eslicarbazepine acetate
(QIALRBLEEWJACW-INIZCTEOSA-N)
Structure
- SMILES
- CC(=O)O[C@H]1Cc2ccccc2N(c2c1cccc2)C(=O)N
- Type(s)
- Approved
- Molecular Formula:
- C17H16N2O3
- Molecular Weight:
- 296.321
- Log P:
- 3.8290
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 1
- TPSA:
- 72.63
- CAS Number(s):
- 236395-14-5
Synonym(s)
1.
eslicarbazepine acetate
2.
10-acetoxy-10,11-dihydro-5H-dibenz(b,f)azepine-5-carboxamide
3.
Aptiom
4.
BIA 2-093
5.
BIA-2-093
6.
Zebinix
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 31 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Dizziness | FAERS: 26 | US FAERS | |
| 3 | Feeling abnormal | FAERS: 16 | US FAERS | |
| 4 | Somnolence | FAERS: 16 | US FAERS | |
| 5 | Headache | FAERS: 15 | US FAERS | |
| 6 | Nausea | FAERS: 11 | US FAERS | |
| 7 | Vomiting | FAERS: 11 | US FAERS | |
| 8 | Blood sodium decreased | FAERS: 10 | US FAERS | |
| 9 | Memory impairment | FAERS: 10 | US FAERS | |
| 10 | Pruritus | FAERS: 10 | US FAERS | |
| 11 | Drug dose omission | FAERS: 9 | US FAERS | |
| 12 | Malaise | FAERS: 9 | US FAERS | |
| 13 | Drug dose titration not performed | FAERS: 8 | US FAERS | |
| 14 | Fatigue | FAERS: 8 | US FAERS | |
| 15 | Overdose | FAERS: 7 | US FAERS | |
| 16 | Peripheral swelling | FAERS: 6 | US FAERS | |
| 17 | Product dose omission | FAERS: 6 | US FAERS | |
| 18 | Agitation | FAERS: 5 | US FAERS | |
| 19 | Asthenia | FAERS: 5 | US FAERS | |
| 20 | Product use in unapproved indication | FAERS: 5 | US FAERS | |
| 21 | Tremor | FAERS: 5 | US FAERS | |
| 22 | Vertigo | FAERS: 5 | US FAERS | |
| 23 | Anger | FAERS: 4 | US FAERS | |
| 24 | Aura | FAERS: 4 | US FAERS | |
| 25 | Drug ineffective for unapproved indication | FAERS: 4 | US FAERS | |
| 26 | Epilepsy | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 27 | Hypersensitivity | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 28 | Nervousness | FAERS: 4 | US FAERS | |
| 29 | Paranoia | FAERS: 4 | US FAERS | |
| 30 | Amnesia | FAERS: 3 | US FAERS | |
| 31 | Anxiety | FAERS: 3 | US FAERS | |
| 32 | Aphasia | FAERS: 3 | US FAERS | |
| 33 | Bradycardia | FAERS: 3 | US FAERS | |
| 34 | Bradyphrenia | FAERS: 3 | US FAERS | |
| 35 | Cerebrovascular accident | FAERS: 3 | US FAERS | |
| 36 | Chills | FAERS: 3 | US FAERS | |
| 37 | Erythema | FAERS: 3 | US FAERS | |
| 38 | Inappropriate schedule of drug administration | FAERS: 3 | US FAERS | |
| 39 | Inappropriate schedule of product administration | FAERS: 3 | US FAERS | |
| 40 | Lethargy | FAERS: 3 | US FAERS | |
| 41 | Lip swelling | FAERS: 3 | US FAERS | |
| 42 | Mood swings | FAERS: 3 | US FAERS | |
| 43 | Myalgia | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 44 | Pain | FAERS: 3 | US FAERS | |
| 45 | Stevens-Johnson Syndrome | FAERS: 3 | US FAERS | |
| 46 | Visual Impairment | FAERS: 3 | US FAERS | |
| 47 | Weight decreased | FAERS: 3 | US FAERS | |
| 48 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 49 | Adams-Stokes Syndrome | FAERS: 2 | US FAERS | |
| 50 | Angioedema | FAERS: 2 | US FAERS | |
| 51 | Asthma | FAERS: 2 | US FAERS | |
| 52 | Ataxia | FAERS: 2 | US FAERS | |
| 53 | Cerebral disorder | FAERS: 2 | US FAERS | |
| 54 | Constipation | FAERS: 2 | US FAERS | |
| 55 | Dementia | FAERS: 2 | US FAERS | |
| 56 | Diplopia | FAERS: 2 | US FAERS | |
| 57 | Disorientation | FAERS: 2 | US FAERS | |
| 58 | Drug administration error | FAERS: 2 | US FAERS | |
| 59 | Drug screen false positive | FAERS: 2 | US FAERS | |
| 60 | Dysphemia | FAERS: 2 | US FAERS | |
| 61 | Epistaxis | FAERS: 2 | US FAERS | |
| 62 | Erythema Multiforme | FAERS: 2 | US FAERS | |
| 63 | Flushing | FAERS: 2 | US FAERS | |
| 64 | Gait inability | FAERS: 2 | US FAERS | |
| 65 | Hypersomnia | FAERS: 2 | US FAERS | |
| 66 | Lymphadenopathy | FAERS: 2 | US FAERS | |
| 67 | Myoclonic Epilepsy | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 68 | Myoclonus | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 69 | Nephrolithiasis | FAERS: 2 | US FAERS | |
| 70 | Pain of skin | FAERS: 2 | US FAERS | |
| 71 | Product use issue | FAERS: 2 | US FAERS | |
| 72 | Respiratory tract congestion | FAERS: 2 | US FAERS | |
| 73 | Status Epilepticus | FAERS: 2 | US FAERS | |
| 74 | Stress | FAERS: 2 | US FAERS | |
| 75 | Swelling | FAERS: 2 | US FAERS | |
| 76 | Therapeutic response unexpected | FAERS: 2 | US FAERS | |
| 77 | Thrombocytopenia | FAERS: 2 | US FAERS | |
| 78 | Trigeminal Neuralgia | FAERS: 2 | US FAERS | |
| 79 | Urinary Incontinence | FAERS: 2 | US FAERS | |
| 80 | Urinary tract infection | FAERS: 2 | US FAERS | |
| 81 | Urticaria | FAERS: 2 | US FAERS | |
| 82 | Wheezing | FAERS: 2 | US FAERS | |
| 83 | Abasia | FAERS: 1 | US FAERS | |
| 84 | Acne | FAERS: 1 | US FAERS | |
| 85 | Agranulocytosis | FAERS: 1 | US FAERS | |
| 86 | Alcohol withdrawal syndrome | FAERS: 1 | US FAERS | |
| 87 | Alopecia | FAERS: 1 | US FAERS | |
| 88 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 89 | Ammonia increased | FAERS: 1 | US FAERS | |
| 90 | Ankle Fracture | FAERS: 1 | US FAERS | |
| 91 | Anticonvulsant drug level increased | FAERS: 1 | US FAERS | |
| 92 | Arthralgia | FAERS: 1 | US FAERS | |
| 93 | Atrioventricular Block | FAERS: 1 | US FAERS | |
| 94 | Blepharospasm | FAERS: 1 | US FAERS | |
| 95 | Blood glucose increased | FAERS: 1 | US FAERS | |
| 96 | Blood potassium increased | FAERS: 1 | US FAERS | |
| 97 | Bronchitis | FAERS: 1 | US FAERS | |
| 98 | Bronchospasm | FAERS: 1 | US FAERS | |
| 99 | Burning sensation | FAERS: 1 | US FAERS | |
| 100 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 101 | Cardiac Death | FAERS: 1 | US FAERS | |
| 102 | Cell Death | FAERS: 1 | US FAERS | |
| 103 | Change in seizure presentation | FAERS: 1 | US FAERS | |
| 104 | Chest Pain | FAERS: 1 | US FAERS | |
| 105 | Chest discomfort | FAERS: 1 | US FAERS | |
| 106 | Cholestasis | FAERS: 1 | US FAERS | |
| 107 | Clumsiness | FAERS: 1 | US FAERS | |
| 108 | Cold sweat | FAERS: 1 | US FAERS | |
| 109 | Completed Suicide | FAERS: 1 | US FAERS | |
| 110 | Crying | FAERS: 1 | US FAERS | |
| 111 | Deep Vein Thrombosis | FAERS: 1 | US FAERS | |
| 112 | Depressed Level of Consciousness | FAERS: 1 | US FAERS | |
| 113 | Depressed mood | FAERS: 1 | US FAERS | |
| 114 | Diabetes Mellitus | FAERS: 1 | US FAERS | |
| 115 | Discomfort | FAERS: 1 | US FAERS | |
| 116 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 117 | Dysarthria | FAERS: 1 | US FAERS | |
| 118 | Dysgeusia | FAERS: 1 | US FAERS | |
| 119 | Dysuria | FAERS: 1 | US FAERS | |
| 120 | Emotional disorder | FAERS: 1 | US FAERS | |
| 121 | Enuresis | FAERS: 1 | US FAERS | |
| 122 | Eosinophilia | FAERS: 1 | US FAERS | |
| 123 | Epileptic aura | FAERS: 1 | US FAERS | |
| 124 | Expired product administered | FAERS: 1 | US FAERS | |
| 125 | Eye Infection | FAERS: 1 | US FAERS | |
| 126 | Eye inflammation | FAERS: 1 | US FAERS | |
| 127 | Eye pain | FAERS: 1 | US FAERS | |
| 128 | Facial Pain | FAERS: 1 | US FAERS | |
| 129 | Feeling Cold | FAERS: 1 | US FAERS | |
| 130 | Flat affect | FAERS: 1 | US FAERS | |
| 131 | Focal dyscognitive seizures | FAERS: 1 | US FAERS | |
| 132 | Full blood count decreased | FAERS: 1 | US FAERS | |
| 133 | Gamma-Glutamyltransferase Increased | FAERS: 1 | US FAERS | |
| 134 | Hand-eye coordination impaired | FAERS: 1 | US FAERS | |
| 135 | Hepatitis | FAERS: 1 | US FAERS | |
| 136 | Hunger | FAERS: 1 | US FAERS | |
| 137 | Hyperphagia | FAERS: 1 | US FAERS | |
| 138 | Hypokinesia | FAERS: 1 | US FAERS | |
| 139 | Hyponatraemic seizure | FAERS: 1 | US FAERS | |
| 140 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 141 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 142 | Infection | FAERS: 1 | US FAERS | |
| 143 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 144 | Intercepted drug administration error | FAERS: 1 | US FAERS | |
| 145 | Laceration | FAERS: 1 | US FAERS | |
| 146 | Lennox-Gastaut syndrome | FAERS: 1 | US FAERS | |
| 147 | Lymphopenia | FAERS: 1 | US FAERS | |
| 148 | Metamorphopsia | FAERS: 1 | US FAERS | |
| 149 | Mineral deficiency | FAERS: 1 | US FAERS | |
| 150 | Multimorbidity | FAERS: 1 | US FAERS | |
| 151 | Nephrotic Syndrome | FAERS: 1 | US FAERS | |
| 152 | Neutropenia | FAERS: 1 | US FAERS | |
| 153 | Palpitations | FAERS: 1 | US FAERS | |
| 154 | Pancreatitis | FAERS: 1 | US FAERS | |
| 155 | Pancytopenia | FAERS: 1 | US FAERS | |
| 156 | Petechiae | FAERS: 1 | US FAERS | |
| 157 | Photophobia | FAERS: 1 | US FAERS | |
| 158 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 159 | Postictal psychosis | FAERS: 1 | US FAERS | |
| 160 | Pregnancy | FAERS: 1 | US FAERS | |
| 161 | Product administered to patient of inappropriate age | FAERS: 1 | US FAERS | |
| 162 | Product use complaint | FAERS: 1 | US FAERS | |
| 163 | Pseudomononucleosis | FAERS: 1 | US FAERS | |
| 164 | Serotonin Syndrome | FAERS: 1 | US FAERS | |
| 165 | Simple Partial Seizures | FAERS: 1 | US FAERS | |
| 166 | Sinus bradycardia | FAERS: 1 | US FAERS | |
| 167 | Skin irritation | FAERS: 1 | US FAERS | |
| 168 | Slow speech | FAERS: 1 | US FAERS | |
| 169 | Staring | FAERS: 1 | US FAERS | |
| 170 | Sudden death | FAERS: 1 | US FAERS | |
| 171 | Syncope | FAERS: 1 | US FAERS | |
| 172 | Tachycardia | FAERS: 1 | US FAERS | |
| 173 | Tension Headache | FAERS: 1 | US FAERS | |
| 174 | Tension | FAERS: 1 | US FAERS | |
| 175 | Throat irritation | FAERS: 1 | US FAERS | |
| 176 | Tinnitus | FAERS: 1 | US FAERS | |
| 177 | Toxic Epidermal Necrolysis | FAERS: 1 | US FAERS | |
| 178 | Tuberculosis | FAERS: 1 | US FAERS | |
| 179 | Urinary Retention | FAERS: 1 | US FAERS | |
| 180 | Wrong dose | FAERS: 1 | US FAERS | |
| 181 | Wrong schedule | FAERS: 1 | US FAERS | |
| 182 | Wrong technique in product usage process | FAERS: 1 | US FAERS | |
| 183 | Seizures | 16920333 | CTD |
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