MetaADEDB 2.0 @ LMMD
pranlukast
(NBQKINXMPLXUET-UHFFFAOYSA-N)
Structure
SMILES
O=C(c1ccc(cc1)OCCCCc1ccccc1)Nc1cccc2c1oc(cc2=O)c1nn[nH]n1
Type(s)
Investigational
ATC code(s)
R03DC02
Molecular Formula:
C27H23N5O4
Molecular Weight:
481.503
Log P:
4.7001
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
2
TPSA:
123
CAS Number(s):
103177-37-3; 150821-03-7
Synonym(s)
1.
pranlukast
2.
8-(4 (4-phenylbutoxy)benzoyl)amino-2-(tetrazol-5'-yl)-4-oxo-4H-1-benzopyran
3.
ONO 1078
4.
ONO-1078
5.
ONO-RS 411
6.
ONO-RS-411
7.
SB 205312
External Link(s)
MeSHC047681
PubChem Compound4887
BindingDB50023198
ChEBI94810
CHEMBLCHEMBL21333
DrugBankDB01411
DrugCentral2237
IUPHAR/BPS Guide to PHARMACOLOGY3634
KEGGdr:D08408
Therapeutic Target DatabaseD08QIP
ZINC1542146
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute bronchitisOFFSIDES
2Acute otitis mediaOFFSIDES
3Acute respiratory failureOFFSIDES
4AdenoidectomyOFFSIDES
5Airway Obstruction11256554
18430318		CTD
6Alanine Aminotransferase IncreasedOFFSIDES
7Altered state of consciousnessOFFSIDES
8Antinuclear antibody increasedOFFSIDES
9AsphyxiaOFFSIDES
10Asthma, Aspirin-Induced19667532CTD
11Asthma

View details

9071168
9303339
9513583
10069892
11393418
11527250
12153692
12360108
12489251
14584388
14650364
16270722
18430318
20332717
 		CTD
OFFSIDES
12Bacteria urine identifiedOFFSIDES
13BlepharoptosisOFFSIDES
14Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
15Blood albumin decreasedOFFSIDES
16Blood glucose decreasedOFFSIDES
17Blood immunoglobulin EOFFSIDES
18Blood lactate dehydrogenase decreasedOFFSIDES
19Blood lactate dehydrogenase increasedOFFSIDES
20Blood parathyroid hormone increasedOFFSIDES
21Blood potassium increasedOFFSIDES
22Blood triglycerides increasedOFFSIDES
23Blood urea increasedOFFSIDES
24Blood uric acidOFFSIDES
25Brain natriuretic peptide increasedOFFSIDES
26BronchopneumoniaOFFSIDES
27CheilitisOFFSIDES
28Chemical and Drug Induced Liver Injury23956101CTD
29Chemotherapeutic drug level increasedOFFSIDES
30CholecystitisOFFSIDES
31Cold sweatOFFSIDES
32CyanosisOFFSIDES
33Deafness NeurosensoryOFFSIDES
34DeafnessOFFSIDES
35Detachment of retinal pigment epitheliumOFFSIDES
36Diabetic NephropathyOFFSIDES
37Diffuse panbronchiolitisOFFSIDES
38DyslaliaOFFSIDES
39DysphoniaOFFSIDES
40Endotoxic shockOFFSIDES
41EnterocolitisOFFSIDES
42Eosinophilia11514498CTD
43Eosinophilic PneumoniaOFFSIDES
44EpilepsyOFFSIDES
45Erythema MultiformeOFFSIDES
46Eyelids pruritusOFFSIDES
47Fanconi SyndromeOFFSIDES
48Feeling ColdOFFSIDES
49GalactorrheaOFFSIDES
50GastroenteritisOFFSIDES
51GlaucomaOFFSIDES
52GlossoptosisOFFSIDES
53Heat illnessOFFSIDES
54HordeolumOFFSIDES
55Infected epidermal cystOFFSIDES
56Inflammation19129732CTD
57Intestinal Diseases18236018CTD
58Ischemia19129732CTD
59Leucine aminopeptidase increasedOFFSIDES
60Leukopenia neonatalOFFSIDES
61Lip erosionOFFSIDES
62Lung consolidationOFFSIDES
63Lymphocyte count decreasedOFFSIDES
64Mesenteric vascular insufficiencyOFFSIDES
65Myocarditis11514498CTD
66NasopharyngitisOFFSIDES
67Neisseria infectionOFFSIDES
68Neuroleptic Malignant SyndromeOFFSIDES
69Neutrophil count decreasedOFFSIDES
70Ocular icterusOFFSIDES
71Oropharyngeal discomfortOFFSIDES
72Pain of skinOFFSIDES
73Peritoneal DialysisOFFSIDES
74Pharyngolaryngeal discomfortOFFSIDES
75PhlebosclerosisOFFSIDES
76Pneumocystis jiroveci pneumoniaOFFSIDES
77Pneumonia21429049CTD
78Psychiatric symptomOFFSIDES
79Radial nerve palsyOFFSIDES
80Refusal of treatment by relativeOFFSIDES
81Rhinitis20332717CTD
82Shunt malfunctionOFFSIDES
83Sputum culture positiveOFFSIDES
84Status EpilepticusOFFSIDES
85Stevens-Johnson SyndromeOFFSIDES
86Sudden deathOFFSIDES
87Therapy non-responderOFFSIDES
88Therapy regimen changedOFFSIDES
89TonsillitisOFFSIDES
90TracheobronchitisOFFSIDES
91Upper respiratory tract inflammationOFFSIDES
92Vitamin K DeficiencyOFFSIDES
93Vocal Cord ParalysisOFFSIDES
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