MetaADEDB 2.0 @ LMMD
alogliptin
(KEJICOXJTRHYAK-XFULWGLBSA-N)
Structure
SMILES
OC(=O)c1ccccc1.N#Cc1ccccc1Cn1c(cc(=O)n(c1=O)C)N1CCC[C@H](C1)N
Molecular Formula:
C25H27N5O4
Molecular Weight:
461.513
Log P:
2.5446
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
2
TPSA:
134.35
CAS Number(s):
850649-62-6
Synonym(s)
1.
alogliptin
2.
2-((6-((3R)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl) benzonitrile
3.
SYR 322
4.
SYR-322
5.
SYR322
6.
nesina
External Link(s)
MeSHC520853
PubChem Compound16088021
139061539
ChEBI72324
CHEMBLCHEMBL227529
KEGGdr:D06553
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1NauseaFAERS: 15US FAERS
2PancreatitisFAERS: 15US FAERS
3No adverse eventFAERS: 8US FAERS
4Erythema MultiformeFAERS: 7US FAERS
5Intestinal ObstructionFAERS: 7US FAERS
6HeadacheFAERS: 6US FAERS
7PruritusFAERS: 5US FAERS
8Stevens-Johnson SyndromeFAERS: 5US FAERS
9Back PainFAERS: 4US FAERS
10IleusFAERS: 4US FAERS
11RhabdomyolysisFAERS: 4US FAERS
12Toxicity to various agentsFAERS: 4US FAERS
13ConstipationFAERS: 3US FAERS
14DizzinessFAERS: 3US FAERS
15Pancreatic carcinomaFAERS: 3US FAERS
16VomitingFAERS: 3US FAERS
17jaundiceFAERS: 3US FAERS
18Abdominal discomfortFAERS: 2US FAERS
19ArthralgiaFAERS: 2US FAERS
20Cerebrovascular accidentFAERS: 2US FAERS
21Diabetes MellitusFAERS: 2US FAERS
22Drug dispensing errorFAERS: 2US FAERS
23Drug ineffectiveFAERS: 2US FAERS
24InfectionFAERS: 2US FAERS
25Musculoskeletal PainFAERS: 2US FAERS
26Oropharyngeal painFAERS: 2US FAERS
27Seronegative arthritisFAERS: 2US FAERS
28UrticariaFAERS: 2US FAERS
29Accidental exposure to productFAERS: 1US FAERS
30Alanine Aminotransferase IncreasedFAERS: 1US FAERS
31AlopeciaFAERS: 1US FAERS
32Anaphylactoid ReactionFAERS: 1US FAERS
33AngerFAERS: 1US FAERS
34AngioedemaFAERS: 1US FAERS
35Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
36Blood creatine phosphokinase increasedFAERS: 1US FAERS
37Blood creatinine increasedFAERS: 1US FAERS
38Blood potassium increasedFAERS: 1US FAERS
39Cerebral InfarctionFAERS: 1US FAERS
40ChillsFAERS: 1US FAERS
41Cold sweatFAERS: 1US FAERS
42ConjunctivitisFAERS: 1US FAERS
43Depressed Level of ConsciousnessFAERS: 1US FAERS
44Drug administered to patient of inappropriate ageFAERS: 1US FAERS
45Drug prescribing errorFAERS: 1US FAERS
46DysarthriaFAERS: 1US FAERS
47DyspepsiaFAERS: 1US FAERS
48DysphoniaFAERS: 1US FAERS
49FatigueFAERS: 1US FAERS
50FlushingFAERS: 1US FAERS
51FractureFAERS: 1US FAERS
52Helicobacter test positiveFAERS: 1US FAERS
53HypersensitivityFAERS: 1US FAERS
54Immune thrombocytopenic purpuraFAERS: 1US FAERS
55Impaired gastric emptyingFAERS: 1US FAERS
56InfluenzaFAERS: 1US FAERS
57LacerationFAERS: 1US FAERS
58LymphadenopathyFAERS: 1US FAERS
59Mouth swellingFAERS: 1US FAERS
60Musculoskeletal stiffnessFAERS: 1US FAERS
61Myasthenia GravisFAERS: 1US FAERS
62Myocardial InfarctionFAERS: 1US FAERS
63NasopharyngitisFAERS: 1US FAERS
64Occult blood positiveFAERS: 1US FAERS
65Ocular discomfortFAERS: 1US FAERS
66Oculomucocutaneous syndromeFAERS: 1US FAERS
67Oral mucosal erythemaFAERS: 1US FAERS
68OverdoseFAERS: 1US FAERS
69PancytopeniaFAERS: 1US FAERS
70PemphigusFAERS: 1US FAERS
71Peripheral swellingFAERS: 1US FAERS
72Rheumatoid ArthritisFAERS: 1US FAERS
73SinusitisFAERS: 1US FAERS
74SneezingFAERS: 1US FAERS
75StomatitisFAERS: 1US FAERS
76Suicide attemptFAERS: 1US FAERS
77ThrombocytopeniaFAERS: 1US FAERS
78Urethral ObstructionFAERS: 1US FAERS
79Urinary RetentionFAERS: 1US FAERS
80Vulvovaginal pruritusFAERS: 1US FAERS
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