MetaADEDB 2.0 @ LMMD
Rimonabant
(JZCPYUJPEARBJL-UHFFFAOYSA-N)
Structure
SMILES
Clc1ccc(cc1)c1c(C)c(nn1c1ccc(cc1Cl)Cl)C(=O)NN1CCCCC1
Type(s)
Approved; Investigational
ATC code(s)
A08AX01
Molecular Formula:
C22H21Cl3N4O
Molecular Weight:
463.787
Log P:
6.2674
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
1
TPSA:
50.16
CAS Number(s):
168273-06-1
Synonym(s)
1.
Rimonabant
2.
Acomplia
3.
N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride
4.
Rimonabant Hydrochloride
5.
SR 141716
6.
SR 141716A
7.
SR-141716A
8.
SR141716
9.
SR141716A
10.
Zimulti
External Link(s)
MeSHD000077285
PubChem Compound104850
BindingDB27336
21278
ChEBI34967
CHEMBLCHEMBL111
DrugBankDB06155
DrugCentral4150
IUPHAR/BPS Guide to PHARMACOLOGY743
KEGGcpd:C14319
dr:D05731
Therapeutic Target DatabaseD0E0ZR
D0O3OS
D03IYT
ZINC1540228
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal PainSIDER
2Abdominal discomfortSIDER
3Acid refluxOFFSIDES
4AmnesiaSIDER
5Amniotic fluid volume decreasedOFFSIDES
6Amphetamine-Related Disorders15085091CTD
7AngerOFFSIDES
SIDER
8AnorexiaSIDER
9AnxietySIDER
10ApathyOFFSIDES
11AstheniaSIDER
12Blood creatinine increasedOFFSIDES
13Blood glucose abnormalOFFSIDES
14Blood glucose decreasedOFFSIDES
15Blood potassium decreasedOFFSIDES
16Bradycardia9190833CTD
17Bronchoalveolar LavageOFFSIDES
18Cardiac FlutterOFFSIDES
19Caudal Regression SyndromeOFFSIDES
20Choking sensationOFFSIDES
21Cocaine-Related Disorders

View details

11590424
11590440
11821028
17220538
19679410
 		CTD
22Colorectal Neoplasms19479993CTD
23ConfabulationOFFSIDES
24Cytolytic hepatitisOFFSIDES
25DehydrationOFFSIDES
26Depressed moodOFFSIDES
27Depressive disorder19819298CTD
SIDER
28DermatitisSIDER
29Diabetes mellitus inadequate controlOFFSIDES
30DiarrheaOFFSIDES
31DizzinessSIDER
32Dyskinesia, Drug-Induced20888328CTD
33DyspepsiaOFFSIDES
34Dysthymic DisorderSIDER
35Emotional disorderSIDER
36EpilepsyOFFSIDES
37EpistaxisOFFSIDES
38FatigueOFFSIDES
SIDER
39Fatty Liver20110567CTD
40Feelings of worthlessnessOFFSIDES
41GastroenteritisSIDER
42Gastrointestinal PainSIDER
43Hallucinations, mixedOFFSIDES
44HeadacheSIDER
45Hyperalgesia19193902CTD
46Hypotension9190833
10570211		CTD
47InfectionSIDER
48InfestationSIDER
49Inflammation15085199CTD
50InfluenzaSIDER
51Intention tremorOFFSIDES
52Joint sprainSIDER
53Kidney Diseases17882151CTD
54Kidney FailureOFFSIDES
55LethargySIDER
56MalnutritionSIDER
57Memory LossSIDER
58Mental impairmentOFFSIDES
59Mood alterations with depressive symptomsSIDER
60Mood swingsSIDER
61NauseaOFFSIDES
SIDER
62Neoplasms, Experimental16822929CTD
63NervousnessSIDER
64Night sweatsSIDER
65Obesity

View details

18773755
19046740
20110567
20518802
 		CTD
66OliguriaOFFSIDES
67Pain18987195CTD
68ParanoiaSIDER
69ParasomniaSIDER
70Parkinsonian Disorders15894565CTD
71Penile Diseases12946584CTD
72Precancerous Conditions19479993CTD
73Pregnancy Complications16886060CTD
74Proteinuria17882151CTD
75PruritusSIDER
76PyelonephritisOFFSIDES
77SciaticaSIDER
78Seizures12954810CTD
79SinusitisSIDER
80Stevens-Johnson SyndromeOFFSIDES
81Substance Withdrawal Syndrome12968131
15099659		CTD
82Substance-Related Disorders21300050CTD
83TensionSIDER
84TremorSIDER
85Upset stomachSIDER
86Ventricular Dysfunction, Left17678736CTD
87VomitingSIDER
88Weight Gain19030233CTD
OFFSIDES
89nervous system disorderSIDER
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