amlodipine, perindopril drug combination
(MZISJGWEZUMGBB-DFFKMLNVSA-N)
Structure
- SMILES
- OS(=O)(=O)c1ccccc1.OC(=O)[C@H](CCCN=C(N)N)N.CCC[C@@H](C(=O)OCC)N[C@H](C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O)C.NCCOCC1=C(C(=O)OCC)C(C(=C(N1)C)C(=O)OC)c1ccccc1Cl
- Molecular Formula:
- C51H77ClN8O15S
- Molecular Weight:
- 1109.720
- Log P:
- 8.1317
- Hydrogen Bond Acceptor:
- 23
- Hydrogen Bond Donor:
- 9
- TPSA:
- 386.29
- CAS Number(s):
- 1265624-53-0
Synonym(s)
1.
amlodipine, perindopril drug combination
2.
amlodipine - perindopril
3.
coveram
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hypotension | FAERS: 4 | US FAERS | |
| 2 | Axonal neuropathy | FAERS: 3 | US FAERS | |
| 3 | Shock | FAERS: 3 | US FAERS | |
| 4 | Acute kidney injury | FAERS: 2 | US FAERS | |
| 5 | Angioedema | FAERS: 2 | US FAERS | |
| 6 | Bronchopneumopathy | FAERS: 2 | US FAERS | |
| 7 | Cholelithiasis | FAERS: 2 | US FAERS | |
| 8 | Fatigue | FAERS: 2 | US FAERS | |
| 9 | Myalgia | FAERS: 2 | US FAERS | |
| 10 | Splenic vein thrombosis | FAERS: 2 | US FAERS | |
| 11 | Systemic Inflammatory Response Syndrome | FAERS: 2 | US FAERS | |
| 12 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 13 | Accidental overdose | FAERS: 1 | US FAERS | |
| 14 | Asthenia | FAERS: 1 | US FAERS | |
| 15 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 16 | Chest Pain | FAERS: 1 | US FAERS | |
| 17 | Completed Suicide | FAERS: 1 | US FAERS | |
| 18 | Dental Restoration Failure | FAERS: 1 | US FAERS | |
| 19 | Dizziness | FAERS: 1 | US FAERS | |
| 20 | Gamma-Glutamyltransferase Increased | FAERS: 1 | US FAERS | |
| 21 | Headache | FAERS: 1 | US FAERS | |
| 22 | Malaise | FAERS: 1 | US FAERS | |
| 23 | Medication Error | FAERS: 1 | US FAERS | |
| 24 | Myoclonus | FAERS: 1 | US FAERS | |
| 25 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 26 | Ocular vasculitis | FAERS: 1 | US FAERS | |
| 27 | Onychoclasis | FAERS: 1 | US FAERS | |
| 28 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 29 | Product use issue | FAERS: 1 | US FAERS | |
| 30 | Pruritus | FAERS: 1 | US FAERS | |
| 31 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 32 | Tooth Erosion | FAERS: 1 | US FAERS | |
| 33 | Transaminases increased | FAERS: 1 | US FAERS | |
| 34 | Vitamin D Deficiency | FAERS: 1 | US FAERS | |
| 35 | Vomiting | FAERS: 1 | US FAERS |
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