MetaADEDB 2.0 @ LMMD
Dyphylline
(KSCFJBIXMNOVSH-UHFFFAOYSA-N)
Structure
SMILES
OCC(Cn1cnc2c1c(=O)n(C)c(=O)n2C)O
Type(s)
Approved
ATC code(s)
R03DA01; R03DA20; R03DA51; R03DB01
Molecular Formula:
C10H14N4O4
Molecular Weight:
254.243
Log P:
-2.2131
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
2
TPSA:
102.28
CAS Number(s):
479-18-5
Synonym(s)
1.
Dyphylline
2.
Dihydroxypropyltheophylline
3.
Diprophylline
4.
Dilin
5.
Diphylline
6.
Dylix
7.
Lufyllin
8.
Neothylline
External Link(s)
MeSHD004400
PubChem Compound3182
BindingDB82016
ChEBI4728
CHEMBLCHEMBL1752
DrugBankDB00651
DrugCentral976
IUPHAR/BPS Guide to PHARMACOLOGY7070
KEGGcpd:C07819
dr:D00691
Therapeutic Target DatabaseD02PWM
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute myocardial infarctionOFFSIDES
2AgitationSIDER
3Alanine Aminotransferase IncreasedOFFSIDES
4AlbuminuriaSIDER
5Alcoholic IntoxicationOFFSIDES
6Altered state of consciousnessOFFSIDES
7AlveolitisOFFSIDES
8AnalgesiaOFFSIDES
9AnosmiaOFFSIDES
10AspergillosisOFFSIDES
11Aspiration PneumoniaOFFSIDES
12AsthmaOFFSIDES
13Atrioventricular BlockOFFSIDES
14Band neutrophil percentage increasedOFFSIDES
15Blood alkaline phosphatase increasedOFFSIDES
16Blood beta-D-glucan increasedOFFSIDES
17Blood lactate dehydrogenase increasedOFFSIDES
18Blood potassiumOFFSIDES
19Depressed Level of ConsciousnessOFFSIDES
20DiuresisSIDER
21DysgeusiaOFFSIDES
22Epigastric painSIDER
23Erythema MultiformeOFFSIDES
24ErythemaOFFSIDES
25FlushingSIDER
26Gamma-Glutamyltransferase IncreasedOFFSIDES
27HeadacheSIDER
28HyperaldosteronismOFFSIDES
29HypotensionSIDER
30Lymphocyte count decreasedOFFSIDES
31Lymphocyte percentage decreasedOFFSIDES
32Malignant neoplasm progressionOFFSIDES
33Microscopic hematuriaSIDER
34Monocyte percentage decreasedOFFSIDES
35Muscle WeaknessOFFSIDES
36NauseaSIDER
37Neutrophil count decreasedOFFSIDES
38OliguriaOFFSIDES
39PO2 decreasedOFFSIDES
40PalpitationsSIDER
41PolyuriaOFFSIDES
SIDER
42Productive CoughOFFSIDES
43Psychiatric symptomOFFSIDES
44PyelonephritisOFFSIDES
45Renin increasedOFFSIDES
46RhabdomyolysisOFFSIDES
47ShockSIDER
48Sudden deathOFFSIDES
49TachycardiaSIDER
50Ventricular arrhythmiaSIDER
51VomitingSIDER
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