MetaADEDB 2.0 @ LMMD
lamivudine, zidovudine drug combination
(LHCOVOKZWQYODM-CPEOKENHSA-N)
Structure
SMILES
Nc1ccn(c(=O)n1)[C@@H]1CS[C@@H](O1)CO.OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1cc(C)c(=O)[nH]c1=O
Molecular Formula:
C18H24N8O7S
Molecular Weight:
496.498
Log P:
-0.7564
Hydrogen Bond Acceptor:
13
Hydrogen Bond Donor:
4
TPSA:
249.74
CAS Number(s):
165456-81-5
Synonym(s)
1.
lamivudine, zidovudine drug combination
2.
Combivir
External Link(s)
MeSHC109078
PubChem Compound160352
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Bone marrow toxicityFAERS: 2US FAERS
2Lipodystrophy acquiredFAERS: 2US FAERS
3treatment failureFAERS: 2US FAERS
4Acute Coronary SyndromeFAERS: 1US FAERS
5Acute myocardial infarctionFAERS: 1US FAERS
6AnxietyFAERS: 1US FAERS
7AstheniaFAERS: 1US FAERS
8Body fat disorderFAERS: 1US FAERS
9CachexiaFAERS: 1US FAERS
10Chest PainFAERS: 1US FAERS
11Drug dose omissionFAERS: 1US FAERS
12Drug ineffectiveFAERS: 1US FAERS
13Economic problemFAERS: 1US FAERS
14Epigastric discomfortFAERS: 1US FAERS
15Exposure during breast feedingFAERS: 1US FAERS
16Eye irritationFAERS: 1US FAERS
17Hepatitis CFAERS: 1US FAERS
18HepatotoxicityFAERS: 1US FAERS
19LeukopeniaFAERS: 1US FAERS
20PneumoniaFAERS: 1US FAERS
21Throat irritationFAERS: 1US FAERS
22Troponin I increasedFAERS: 1US FAERS
23Ventricular hypokinesiaFAERS: 1US FAERS
24Abnormalities, Drug-Induced10509500CTD
25HIV Infections10509500
14502007
19908326		CTD
26Mitochondrial Diseases10509500CTD
27Mitochondrial Myopathies17545213CTD
28Neurologic Manifestations10509500CTD
29Parkinsonian Disorders19908326CTD
30Pregnancy Complications, Infectious10509500CTD
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