4-ylamide
3.
RO 61-0612
4.
RO 610612
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Acute Lung Injury | 16625121 | CTD | |
| 2 | Heart Diseases | 16219361 | CTD | |
| 3 | Heart failure | 16181825 | CTD | |
| 4 | Hepatorenal Syndrome | 16219361 | CTD | |
| 5 | Meconium Aspiration Syndrome | 16327003 | CTD | |
| 6 | Respiratory Distress Syndrome, Adult | 16625121 | CTD |
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