MetaADEDB 2.0 @ LMMD
lafutidine
(KMZQAVXSMUKBPD-DJWKRKHSSA-N)
Structure
SMILES
O=C(CS(=O)Cc1ccco1)NC/C=C\COc1nccc(c1)CN1CCCCC1
Type(s)
Investigational
ATC code(s)
A02BA08
Molecular Formula:
C22H29N3O4S
Molecular Weight:
431.548
Log P:
3.8551
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
1
TPSA:
103.88
CAS Number(s):
118288-08-7; 206449-93-6
Synonym(s)
1.
lafutidine
2.
FRG 8813
3.
FRG-8813
4.
N-(4-(4-piperidinylmethyl)pyridyl-2-oxy)-(Z)-butenyl-2-(furfurylsulfinyl)acetamide
5.
N-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide
External Link(s)
MeSHC076948
PubChem Compound5282136
ChEBI31759
CHEMBLCHEMBL1742461
DrugBankDB12770
DrugCentral1537
KEGGdr:D01131
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute bronchitisOFFSIDES
2Acute myocardial infarctionOFFSIDES
3Acute tonsillitisOFFSIDES
4AdenocarcinomaOFFSIDES
5Alanine Aminotransferase IncreasedOFFSIDES
6Altered state of consciousnessOFFSIDES
7AnorexiaOFFSIDES
8Aortic AneurysmOFFSIDES
9ApathyOFFSIDES
10AscitesOFFSIDES
11Aspiration PneumoniaOFFSIDES
12AsthmaOFFSIDES
13Bacteria urine identifiedOFFSIDES
14Bilirubin conjugated increasedOFFSIDES
15Blood albumin decreasedOFFSIDES
16Blood alkaline phosphatase increasedOFFSIDES
17Blood creatinine increasedOFFSIDES
18Blood lactate dehydrogenase increasedOFFSIDES
19Blood potassium increasedOFFSIDES
20Blood urea increasedOFFSIDES
21Blood uric acidOFFSIDES
22Blood urine presentOFFSIDES
23Blood zinc decreasedOFFSIDES
24Brain ContusionOFFSIDES
25Brain natriuretic peptide increasedOFFSIDES
26Candida pneumoniaOFFSIDES
27Carotid artery aneurysmOFFSIDES
28Cell marker increasedOFFSIDES
29Cerebrovascular stenosisOFFSIDES
30CheilitisOFFSIDES
31Conjunctival depositOFFSIDES
32Coronary angioplastyOFFSIDES
33CryingOFFSIDES
34Cytomegalovirus test positiveOFFSIDES
35Depressed Level of ConsciousnessOFFSIDES
36Disease ProgressionOFFSIDES
37Disseminated Intravascular CoagulationOFFSIDES
38Duodenal Ulcer10671773
11535926		CTD
OFFSIDES
39Duodenal perforationOFFSIDES
40DyslaliaOFFSIDES
41EczemaOFFSIDES
42Ejection Fraction DecreasedOFFSIDES
43EnterocolitisOFFSIDES
44Erythema MultiformeOFFSIDES
45Gamma-Glutamyltransferase IncreasedOFFSIDES
46Gastric ulcerOFFSIDES
47Gastrointestinal perforationOFFSIDES
48GlobulinuriaOFFSIDES
49GlossitisOFFSIDES
50Hepatic congestionOFFSIDES
51HepatosplenomegalyOFFSIDES
52Hypertensive heart diseaseOFFSIDES
53HypopituitarismOFFSIDES
54Infusion site painOFFSIDES
55Infusion site swellingOFFSIDES
56Interleukin-2 receptor increasedOFFSIDES
57Intestinal ObstructionOFFSIDES
58Large intestine perforationOFFSIDES
59Leucine aminopeptidase increasedOFFSIDES
60LeukoencephalopathyOFFSIDES
61Leukopenia neonatalOFFSIDES
62LipaseOFFSIDES
63Liver AbscessOFFSIDES
64Long QT SyndromeOFFSIDES
65Lymphocyte stimulation test positiveOFFSIDES
66Malignant neoplasm progressionOFFSIDES
67Metastases to adrenalsOFFSIDES
68Multiple sclerosis relapseOFFSIDES
69NasopharyngitisOFFSIDES
70Nephrotic SyndromeOFFSIDES
71Neutrophil count decreasedOFFSIDES
72OliguriaOFFSIDES
73Optic Disc EdemaOFFSIDES
74Oral polypectomyOFFSIDES
75Ovarian enlargementOFFSIDES
76Ovarian germ cell teratoma benignOFFSIDES
77Parotid abscessOFFSIDES
78PeriodontitisOFFSIDES
79Peripheral Nervous System Diseases19755835CTD
80PeritonitisOFFSIDES
81Pharyngolaryngeal PainOFFSIDES
82PleurodesisOFFSIDES
83Polymyalgia RheumaticaOFFSIDES
84Polyomavirus-associated nephropathyOFFSIDES
85Postoperative feverOFFSIDES
86Protein total decreasedOFFSIDES
87Pulmonary congestionOFFSIDES
88QuadriplegiaOFFSIDES
89Renin increasedOFFSIDES
90Sclerosing encapsulating peritonitisOFFSIDES
91Shunt malfunctionOFFSIDES
92Small Intestinal StenosisOFFSIDES
93Status EpilepticusOFFSIDES
94Suture ruptureOFFSIDES
95TetanyOFFSIDES
96TonsillitisOFFSIDES
97Tuberculosis test positiveOFFSIDES
98Urobilin urine presentOFFSIDES
99Ventricular FibrillationOFFSIDES
100Vertebral artery occlusionOFFSIDES
101Wound decompositionOFFSIDES
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