MetaADEDB 2.0 @ LMMD
tranilast
(NZHGWWWHIYHZNX-CSKARUKUSA-N)
Structure
SMILES
COc1cc(/C=C/C(=O)Nc2ccccc2C(=O)O)ccc1OC
Type(s)
Investigational
Molecular Formula:
C18H17NO5
Molecular Weight:
327.331
Log P:
3.1269
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
84.86
CAS Number(s):
53902-12-8; 53902-17-3; 70806-55-2
Synonym(s)
1.
tranilast
2.
N-(3',4'-dimethoxycinnamoyl)anthranilic acid
3.
tranilast hydrate
4.
tranilast sodium salt
External Link(s)
MeSHC012293
PubChem Compound5282230
BindingDB21613
ChEBI92320
77572
CHEMBLCHEMBL415324
DrugBankDB07615
DrugCentral2714
IUPHAR/BPS Guide to PHARMACOLOGY6326
KEGGdr:D02027
Therapeutic Target DatabaseD00PVQ
D0E6OC
ZINC797
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Activities of daily living impairedOFFSIDES
2Alanine Aminotransferase IncreasedOFFSIDES
3Altered state of consciousnessOFFSIDES
4ApathyOFFSIDES
5ArteriosclerosisOFFSIDES
6AscitesOFFSIDES
7Asthma2434109CTD
OFFSIDES
8AtelectasisOFFSIDES
9Bilirubin conjugated increasedOFFSIDES
10Blood albumin decreasedOFFSIDES
11Blood alkaline phosphatase increasedOFFSIDES
12Blood creatinine increasedOFFSIDES
13Blood immunoglobulin G increasedOFFSIDES
14Blood lactate dehydrogenase increasedOFFSIDES
15Blood prolactin increasedOFFSIDES
16Blood urea increasedOFFSIDES
17BradycardiaOFFSIDES
18CholangiolitisOFFSIDES
19Corneal UlcerOFFSIDES
20DehydrationOFFSIDES
21Diabetic Autonomic NeuropathyOFFSIDES
22Drug exposure during pregnancyOFFSIDES
23DysuriaOFFSIDES
24ErythemaOFFSIDES
25Gamma-Glutamyltransferase IncreasedOFFSIDES
26Gingival HyperplasiaOFFSIDES
27GlobulinuriaOFFSIDES
28GoiterOFFSIDES
29HamartomaOFFSIDES
30Hepatic necrosisOFFSIDES
31HepatitisOFFSIDES
32Injection site erythemaOFFSIDES
33Kidney FailureOFFSIDES
34Lymphocyte count decreasedOFFSIDES
35NasopharyngitisOFFSIDES
36Neoplasm Invasiveness25826687CTD
37OliguriaOFFSIDES
38Pericardial effusionOFFSIDES
39Respiratory FailureOFFSIDES
40Trisomy 22OFFSIDES
41Upper respiratory tract inflammationOFFSIDES
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